Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Karnam S. Murthy"'
Publikováno v:
Biomedical Journal, Vol 44, Iss 3, Pp 245-251 (2021)
COVID-19 is a recent pandemic that is still a major health problem of modern times and already more than 17.5 lakhs people succumbed to this deadly disease. This disease is caused by novel coronavirus which is named SARS-COV-2 by the International Co
Externí odkaz:
https://doaj.org/article/f66c6e0e68bb44e79692b288996455de
Autor:
Sunila Mahavadi, Ancy D Nalli, Hongxia Wang, Derek M Kendig, Molly S Crowe, Vijay Lyall, John R Grider, Karnam S Murthy
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209359 (2018)
In gastrointestinal smooth muscle, acetylcholine induced muscle contraction is biphasic, initial peak followed by sustained contraction. Contraction is regulated by phosphorylation of 20 kDa myosin light chain (MLC) at Ser19, interaction of actin and
Externí odkaz:
https://doaj.org/article/a065e35dc5334bd181409ec4303e296e
Publikováno v:
Biomedical Journal
Biomedical Journal, Vol 44, Iss 3, Pp 245-251 (2021)
Biomedical Journal, Vol 44, Iss 3, Pp 245-251 (2021)
COVID-19 is a recent pandemic that is still a major health problem of modern times and already more than 17.5 lakhs people succumbed to this deadly disease. This disease is caused by novel coronavirus which is named SARS-COV-2 by the International Co
Autor:
Chao Li, Emily Rivet, Karnam S. Murthy, John R. Grider, Jaime L. Bohl, Nicole E. Wieghard, John F. Kuemmerle
Publikováno v:
Inflamm Bowel Dis
Background Endoplasmic reticulum (ER) stress is an essential response of epithelial and immune cells to inflammation in Crohn’s disease. The presence and mechanisms that might regulate the ER stress response in subepithelial myofibroblasts (SEMFs)
Publikováno v:
Neurogastroenterology & Motility. 33
Autor:
John R. Grider, Alexander T. May, Molly S. Crowe, Sunila Mahavadi, Hongxia Wang, Karnam S. Murthy, Bryan A. Blakeney
Publikováno v:
Peptides. 112:48-55
The insulinotropic effects of the incretin hormone, glucagon-like peptide-1 (GLP-1) are mediated via GLP-1 receptors (GLP-1R) present on pancreatic β cells. GLP-1 causes a decrease in the motility of stomach and intestine which involves both central
Publikováno v:
Dig Dis Sci
BACKGROUND. Isovaleric Acid (IVA) is a 5-carbon branched chain fatty acid present in fermented foods and produced in the colon by bacterial fermentation of leucine. We previously reported that the shorter, straight chain fatty acids acetate, propiona
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66743 (2013)
We examined expression of protease-activated receptors 2 (PAR2) and characterized their signaling pathways in rabbit gastric muscle cells. The PAR2 activating peptide SLIGRL (PAR2-AP) stimulated Gq, G13, Gi1, PI hydrolysis, and Rho kinase activity, a
Externí odkaz:
https://doaj.org/article/a85e0ebc94db47c09a8aa6a3571b21a2
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility SocietyREFERENCES. 33(2)
Background Duchenne muscular dystrophy (DMD) is characterized by the lack of dystrophin in skeletal, cardiac, and smooth muscle. Slow colonic transit and constipation are common in DMD patients and animal models of DMD. However, the cause of this hyp