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Spatially Localized Entropy-Driven Evolution of Nucleic Acid-Based Constitutional Dynamic Networks for Intracellular Imaging and Spatiotemporal Programmable Gene Therapy.

Autor: Nina Lin, Yu Ouyang, Yunlong Qin, Karmi, Ola, Sohn, Yang Sung, Songqin Liu, Nechushtai, Rachel, Yuanjian Zhang, Willner, Itamar, Zhixin Zhou

Publikováno v: Journal of the American Chemical Society; 7/31/2024, Vol. 146 Issue 30, p20685-20699, 15p

An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters.

Autor: Marjault, Henri-Baptiste^1,2 (AUTHOR), Karmi, Ola^1,3 (AUTHOR), Zuo, Ke^1,2 (AUTHOR), Michaeli, Dorit¹ (AUTHOR), Eisenberg-Domovich, Yael¹ (AUTHOR), Rossetti, Giulia^2,4,5 (AUTHOR), de Chassey, Benoit⁶ (AUTHOR), Vonderscher, Jacky⁶ (AUTHOR), Cabantchik, Ioav¹ (AUTHOR), Carloni, Paolo^2,4,5,7 (AUTHOR), Mittler, Ron³ (AUTHOR), Livnah, Oded¹ (AUTHOR), Meldrum, Eric⁶ (AUTHOR), Nechushtai, Rachel¹ (AUTHOR) Rachel@mail.huji.ac.il

Publikováno v: Communications Biology. 5/10/2022, Vol. 5 Issue 1, p1-9. 9p.

CISD3 is required for Complex I function, mitochondrial integrity, and skeletal muscle maintenance

Autor: Marjault, Henri-Baptiste, Karmi, Ola, Rowland, Linda, Nguyen, Thi Thao, Grant, DeAna, Manrique-Acevedo, Camila, Nechushtai, Rachel, Mittler, Ron

Publikováno v: bioRxiv

Mitochondria play a central role in muscle metabolism and function. In skeletal muscles, a unique family of iron-sulfur proteins, termed CISD proteins, support mitochondrial function. The abundance of these proteins declines with aging leading to mus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::748132cab7b371a72e5dd4a21635379c
https://europepmc.org/articles/PMC10312576/

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