Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Karlo Babakhanian"'
Publikováno v:
Biochemical and Biophysical Research Communications. 361:301-306
P-glycoprotein is a plasma membrane drug efflux protein implicated in extrusion of cytotoxic compounds out of a cell. There is now evidence that suggests expression of this transporter at several subcellular sites, including the nucleus, mitochondria
Autor:
Reina Bendayan, Alexandre Prat, Karlo Babakhanian, Karolina Wosik, Gloria Lee, Manisha Ramaswamy
Publikováno v:
Pharmaceutical Research. 24:1262-1274
The function of ABCG2 (BCRP), a member of the ATP-binding cassette (ABC) superfamily of membrane-associated drug transporters, at the blood-brain barrier remains highly controversial. This project investigates the functional expression of endogenous
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 317:1372-1381
The objectives of this study were to evaluate the potential of a polymer-lipid hybrid nanoparticle (PLN) system to enhance cellular accumulation and retention of doxorubicin (Dox), a widely used anticancer drug and an established P-glycoprotein (Pgp)
Autor:
Reina Bendayan, Andrew M. Rauth, Jiang Liu, Karlo Babakhanian, Xinyue Wang, Qun Liu, Xiao Yu Wu
Publikováno v:
Pharmaceutical research. 26(10)
This work focused on the characterization and in vitro/in vivo evaluation of an alginate/chitosan microsphere (ACMS) formulation of glucose oxidase (GOX) for the locoregional delivery of reactive oxygen species for the treatment of solid tumors.The G
Autor:
Gloria Lee, Karlo Babakhanian, Manisha Ramaswamy, Alexandre Prat, Karolina Wosik, Reina Bendayan
Publikováno v:
Pharmaceutical Research; Jul2007, Vol. 24 Issue 7, p1262-1274, 13p