Výsledky vyhledávání - "Karlijn, Kroon"

Phase I/Ib study with INT-1B3, a novel LNP-formulated micro-RNA (miR-193a-3p mimic) therapeutic for patients with advanced solid cancer

Autor: Harm C. den Boer, Farshid Alemdehy, Bryony J. Telford, Debbie Robbrecht, Nuria Kotecki, Laurens Adrianus Hendricus Van Pinxteren, Sanaz Yahyanejad, Marion T.J. van den Bosch, Karlijn Kroon, Frans L. Opdam, Thijs de Gunst, Rogier M. Vos, Michiel Strijbos, Michel Janicot, Roel Q.J. Schaapveld

Publikováno v: Journal of Clinical Oncology. 39:TPS2666-TPS2666

TPS2666 Background: MicroRNAs (miR) are naturally-occurring small non-coding RNA molecules involved in the regulation of gene expression and their dysregulation plays a fundamental role in several pathological conditions including cancer. The miR-193

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b40cac3009ed1cc2cf8c457ca9ddab2
https://doi.org/10.1200/jco.2021.39.15_suppl.tps2666

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Safety and immunogenicity of TA-HPV, a recombinant vaccinia virus expressing modified human papillomavirus (HPV)-16 and HPV-18 E6 and E7 genes, in women with progressive cervical cancer

Autor: Andreas M, Kaufmann, Peter L, Stern, Elaine M, Rankin, Harald, Sommer, Volkmar, Nuessler, Achim, Schneider, Malcom, Adams, Toli S, Onon, Thomas, Bauknecht, Uwe, Wagner, Karlijn, Kroon, Julian, Hickling, Christopher M, Boswell, Simon N, Stacey, Henry C, Kitchener, Jennifer, Gillard, Jantien, Wanders, John St C, Roberts, Heinz, Zwierzina

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 8(12)

Cervical cancer, the second most common malignancy in women worldwide, is almost invariably associated with infection by human papillomavirus (HPV). HPV-16 or -18 is commonly present in 70% of cervical cancers. HPV-positive tumor cells present antige

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d0f6ab85bb78da3075b9a649beb3594f
https://pubmed.ncbi.nlm.nih.gov/12473576

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