Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Karlie Jones"'
Autor:
Karlie Jones, Angela Ballesteros, Margaret Mentink-Kane, James Warren, Shemona Rattila, Harry Malech, Elizabeth Kang, Gabriela Dveksler
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158050 (2016)
The pregnancy-specific glycoproteins (PSGs) are a family of proteins secreted by the syncytiotrophoblast of the placenta and are the most abundant trophoblastic proteins in maternal blood during the third trimester. The human PSG family consists of 1
Externí odkaz:
https://doaj.org/article/d6de079d1f2447da9cad73dbd11c5fe9
Autor:
Elizabeth M. Kang, Patricia Kiesler, Jian Luo, Sarah Bryant, James Warren, Harry L. Malech, Gabriela S. Dveksler, Sherry Koontz, Karlie Jones
Publikováno v:
Biol Blood Marrow Transplant
Acute graft-versus-host disease (aGVHD) is an immune-mediated reaction that can occur after hematopoietic stem cell transplantation in which donor T cells recognize the host antigens as foreign, destroying host tissues. Establishment of a tolerogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c6d5844ee495aa2e8fb5d455e98360
https://doi.org/10.1016/j.bbmt.2018.09.022
https://doi.org/10.1016/j.bbmt.2018.09.022
Autor:
Benedikt Schoser, Karlie Jones, Christina Wei, Lubov Timchenko, Nikolai A. Timchenko, Giovanni Meola
Publikováno v:
Proceedings of the National Academy of Sciences. 112:8041-8045
Significance Inherited multisystemic diseases, myotonic dystrophies type 1 (DM1) and type 2 (DM2), are caused by long CUG and CCUG RNA repeats. The mutant RNA CCUG repeats should be degraded after intron excision; however, this RNA accumulates in cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62e49d4b88143ecf69f38271424288b
https://doi.org/10.1073/pnas.1422273112
https://doi.org/10.1073/pnas.1422273112
Autor:
Karlie Jones, Elizabeth M. Kang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 13, Iss C, Pp 101-105 (2015)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Allogeneic transplantation can cure many disorders, including sickle cell disease, chronic granulomatous disease (CGD), severe combined immunodeficiency (SCID) and many types of cancers. However, there are several associated risks that can result in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ddc3af1894cfc1208941fdf3e0fc11e
http://www.sciencedirect.com/science/article/pii/S2001037014000531
http://www.sciencedirect.com/science/article/pii/S2001037014000531
Autor:
Elizabeth M. Kang, Robert D. Thompson, Uimook Choi, Harry L. Malech, Karlie Jones, Ji-Liang Gao, Larry E. Rodman
Publikováno v:
Scientific Reports
Agonists that target the A1, A2A, A2B and A3 adenosine receptors have potential to be potent treatment options for a number of diseases, including autoimmune diseases, cardiovascular disease and cancer. Because each of these adenosine receptors plays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347aebe9c8d28871507a2de0575c5ee1
http://europepmc.org/articles/PMC5357845
http://europepmc.org/articles/PMC5357845
Autor:
Shemona Rattila, Harry L. Malech, Angela Ballesteros, Karlie Jones, Gabriela S. Dveksler, James Warren, Margaret M. Mentink-Kane, Elizabeth M. Kang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 7, p e0158050 (2016)
PLoS ONE, Vol 11, Iss 7, p e0158050 (2016)
The pregnancy-specific glycoproteins (PSGs) are a family of proteins secreted by the syncytiotrophoblast of the placenta and are the most abundant trophoblastic proteins in maternal blood during the third trimester. The human PSG family consists of 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d192b9a1ccf4c8c86768f0c358d287c
http://europepmc.org/articles/PMC4936685
http://europepmc.org/articles/PMC4936685
Autor:
Christina Wei, Karlie Jones, Polina Iakova, Enrico Bugiardini, James R. Woodgett, Nikolai A. Timchenko, James M. Killian, Giovanni Meola, Lubov Timchenko, Christiane Schneider-Gold
Publikováno v:
Journal of Clinical Investigation. 122:4461-4472
Myotonic dystrophy type 1 (DM1) is a complex neuromuscular disease characterized by skeletal muscle wasting, weakness, and myotonia. DM1 is caused by the accumulation of CUG repeats, which alter the biological activities of RNA-binding proteins, incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5aa4384aa5998070c0a3255d04e776a
https://doi.org/10.1172/jci64081
https://doi.org/10.1172/jci64081
Autor:
Benedikt Schoser, Nikolai A. Timchenko, Giovanni Meola, Partha S. Sarkar, Claudia Huichalaf, Lubov Timchenko, Bingwen Jin, Karlie Jones, Ann-Bin Shyu, Christiane Schneider-Gold, Polina Iakova
Publikováno v:
The American Journal of Pathology. 179:2475-2489
Expansions of noncoding CUG and CCUG repeats in myotonic dystrophies type 1 (DM1) and DM2 cause complex molecular pathology, the features of which include accumulation of RNA aggregates and misregulation of the RNA-binding proteins muscleblind-like 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e024098c5ec77773777362e8ed4c2f86
https://doi.org/10.1016/j.ajpath.2011.07.013
https://doi.org/10.1016/j.ajpath.2011.07.013
Autor:
Claudia Huichalaf, Karlie Jones, Olivia M. Pereira-Smith, Keiko Sakai, Guo Li Wang, Partha S. Sarkar, Bingwen Jin, Lubov Timchenko, Nikolai A. Timchenko, Benedikt Schoser, Christiane Schneider-Gold
Publikováno v:
The FASEB Journal. 24:3706-3719
The purpose of this study was to investigate the role of the mutant CUGn RNA in the induction of stress in type 1 myotonic dystrophy (DM1) cells and in the stress-mediated inhibition of protein translation in DM1. To achieve our goals, we performed H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7200f2e389650e8dc79ce0d82450f2
https://doi.org/10.1096/fj.09-151159
https://doi.org/10.1096/fj.09-151159
Publikováno v:
PLoS Genetics, Vol 9, Iss 4, p e1003445 (2013)
PLoS Genetics
PLoS Genetics
We report the identification and characterization of a previously unknown suppressor of myopathy caused by expansion of CUG repeats, the mutation that triggers Myotonic Dystrophy Type 1 (DM1). We screened a collection of genes encoding RNA–binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce47c70a69bb27d2eba1e3c49019e9c
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23637619/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23637619/?tool=EBI