Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Karlicek Shannon Marie"'
Autor:
Fannie Chau, Helen Y. Zou, Michele McTigue, Karlicek Shannon Marie, Kevin Ryan, Brion W. Murray, James G. Christensen, Jean Cui, Sergei Timofeevski, Gordon Alton, Jeff Xianchao Zhu
Publikováno v:
Biochemistry. 48:5339-5349
The c-Met receptor tyrosine kinase (RTK) is a key regulator in cancer, in part, through oncogenic mutations. Eight clinically relevant mutants were characterized by biochemical, biophysical, and cellular methods. The c-Met catalytic domain was highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5c208c8e92f08a0a97ca93b219f1c2
https://doi.org/10.1021/bi900438w
https://doi.org/10.1021/bi900438w
Autor:
Stefano F. Liparoto, Melanie Wong, Eric S. Day, Michael Sekar, Donald B. Bennett, Michelle J. Cannon, Dave Casper, Edward J. Collins, Susanne Nyholm Westin, Inna Gorshkova, Yue Jin Li, Karen M. Worthy, Amy Neurauter, Daulet Satpaev, Gerardo R. Marchesini, Paul J. Cachia, Teresa Chu, Ryan James Darling, Jack Simpson, Daniel Kao, Dax A. Rice, Karlicek Shannon Marie, Robert J. Fisher, Magdalena Bynum, Michael Swanson, David G. Myszka, Eric D. Sullivan, Dianne Hodges, Lindsey R. Roberts, Amy M. Liang, Ashique Rafique, Huawei Qiu, Andrew G. Stephen, Giuseppe A. Papalia, Iva Navratilova, Eric Hommema, Béatrice Luginbühl, Jean Inman, Stephen J. Ullrich
Publikováno v:
Analytical Biochemistry 330 (2004) 1
Analytical Biochemistry, 330(1), 98-113
Analytical Biochemistry, 330(1), 98-113
To gauge the experimental variability associated with Biacore analysis, 36 different investigators analyzed a small molecule/enzyme interaction under similar conditions. Acetazolamide (222 g/mol) binding to carbonic anhydrase II (CAII; 30,000 Da) was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f902d2fc2f47b9116e87905fdebf021
https://doi.org/10.1016/j.ab.2004.02.027
https://doi.org/10.1016/j.ab.2004.02.027
Autor:
Patrick B. Lappin, Aidong Wu, Nathan Scott, Farbod Shojaei, Brett H. Simmons, Simon Bergqvist, Eugenia Kraynov, Amanda A Fitzgerald, Joseph H. Lee, Xiaolin Kang, Karlicek Shannon Marie
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 31, Iss 1, p 26 (2012)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Osteopontin (OPN), also known as SPP1 (secreted phosphoprotein), is an integrin binding glyco-phosphoprotein produced by a variety of tissues. In cancer patients expression of OPN has been associated with poor prognosis in several tumor types includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2459de237c61b21457e790463d297d38
http://www.jeccr.com/content/31/1/26
http://www.jeccr.com/content/31/1/26
Autor:
Tod Smeal, Karlicek Shannon Marie, Kephart Susan Elizabeth, Jane Lamerdin, Marakovits Joseph T, Eleanor Dagostino, Chuangxing Guo, Joseph Piraino, John Westwick, Michael Zager, Daniel R. Knighton, Simon Bergqvist, Brion W. Murray, James G. Christensen, Cho-Ming Loi, Ricardo Martinez, Cathy Zhang, Eugenia Kraynov, Ian Popoff
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(20)
Despite abundant evidence that aberrant Rho-family GTPase activation contributes to most steps of cancer initiation and progression, there is a dearth of inhibitors of their effectors (e.g., p21-activated kinases). Through high-throughput screening a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1c2a25c2007cf3d3777e2c19b4e847
https://pubmed.ncbi.nlm.nih.gov/20439741
https://pubmed.ncbi.nlm.nih.gov/20439741
Autor:
Ya-Li Deng, Sergei Timofeevski, Brion W. Murray, Ben Bolaños, Wei Liu, Simon Bergqvist, Alexei Brooun, Michele McTigue, Karlicek Shannon Marie
Publikováno v:
Cancer Research. 73:4456-4456
Anaplastic lymphoma kinase (ALK), when aberrantly regulated through gene translocations or mutations, has been implicated as an oncogenic driver in a variety of cancers. XALKORI (crizotinib) is an FDA-approved therapy for locally advanced or metastat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01768ae730e865810b98f40fff8b9861
https://doi.org/10.1158/1538-7445.am2013-4456
https://doi.org/10.1158/1538-7445.am2013-4456