Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Karlee Silver"'
Autor:
Marek Lalli, Harriet Ruysen, Hannah Blencowe, Kristen Yee, Karen Clune, Mary DeSilva, Marissa Leffler, Emily Hillman, Haitham El-Noush, Jo Mulligan, Jeffrey C. Murray, Karlee Silver, Joy E. Lawn
Publikováno v:
Globalization and Health, Vol 14, Iss 1, Pp 1-12 (2018)
Abstract Background Grand Challenges for international health and development initiatives have received substantial funding to tackle unsolved problems; however, evidence of their effectiveness in achieving change is lacking. A theory of change may p
Externí odkaz:
https://doaj.org/article/aad0e80c01af4a06a14218dc4ea3a4b4
Autor:
Till Bärnighausen, Seth Berkley, Zulfiqar A Bhutta, David M Bishai, Maureen M Black, David E Bloom, Dagna Constenla, Julia Driessen, John Edmunds, David Evans, Ulla Griffiths, Peter Hansen, Farah Naz Hashmani, Raymond Hutubessy, Dean T Jamison, Prabhat Jha, Mark Jit, Hope Johnson, Ramanan Laxminarayan, Bruce Y Lee, Sharmila Mhatre, Anne Mills, Anders Nordström, Sachiko Ozawa, Lisa Prosser, Karlee Silver, Christine Stabell Benn, Baudouin Standaert, Damian Walker
Publikováno v:
The Lancet Global Health, Vol 2, Iss 5, Pp e251-e252 (2014)
Externí odkaz:
https://doaj.org/article/df33ef07b69046c2a6b59445f2299112
Autor:
Karlee Silver, Thomas Mason, Christopher C. Goodnow, Shirine Chaudhry, Tiphaine Bouriez-Jones, Ian Roberts, Andrew J. Rimmer, Tertius A Hough, Tanya L. Crockford, Richard J. Cornall, Katherine R. Bull
Publikováno v:
The Journal of Pathology
The study of mutations causing the steroid-resistant nephrotic syndrome in children has greatly advanced our understanding of the kidney filtration barrier. In particular, these genetic variants have illuminated the roles of the podocyte, glomerular
Autor:
Teresa Lambe, Anastasia Nijnik, Karlee Silver, Richard J. Cornall, Helen Ferry, Graham Lewis, Janson C. H. Leung
Autoreactive B cells are actively tolerized to more abundant self-antigens by a series of checkpoints involving receptor editing, deletion, anergy and competition for growth factors. In contrast, B cells reactive against rare, sequestered or tissue s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089ce042f25aa4c0f79575c3f0351828
https://ora.ox.ac.uk/objects/uuid:7028df01-9f5e-4610-bc4a-1d425b5d250a
https://ora.ox.ac.uk/objects/uuid:7028df01-9f5e-4610-bc4a-1d425b5d250a
Autor:
Helen Ferry, Janson C. H. Leung, John V. Forrester, Kimmo Makinen, Teresa Lambe, Tiphaine Bouriez-Jones, Karlee Silver, Richard J. Cornall, Tanya L. Crockford
Publikováno v:
ResearcherID
Better understanding of tolerance and autoimmunity toward melanocyte-specific Ags is needed to develop effective treatment for vitiligo and malignant melanoma; yet, a systematic assessment of these mechanisms has been hampered by the difficulty in tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a1e3627ac2ee3d9fad015e3e114434
https://doi.org/10.4049/jimmunol.177.5.3055
https://doi.org/10.4049/jimmunol.177.5.3055
Autor:
Stephen Martin, Sarah L. Pogue, Karlee Silver, Christopher C. Goodnow, Kaiman Peng, Kiyoshi Takatsu, Keisuke Horikawa
Publikováno v:
The Journal of Experimental Medicine
Immunological memory is characterized by heightened immunoglobulin (Ig) G antibody production caused in part by enhanced plasma cell formation conferred by conserved transmembrane and cytoplasmic segments in isotype-switched IgG B cell receptors. We
Publikováno v:
European Journal of Immunology. 36:1404-1412
Toll-like receptors (TLR) have been shown to play an essential role in the generation of autoantibodies in mouse models of autoimmunity, but the timing and context of these effects are poorly understood. One hypothesis is that TLR ligands assist in t
Autor:
Karlee Silver, Simon Milling, Teresa Lambe, Richard J. Cornall, Tanya L. Crockford, Tiphaine Bouriez-Jones
Publikováno v:
European journal of immunology. 37(10)
Recent evidence suggests that systemic autoimmune disease depends on signals from TLR ligands, but little is known about how TLR-dependent pathways lead to the loss of self tolerance in vivo. To address this, we have examined the role of TLR signalin
Autor:
Karlee Silver, Richard J. Cornall, Jason G. Cyster, Tiphaine Bouriez-Jones, Helen Ferry, Tanya L. Crockford, H L Tang
Publikováno v:
European journal of immunology. 36(11)
IgG autoantibodies cause pathology due to their ability to bind self antigens. However, the extent to which the initial B cell activation and isotype switching is antigen-driven is unclear and it has been widely proposed that intrinsic B cell hyperac
Autor:
Nigel Rust, Helen Ferry, Christopher C. Goodnow, Karlee Silver, Tanya L. Crockford, Richard J. Cornall
Publikováno v:
European Journal of Immunology. 35:3714-3714