Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Karla de Melo Lima"'
Autor:
José Maciel Rodrigues Júnior, Karla de Melo Lima, Arlete Aparecida Martins Coelho Castelo, Vânia Luiza Deperon Bonato Martins, Sandra Aparecida dos Santos, Lucia Helena Faccioli, Célio Lopes Silva
Publikováno v:
Jornal Brasileiro de Pneumologia, Vol 30, Iss 4, Pp 378-387 (2004)
Vacinas de DNA, ainda em fase de experimentação e testes clínicos, podem se tornar uma importante ferramenta de combate a doenças infecciosas para as quais, até hoje, não existe prevenção segura e eficaz, como a tuberculose. Nos últimos anos
Externí odkaz:
https://doaj.org/article/7bb574b63d30435b9538a019a4f15d62
Autor:
Jorge Kalil, Cristina Caldas, Edilberto Postol, E. Luna, J. M. Rodrigues, Verônica Coelho, Karla De Melo Lima, Luiz Alberto Benvenuti
Publikováno v:
Scandinavian Journal of Immunology. 66:62-70
The increased expression of heat shock protein (Hsp)60 in different kinds of graft tissues has been associated with a proinflammatory role and rejection. However, there are very few reports in which treatment with Hsp60 delays skin allograft rejectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3cebe621a22a688ffab30800a7760ba
https://doi.org/10.1111/j.1365-3083.2007.01951.x
https://doi.org/10.1111/j.1365-3083.2007.01951.x
Autor:
Maria Vitória Lopes Badra Bentley, Roberto Nicolete, Lúcia Helena Faccioli, Célio Lopes Silva, Alexandra Ivo de Medeiros, José Maciel Rodrigues Júnior, Karla De Melo Lima, Marcelo Dias Baruffi
Publikováno v:
Prostaglandins & Other Lipid Mediators. 83:121-129
Leukotriene B 4 (LTB 4 ) is a potent inflammatory mediator and stimulates the immune response. In addition, LTB 4 promotes leukocyte functions such as phagocytosis, chemotaxis and chemokinesis of polymorphonuclear leukocytes, as well as modulates cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abaee905acd6a53c1229ad08775304a9
https://doi.org/10.1016/j.prostaglandins.2006.10.007
https://doi.org/10.1016/j.prostaglandins.2006.10.007
Autor:
Izaíra T. Brandão, Célio Lopes Silva, Maristela Ruberti, José Maciel Rodrigues Júnior, Sandra Aparecida dos Santos, Edson Garcia Soares, Karla De Melo Lima
Publikováno v:
Journal of Drug Targeting. 12:195-203
We evaluated the use of a vaccine formulation based on a mixture of two different PLGA microspheres, composed by faster and slower release profiles, containing DNA encoding hsp65 and the recombinant hsp65 protein, respectively, aiming to DNA priming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2a5262886871c6be47ee66d63700c5
https://doi.org/10.1080/10611860410001723126
https://doi.org/10.1080/10611860410001723126
Autor:
S.M.A. dos Santos, Rubens R. Dos Santos, Juliana Rodrigues, Izaíra T. Brandão, Karla De Melo Lima, Célio Lopes Silva
Publikováno v:
Vaccine. 22:49-56
A DNA vaccine codifying the mycobacterial hsp65 can prevent infection with Mycobacterium tuberculosis in a prophylactic setting and also therapeutically reduce the number of bacteria in infected mice. The protective mechanism is thought to be related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0419fbf6bc38ed815a11ca08831ba6
https://doi.org/10.1016/s0264-410x(03)00543-7
https://doi.org/10.1016/s0264-410x(03)00543-7
Autor:
Marta Maria Gontijo De Aguiar, José Maciel Rodrigues Júnior, Carlos Eduardo de Matos Jensen, Armando da Silva Cunha Júnior, Karla De Melo Lima
Publikováno v:
Artificial Organs. 27:492-497
In this work we describe the development and characterization of a new formulation of insulin (INS). Insulin was complexed with cyclodextrins (CD) in order to improve its solubility and stability being available as a dry powder, after encapsulation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d3ceb9b0adfb178b01fcf9612bc9b6e
https://doi.org/10.1046/j.1525-1594.2003.07244.x
https://doi.org/10.1046/j.1525-1594.2003.07244.x
Autor:
José M. Rodrigues-Junior, Rubens R. Dos Santos, Karla De Melo Lima, Célio Lopes Silva, Izaíra T. Brandão, Vania L. D. Bonato, E. D. C. Gonçalves, Sandra Aparecida dos Santos, Valéria Marçal Felix de Lima, Lúcia Helena Faccioli
Publikováno v:
Infection and Immunity. 69:5305-5312
Mice treated with viableMycobacterium tuberculosiswith no glycolipid trehalose dimycolate (TDM) on the outer cell wall (delipidatedM. tuberculosis) by intraperitoneal or intratracheal inoculation presented an intense recruitment of polymorphonuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb246029f8efee529fd08e874165e46
https://doi.org/10.1128/iai.69.9.5305-5312.2001
https://doi.org/10.1128/iai.69.9.5305-5312.2001
Autor:
Peter J. Jose, Roberto Nicolete, Karla De Melo Lima, Maria-Jesus Sanz, Lúcia Helena Faccioli, José Maciel Rodrigues Júnior
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 70(3)
PGE(2), an arachidonic acid metabolite produced by various type of cells regulates a broad range of physiological activities in the endocrine, cardiovascular, gastrointestinal, and immune systems, and is involved in maintaining the local homeostasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7724e06df7c350d8eed19a8c60ce10b8
https://pubmed.ncbi.nlm.nih.gov/18640269
https://pubmed.ncbi.nlm.nih.gov/18640269
Autor:
Constance Oliver, Alan R. Prescott, Ana Paula Favaro Trombone, Maria Célia Jamur, Karla De Melo Lima, Célio Lopes Silva, Arlete Aparecida Martins Coelho-Castelo
Publikováno v:
PLoS ONE, Vol 2, Iss 9, p e923 (2007)
PLoS ONE
PLoS ONE
BACKGROUND: Experimental models using DNA vaccine has shown that this vaccine is efficient in generating humoral and cellular immune responses to a wide variety of DNA-derived antigens. Despite the progress in DNA vaccine development, the intracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57041cf4ba70d33c5a8264624c8ba55d
http://europepmc.org/articles/PMC1976595?pdf=render
http://europepmc.org/articles/PMC1976595?pdf=render
Autor:
J.M Rodrigues-Junior, Célio Lopes Silva, Lúcia Helena Faccioli, Karla De Melo Lima, Arlete Am Coelho-Castelo, Vânia Luiza Deperon Bonato
Publikováno v:
Annual Review of Biomedical Sciences. 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f268ac5fbb814d9102683952e1fd6e84
https://doi.org/10.5016/1806-8774.2000v2p39
https://doi.org/10.5016/1806-8774.2000v2p39