Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Karla V, Allebrandt"'
Autor:
Samuel E. Jones, Jacqueline M. Lane, Andrew R. Wood, Vincent T. van Hees, Jessica Tyrrell, Robin N. Beaumont, Aaron R. Jeffries, Hassan S. Dashti, Melvyn Hillsdon, Katherine S. Ruth, Marcus A. Tuke, Hanieh Yaghootkar, Seth A. Sharp, Yingjie Jie, William D. Thompson, Jamie W. Harrison, Amy Dawes, Enda M. Byrne, Henning Tiemeier, Karla V. Allebrandt, Jack Bowden, David W. Ray, Rachel M. Freathy, Anna Murray, Diego R. Mazzotti, Philip R. Gehrman, Debbie A. Lawlor, Timothy M. Frayling, Martin K. Rutter, David A. Hinds, Richa Saxena, Michael N. Weedon
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
GWAS have previously found 24 genomic loci associated with chronotype, an individual’s preference for early or late sleep timing. Here, the authors identify 327 additional loci in a sample of 697,828 individuals and further explore the relationship
Externí odkaz:
https://doaj.org/article/7d76303f46514c92adc6ac6228d3ae3f
Autor:
Karla V. Allebrandt, Maris Teder-Laving, Paola Cusumano, Goar Frishman, Rosa Levandovski, Andreas Ruepp, Maria P. L. Hidalgo, Rodolfo Costa, Andres Metspalu, Till Roenneberg, Cristiano De Pittà
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Recognizing that insights into the modulation of sleep duration can emerge by exploring the functional relationships among genes, we used this strategy to explore the genome-wide association results for this trait. We detected two major sign
Externí odkaz:
https://doaj.org/article/63089e19cbdc46febc44f47d63b77f62
Autor:
Samuel E Jones, Jessica Tyrrell, Andrew R Wood, Robin N Beaumont, Katherine S Ruth, Marcus A Tuke, Hanieh Yaghootkar, Youna Hu, Maris Teder-Laving, Caroline Hayward, Till Roenneberg, James F Wilson, Fabiola Del Greco, Andrew A Hicks, Chol Shin, Chang-Ho Yun, Seung Ku Lee, Andres Metspalu, Enda M Byrne, Philip R Gehrman, Henning Tiemeier, Karla V Allebrandt, Rachel M Freathy, Anna Murray, David A Hinds, Timothy M Frayling, Michael N Weedon
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006125 (2016)
Disrupted circadian rhythms and reduced sleep duration are associated with several human diseases, particularly obesity and type 2 diabetes, but until recently, little was known about the genetic factors influencing these heritable traits. We perform
Externí odkaz:
https://doaj.org/article/80eac3f9df0149afabc3a13a112d8fb9
Publikováno v:
Molecular Genetics and Metabolism. 121:43-50
Genome-wide association studies (GWAs) for type 2 diabetes (T2D) have been successful in identifying many loci with robust association signals. Nevertheless, there is a clear need for post-GWAs strategies to understand mechanism of action and clinica
Autor:
Ewan R. Pearson, Dennis Mook-Kanamori, Jessica Tyrrell, Yingjie Ji, Hanieh Yaghootkar, Alex I. Blakemore, Louise Thomas, Karla V. Allebrandt, Jimmy Bell, Renée De Mutsert, Samuel E. Jones, Beaumont Rn, Andrianos M. Yiorkas, H Staiger, Francesca Frau, Andrew R. Wood, Timothy M. Frayling, Norbert Stefan
Publikováno v:
Diabetes. 67
Genetic studies have identified “favourable adiposity” variants - where the allele associated with higher adiposity is associated with lower risk of type 2 diabetes. We took a novel approach to find more of these alleles and find the underlying m
Autor:
Anna Murray, Francesca Frau, Dennis O. Mook-Kanamori, Samuel E. Jones, Andrianos M. Yiorkas, Michael N. Weedon, Rachel M. Freathy, Andrew R. Wood, Andrew T. Hattersley, Ewan R. Pearson, Harald Staiger, Hanieh Yaghootkar, Robin N Beaumont, Caroline Hayward, Marcus A. Tuke, Alexandra I. F. Blakemore, Hans-Ulrich Häring, Norbert Stefan, Renée de Mutsert, Anubha Mahajan, Archie Campbell, Timothy M. Frayling, Jessica Tyrrell, Jürgen Machann, Karla V. Allebrandt, Yingjie Ji, Jimmy D. Bell, Naeimeh Atabaki-Pasdar, Katherine S. Ruth, E. Louise Thomas, Paul W. Franks
Publikováno v:
Ji, Y, Yiorkas, A M, Frau, F, Mook-kanamori, D, Staiger, H, Thomas, E L, Atabaki-pasdar, N, Campbell, A, Tyrrell, J, Jones, S E, Beaumont, R N, Wood, A R, Tuke, M A, Ruth, K S, Mahajan, A, Murray, A, Freathy, R M, Weedon, M N, Hattersley, A T, Hayward, C, Machann, J, Häring, H, Franks, P, De Mutsert, R, Pearson, E, Stefan, N, Frayling, T M, Allebrandt, K V, Bell, J D, Blakemore, A I & Yaghootkar, H 2018, ' Genome-Wide and Abdominal MRI-Imaging Data Provides Evidence that a Genetically Determined Favourable Adiposity Phenotype is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease and Hypertension ', Diabetes, pp. db180708 . https://doi.org/10.2337/db18-0708
Diabetes, 68(1), 207-219
Diabetes 68, 207-219 (2019)
Diabetes, 68(1), 207-219
Diabetes 68, 207-219 (2019)
Recent genetic studies have identified alleles associated with opposite effects on adiposity and risk of type 2 diabetes. We aimed to identify more of these variants and test the hypothesis that such “favourable adiposity” alleles are associated
Autor:
Dorret I. Boomsma, Søren Brunak, Adem Y. Dawed, Gonneke Willemsen, Mark I. McCarthy, Martijn van de Bunt, Karina Banasik, Leen M 't Hart, Valborg Gudmundsdottir, Mark H. H. Kramer, Jorge Ferrer, Eco J. C. de Geus, Axel Dietrich, Caroline Brorsson, Ramneek Gupta, A.M.C. Simonis-Bik, Anubha Mahajan, Elisabeth M. W. Eekhoff, Hans-Ulrich Häring, Thomas Hübschle, Christopher J. Groves, Andreas Fritsche, Harald Staiger, Joris Deelen, Karla V. Allebrandt, Helle Krogh Pedersen, Nienke van Leeuwen, Ewan R. Pearson
Publikováno v:
PLoS ONE, 13(1)
PLoS One
PLoS ONE
Gudmundsdottir, V, Pedersen, H K, Allebrandt, K V, Brorsson, C A, van Leeuwen, N, Banasik, K, Mahajan, A, Groves, C J, van de Bunt, M, Dawed, A Y, Fritsche, A, Staiger, H, Simonis-Bik, A M C, Deelen, J, Kramer, M H H, Dietrich, A, Hübschle, T, Willemsen, G, Häring, H-U, de Geus, E J C, Boomsma, D I, Eekhoff, E M W, Ferrer, J, McCarthy, M I, Pearson, E R, Gupta, R, Brunak, S & 't Hart, L M 2018, ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion : A DIRECT study ', P L o S One, vol. 13, no. 1, e0189886, pp. 1-19 . https://doi.org/10.1371/journal.pone.0189886
PLoS ONE, 13(1):e0189886. Public Library of Science
PLoS ONE, Vol 13, Iss 1, p e0189886 (2018)
Gudmundsdottir, V, Pedersen, H K, Allebrandt, K V, Brorsson, C A, van Leeuwen, N, Banasik, K, Mahajan, A, Groves, C J, van de Bunt, M, Dawed, A Y, Fritsche, A, Staiger, H, Simonis-Bik, A M C, Deelen, J, Kramer, M H H, Dietrich, A, Hübschle, T, Willemsen, G, Häring, H-U, de Geus, E J C, Boomsma, D I, Eekhoff, E M W, Ferrer, J, McCarthy, M I, Pearson, E R, Gupta, R, Brunak, S & 't Hart, L M 2018, ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study ', P L o S One, vol. 13, no. 1, e0189886 . https://doi.org/10.1371/journal.pone.0189886
Gudmundsdottir, V, Pedersen, H K, Allebrandt, K V, Brorsson, C, van Leeuwen, N, Banasik, K, Mahajan, A, Groves, C J, de Bunt, M V, Dawed, A Y, Fritsche, A, Staiger, H, Simonis-Bik, A M C, Deelen, J, Kramer, M H H, Dietrich, A, Hübschle, T, Willemsen, G, Häring, H U, de Geus, E J C, Boomsma, D I, Eekhoff, E M W, Ferrer, J, McCarthy, M I, Pearson, E R, Gupta, R, Brunak, S & t Hart, L M 2018, ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion : A DIRECT study ', PLoS ONE, vol. 13, no. 1, e0189886 . https://doi.org/10.1371/journal.pone.0189886
Gudmundsdottir, V, Pedersen, H K, Allebrandt, K V, Brorsson, C, van Leeuwen, N, Banasik, K, Mahajan, A, Groves, C J, van de Bunt, M, Dawed, A Y, Fritsche, A, Staiger, H, Simonis-Bik, A M C, Deelen, J, Kramer, M H H, Dietrich, A, Hübschle, T, Willemsen, G, Häring, H-U, de Geus, E J C, Boomsma, D I, Eekhoff, E M W, Ferrer, J, McCarthy, M I, Pearson, E R, Gupta, R, Brunak, S & 't Hart, L M 2018, ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion : A DIRECT study ', PLoS ONE, vol. 13, no. 1, e0189886, pp. e0189886 . https://doi.org/10.1371/journal.pone.0189886
PLoS One
PLoS ONE
Gudmundsdottir, V, Pedersen, H K, Allebrandt, K V, Brorsson, C A, van Leeuwen, N, Banasik, K, Mahajan, A, Groves, C J, van de Bunt, M, Dawed, A Y, Fritsche, A, Staiger, H, Simonis-Bik, A M C, Deelen, J, Kramer, M H H, Dietrich, A, Hübschle, T, Willemsen, G, Häring, H-U, de Geus, E J C, Boomsma, D I, Eekhoff, E M W, Ferrer, J, McCarthy, M I, Pearson, E R, Gupta, R, Brunak, S & 't Hart, L M 2018, ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion : A DIRECT study ', P L o S One, vol. 13, no. 1, e0189886, pp. 1-19 . https://doi.org/10.1371/journal.pone.0189886
PLoS ONE, 13(1):e0189886. Public Library of Science
PLoS ONE, Vol 13, Iss 1, p e0189886 (2018)
Gudmundsdottir, V, Pedersen, H K, Allebrandt, K V, Brorsson, C A, van Leeuwen, N, Banasik, K, Mahajan, A, Groves, C J, van de Bunt, M, Dawed, A Y, Fritsche, A, Staiger, H, Simonis-Bik, A M C, Deelen, J, Kramer, M H H, Dietrich, A, Hübschle, T, Willemsen, G, Häring, H-U, de Geus, E J C, Boomsma, D I, Eekhoff, E M W, Ferrer, J, McCarthy, M I, Pearson, E R, Gupta, R, Brunak, S & 't Hart, L M 2018, ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study ', P L o S One, vol. 13, no. 1, e0189886 . https://doi.org/10.1371/journal.pone.0189886
Gudmundsdottir, V, Pedersen, H K, Allebrandt, K V, Brorsson, C, van Leeuwen, N, Banasik, K, Mahajan, A, Groves, C J, de Bunt, M V, Dawed, A Y, Fritsche, A, Staiger, H, Simonis-Bik, A M C, Deelen, J, Kramer, M H H, Dietrich, A, Hübschle, T, Willemsen, G, Häring, H U, de Geus, E J C, Boomsma, D I, Eekhoff, E M W, Ferrer, J, McCarthy, M I, Pearson, E R, Gupta, R, Brunak, S & t Hart, L M 2018, ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion : A DIRECT study ', PLoS ONE, vol. 13, no. 1, e0189886 . https://doi.org/10.1371/journal.pone.0189886
Gudmundsdottir, V, Pedersen, H K, Allebrandt, K V, Brorsson, C, van Leeuwen, N, Banasik, K, Mahajan, A, Groves, C J, van de Bunt, M, Dawed, A Y, Fritsche, A, Staiger, H, Simonis-Bik, A M C, Deelen, J, Kramer, M H H, Dietrich, A, Hübschle, T, Willemsen, G, Häring, H-U, de Geus, E J C, Boomsma, D I, Eekhoff, E M W, Ferrer, J, McCarthy, M I, Pearson, E R, Gupta, R, Brunak, S & 't Hart, L M 2018, ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion : A DIRECT study ', PLoS ONE, vol. 13, no. 1, e0189886, pp. e0189886 . https://doi.org/10.1371/journal.pone.0189886
Glucagon-like peptide 1 (GLP-1) stimulated insulin secretion has a considerable heritable component as estimated from twin studies, yet few genetic variants influencing this phenotype have been identified. We performed the first genome-wide associati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9489b2fe6f8e6eb1c32fb0ecab54e1
http://hdl.handle.net/1887/76801
http://hdl.handle.net/1887/76801
Autor:
Rosa Maria Levandovski, Rodolfo Costa, Paola Cusumano, Karla V. Allebrandt, Andreas Ruepp, Maris Teder-Laving, Goar Frishman, Cristiano De Pittà, Andres Metspalu, Maria Paz Loayza Hidalgo, Till Roenneberg
Publikováno v:
Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
Sci. Rep. 7:4555 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
Sci. Rep. 7:4555 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Recognizing that insights into the modulation of sleep duration can emerge by exploring the functional relationships among genes, we used this strategy to explore the genome-wide association results for this trait. We detected two major signalling pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67af1a6fcc508f7a38cd47a8582d31d7
Autor:
Igor Rudan, Tõnu Esko, Wilfred F. J. van IJcken, Alan F. Wright, Caroline Hayward, Nathaniel F. Watson, Ben A. Oostra, Karla V. Allebrandt, Scott A. Melville, Steven R. Cummings, Aaron Isaacs, Gonneke Willemsen, Yurii S. Aulchenko, Albert Hofman, Fran Borovečki, Maris Teder-Laving, Sina A. Gharib, Brenda W.J.H. Penninx, Cornelia M. van Duijn, Josine G. van Mill, Dorret I. Boomsma, Harry Campbell, James F. Wilson, Katie L. Stone, Rutger W W Brouwer, Philip R. Gehrman, Annemarie I. Luik, Ozren Polasek, Naresh M. Punjabi, Jouke-Jan Hottenga, Jennifer E. Huffman, Daniel S. Evans, Martina Müller-Nurasyid, Ashley van der Spek, Andrew A. Hicks, Susan Redline, Peter P. Pramstaller, Fabiola M. Del Greco, Rudolf S N Fehrmann, Bertram Müller-Myhsok, Nicole Vogelzangs, Man Li, Lude Franke, Edwin Oole, Ayse Demirkan, Lina Zgaga, Karin Hek, Mirjam C G N van den Hout, Wen Hong Linda Kao, Gregory J. Tranah, Enda M. Byrne, Bruce M. Psaty, Hamdi Mbarek, Martha Merrow, Kristin D. Marciante, Josef Coresh, Henning Tiemeier, Grant W. Montgomery, Till Roenneberg, Susan Campbell, Ivana Kolcic, Juha Karjalainen, Zoran Dogas, Andres Metspalu, Ting Hsu Chen, Najaf Amin, André G. Uitterlinden, Nicholas G. Martin, Daniel J. Gottlieb, Andrew C. Heath, Thomas Meitinger, Heinz Erich Wichmann, Jacqueline M. Vink, Evelin Mihailov
Publikováno v:
European Journal of Human Genetics, 24(10), 1488-1495. Nature Publishing Group
Amin, N, Allebrandt, K V, van der Spek, A, Mueller-Myhsok, B, Hek, K, Teder-Laving, M, Hayward, C, Esko, T, van Mill, J G, Mbarek, H, Watson, N F, Melville, S A, Del Greco, F M, Byrne, E M, Oole, E, Kolcic, I, Chen, T, Evans, D S, Coresh, J, Vogelzangs, N, Karjalainen, J, Willemsen, G, Gharib, S A, Zgaga, L, Mihailov, E, Stone, K L, Campbell, H, Brouwer, R W, Demirkan, A, Isaacs, A, Dogas, Z, Marciante, K D, Campbell, S, Borovecki, F, Luik, A I, Li, M, Hottenga, J J, Huffman, J E, van den Hout, M C G N, Cummings, S R, Aulchenko, Y S, Gehrman, P R, Uitterlinden, A G, Wichmann, H-E, Muller-Nurasyid, M, Fehrmann, R S N, Montgomery, G W, Hofman, A, Kao, W H L, Oostra, B A, Wright, A F, Vink, J M, Wilson, J F, Pramstaller, P P, Hicks, A A, Polasek, O, Punjabi, N M, Redline, S, Psaty, B M, Heath, A C, Merrow, M, Tranah, G J, Gottlieb, D J, Boomsma, D I, Martin, N G, Rudan, I, Tiemeier, H, van IJcken, W F J, Penninx, B W, Metspalu, A, Meitinger, T, Franke, L, Roenneberg, T & van Duijn, C M 2016, ' Genetic variants in RBFOX3 are associated with sleep latency ', European Journal of Human Genetics, vol. 24, no. 10, pp. 1488-1495 . https://doi.org/10.1038/ejhg.2016.31
European Journal of Human Genetics, 24, 1488-1495
European Journal of Human Genetics, 24, 10, pp. 1488-1495
EUROPEAN JOURNAL OF HUMAN GENETICS
Eur. J. Hum. Genet. 24, 1488-1495 (2016)
Amin, N, Allebrandt, K V, Spek, A, Müller-Myhsok, B, Hek, K, Teder-Laving, M, Hayward, C, Esko, T, van Mill, J G, Mbarek, H, Watson, N F, Melville, S A, Del Greco, M F, Byrne, E M, Oole, E, Kolcic, I, Chen, T, Evans, D S, Coresh, J, Vogelzangs, N, Karjalainen, J, Willemsen, G, Gharib, S A, Zgaga, L, Mihailov, E, Stone, K L, Campbell, H, Brouwer, R W W, Demirkan, A, Isaacs, A, Dogas, Z, Marciante, K, Campbell, S, Borovecki, F, Luik, A I, Li, M, Hottenga, J J, Huffman, J E, van den Hout, M C G N, Cummings, S R, Aulchenko, Y S, Gehrman, P R, Uitterlinden, A G, Wichmann, H E, Müller-Nurasyid, M, Fehrmann, R S N, Montgomery, G W, Hofman, A, Hong, W, Kao, L, Oostra, B A, Wright, A F, Vink, J M, Wilson, J F, Pramstaller, P P, Hicks, A A, Polasek, O, Punjabi, N M, Redline, S, Psaty, B M, Heath, A C, Merrow, M, Tranah, G J, Gottlieb, D J, Boomsma, D I, Martin, N G, Rudan, I, Tiemeier, H, van Ijcken, W F J, Penninx, B W J H, Metspalu, A, Meitinger, T, Franke, L, Roenneberg, T & van Duijn, C M 2016, ' Genetic variants in RBFOX3 are associated with sleep latency ', European Journal of Human Genetics, vol. 24, no. 10, pp. 1488-1495 . https://doi.org/10.1038/ejhg.2016.31
European Journal of Human Genetics
Amin, N, Allebrandt, K V, van der Spek, A, Mueller-Myhsok, B, Hek, K, Teder-Laving, M, Hayward, C, Esko, T, van Mill, J G, Mbarek, H, Watson, N F, Melville, S A, Del Greco, F M, Byrne, E M, Oole, E, Kolcic, I, Chen, T, Evans, D S, Coresh, J, Vogelzangs, N, Karjalainen, J, Willemsen, G, Gharib, S A, Zgaga, L, Mihailov, E, Stone, K L, Campbell, H, Brouwer, R W, Demirkan, A, Isaacs, A, Dogas, Z, Marciante, K D, Campbell, S, Borovecki, F, Luik, A I, Li, M, Hottenga, J J, Huffman, J E, van den Hout, M C G N, Cummings, S R, Aulchenko, Y S, Gehrman, P R, Uitterlinden, A G, Wichmann, H-E, Muller-Nurasyid, M, Fehrmann, R S N, Montgomery, G W, Hofman, A, Kao, W H L, Oostra, B A, Wright, A F, Vink, J M, Wilson, J F, Pramstaller, P P, Hicks, A A, Polasek, O, Punjabi, N M, Redline, S, Psaty, B M, Heath, A C, Merrow, M, Tranah, G J, Gottlieb, D J, Boomsma, D I, Martin, N G, Rudan, I, Tiemeier, H, van IJcken, W F J, Penninx, B W, Metspalu, A, Meitinger, T, Franke, L, Roenneberg, T & van Duijn, C M 2016, ' Genetic variants in RBFOX3 are associated with sleep latency ', European Journal of Human Genetics, vol. 24, no. 10, pp. 1488-1495 . https://doi.org/10.1038/ejhg.2016.31
European Journal of Human Genetics, 24, 1488-1495
European Journal of Human Genetics, 24, 10, pp. 1488-1495
EUROPEAN JOURNAL OF HUMAN GENETICS
Eur. J. Hum. Genet. 24, 1488-1495 (2016)
Amin, N, Allebrandt, K V, Spek, A, Müller-Myhsok, B, Hek, K, Teder-Laving, M, Hayward, C, Esko, T, van Mill, J G, Mbarek, H, Watson, N F, Melville, S A, Del Greco, M F, Byrne, E M, Oole, E, Kolcic, I, Chen, T, Evans, D S, Coresh, J, Vogelzangs, N, Karjalainen, J, Willemsen, G, Gharib, S A, Zgaga, L, Mihailov, E, Stone, K L, Campbell, H, Brouwer, R W W, Demirkan, A, Isaacs, A, Dogas, Z, Marciante, K, Campbell, S, Borovecki, F, Luik, A I, Li, M, Hottenga, J J, Huffman, J E, van den Hout, M C G N, Cummings, S R, Aulchenko, Y S, Gehrman, P R, Uitterlinden, A G, Wichmann, H E, Müller-Nurasyid, M, Fehrmann, R S N, Montgomery, G W, Hofman, A, Hong, W, Kao, L, Oostra, B A, Wright, A F, Vink, J M, Wilson, J F, Pramstaller, P P, Hicks, A A, Polasek, O, Punjabi, N M, Redline, S, Psaty, B M, Heath, A C, Merrow, M, Tranah, G J, Gottlieb, D J, Boomsma, D I, Martin, N G, Rudan, I, Tiemeier, H, van Ijcken, W F J, Penninx, B W J H, Metspalu, A, Meitinger, T, Franke, L, Roenneberg, T & van Duijn, C M 2016, ' Genetic variants in RBFOX3 are associated with sleep latency ', European Journal of Human Genetics, vol. 24, no. 10, pp. 1488-1495 . https://doi.org/10.1038/ejhg.2016.31
European Journal of Human Genetics
Time to fall asleep (sleep latency) is a major determinant of sleep quality. Chronic, long sleep latency is a major characteristic of sleep-onset insomnia and/or delayed sleep phase syndrome. In this study we aimed to discover common polymorphisms th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15e019588fe0e67cecaae1393586b60
https://research.rug.nl/en/publications/18161e92-3b6d-4d78-92ac-a40e0b26044c
https://research.rug.nl/en/publications/18161e92-3b6d-4d78-92ac-a40e0b26044c
Autor:
Charalambos P. Kyriacou, Caroline Hayward, C M van Duijn, Till Roenneberg, Karla V. Allebrandt, Nicole Vogelzangs, Tõnu Esko, A. C. J. W. Janssens, J. van Mill, James F. Wilson, Peter Lichtner, Harry Campbell, Igor Rudan, R. V. D. M. Azevedo, Bertram Mueller-Myhsok, Edward W. Green, Zoran Dogas, Andres Metspalu, Martha Merrow, H-E Wichmann, Scott A. Melville, Ben A. Oostra, Brenda W.J.H. Penninx, Maris Teder-Laving, Najaf Amin, Thomas Meitinger, Andrew A. Hicks, Peter P. Pramstaller
Publikováno v:
Allebrandt, K V, Amin, N, Muller-Myhsok, B, Esko, T, Teder-Laving, M, Azevedo, R V D M, Hayward, C, van Mill, J G, Vogelzangs, N, Green, E W, Melville, S A, Lichtner, P, Wichmann, H E, Oostra, B A, Janssens, A C J W, Campbell, H, Wilson, J F, Hicks, A A, Pramstaller, P P, Dogas, Z, Rudan, I, Merrow, M, Penninx, B W J H, Kyriacou, C P, Metspalu, A, van Duijn, C M, Meitinger, T & Roenneberg, T 2013, ' A K-ATP channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila ', Molecular Psychiatry, vol. 18, no. 1, pp. 122-132 . https://doi.org/10.1038/mp.2011.142
Molecular Psychiatry, 18(1), 122-132. Nature Publishing Group
Mol. Psychiatry 18, 122-132 (2013)
Molecular Psychiatry, 18(1), 122-132. Nature Publishing Group
Mol. Psychiatry 18, 122-132 (2013)
Humans sleep approximately a third of their lifetime. The observation that individuals with either long or short sleep duration show associations with metabolic syndrome and psychiatric disorders suggests that the length of sleep is adaptive. Althoug