Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Karla R. Wiehagen"'
Autor:
Raluca I. Verona, Michael Quigley, Iqbal S. Grewal, Szeman Ruby Chan, Andressa A. Smith, Douglas H. Yamada, Natasha M. Girgis, Karla R. Wiehagen
S1. CSF-1R is most highly expressed on TAMs in CT26 tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24096d076cb8d0fa410c8b09b210b6a4
https://doi.org/10.1158/2326-6066.22537334
https://doi.org/10.1158/2326-6066.22537334
Autor:
Raluca I. Verona, Michael Quigley, Iqbal S. Grewal, Szeman Ruby Chan, Andressa A. Smith, Douglas H. Yamada, Natasha M. Girgis, Karla R. Wiehagen
Efficacious antitumor immune responses must overcome multiple suppressive mechanisms in the tumor microenvironment to control cancer progression. In this study, we demonstrate that dual targeting of suppressive myeloid populations by inhibiting CSF-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a2afae30831b7f4b1fa446dc0c33a1d
https://doi.org/10.1158/2326-6066.c.6548396.v1
https://doi.org/10.1158/2326-6066.c.6548396.v1
Autor:
Raluca I. Verona, Michael Quigley, Iqbal S. Grewal, Szeman Ruby Chan, Andressa A. Smith, Douglas H. Yamada, Natasha M. Girgis, Karla R. Wiehagen
S4. The cytokine milieu is more inflammatory in anti-CD40 and combination treated tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183f3ad792a5099213450bac80e39499
https://doi.org/10.1158/2326-6066.22537325.v1
https://doi.org/10.1158/2326-6066.22537325.v1
Autor:
Raluca I. Verona, Michael Quigley, Iqbal S. Grewal, Szeman Ruby Chan, Andressa A. Smith, Douglas H. Yamada, Natasha M. Girgis, Karla R. Wiehagen
S3. Increased frequencies of effector CD8+ T cells in dLN and tumor after combination treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20208149bd6a96ff9a8bd560a1136130
https://doi.org/10.1158/2326-6066.22537328.v1
https://doi.org/10.1158/2326-6066.22537328.v1
Autor:
Raluca I. Verona, Michael Quigley, Iqbal S. Grewal, Szeman Ruby Chan, Andressa A. Smith, Douglas H. Yamada, Natasha M. Girgis, Karla R. Wiehagen
S2. CD45+ Immune infiltrate varies with immunotherapy, while frequencies of CD11b+ myeloid population are not significantly altered.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af55fc89e2f3f30d29fff88d25126804
https://doi.org/10.1158/2326-6066.22537331.v1
https://doi.org/10.1158/2326-6066.22537331.v1
Autor:
Cynthia A. Zahnow, Robert A. Casero, Stephen B. Baylin, Meredith L. Stone, Jackson R. Foley, Kurtis E. Bachman, Karla R. Wiehagen, Cassandra E. Holbert, Matthew Dunworth, Stephen M. Brown, Meghan Travers
Although ovarian cancer has a low incidence rate, it remains the most deadly gynecologic malignancy. Previous work has demonstrated that the DNMTi 5-Azacytidine (5AZA-C) activates type I interferon signaling to increase IFNγ+ T cells and natural kil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce4be1bc7f2b0b5d91d58f1fd6f863a0
https://doi.org/10.1158/0008-5472.c.6510837.v1
https://doi.org/10.1158/0008-5472.c.6510837.v1
Autor:
Cynthia A. Zahnow, Robert A. Casero, Stephen B. Baylin, Meredith L. Stone, Jackson R. Foley, Kurtis E. Bachman, Karla R. Wiehagen, Cassandra E. Holbert, Matthew Dunworth, Stephen M. Brown, Meghan Travers
Supplementary data including polyamine levels, addition of anti-PD-1 to therapy, and flow cytometry plots.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387a8abf8c0d525ec7845d74e8b2e651
https://doi.org/10.1158/0008-5472.22421085.v1
https://doi.org/10.1158/0008-5472.22421085.v1
Autor:
Meredith L. Stone, Kurtis E. Bachman, Cynthia A. Zahnow, Stephen B. Baylin, Jackson R. Foley, Matthew Dunworth, Cassandra E. Holbert, Karla R. Wiehagen, Robert A. Casero, Meghan Travers, Stephen M. Brown
Publikováno v:
Cancer Res
Although ovarian cancer has a low incidence rate, it remains the most deadly gynecologic malignancy. Previous work has demonstrated that the DNMTi 5-Azacytidine (5AZA-C) activates type I interferon signaling to increase IFNγ+ T cells and natural kil
Autor:
Karla R Wiehagen, Evann Corbo-Rodgers, Shanru Li, Elizabeth S Staub, Christopher A Hunter, Edward E Morrisey, Jonathan S Maltzman
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42273 (2012)
Transcription factors regulate T cell fates at every stage of development and differentiation. Members of the Foxp family of forkhead transcription factors are essential for normal T lineage development; Foxp3 is required for T regulatory cell genera
Externí odkaz:
https://doaj.org/article/8f68866351aa47f89c4445fa7099f94d
Autor:
Michael Quigley, Douglas H. Yamada, Raluca Verona, Szeman Ruby Chan, Andressa Smith, Natasha M. Girgis, Iqbal S. Grewal, Karla R. Wiehagen
Publikováno v:
Cancer Immunology Research. 5:1109-1121
Efficacious antitumor immune responses must overcome multiple suppressive mechanisms in the tumor microenvironment to control cancer progression. In this study, we demonstrate that dual targeting of suppressive myeloid populations by inhibiting CSF-1