Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Karla R, Kaun"'
Autor:
Kristin M Scaplen, Mustafa Talay, John D Fisher, Raphael Cohn, Altar Sorkaç, Yoshi Aso, Gilad Barnea, Karla R Kaun
Publikováno v:
eLife, Vol 10 (2021)
The mushroom body (MB) is a well-characterized associative memory structure within the Drosophila brain. Analyzing MB connectivity using multiple approaches is critical for understanding the functional implications of this structure. Using the geneti
Externí odkaz:
https://doaj.org/article/2d2c90be130240309c7463a2364c6d2a
Autor:
Kristin M Scaplen, Mustafa Talay, Kavin M Nunez, Sarah Salamon, Amanda G Waterman, Sydney Gang, Sophia L Song, Gilad Barnea, Karla R Kaun
Publikováno v:
eLife, Vol 9 (2020)
A powerful feature of adaptive memory is its inherent flexibility. Alcohol and other addictive substances can remold neural circuits important for memory to reduce this flexibility. However, the mechanism through which pertinent circuits are selected
Externí odkaz:
https://doaj.org/article/9b9d022399514c729a4713e53f4eebd9
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Alcohol use disorder generates devastating social, medical and economic burdens, making it a major global health issue. The persistent nature of memories associated with intoxication experiences often induces cravings and triggers relapse in recoveri
Externí odkaz:
https://doaj.org/article/f1f95f8b90a8400997058b8d2969ba3a
Autor:
John Hernandez, Karla R. Kaun
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(29)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c121d0226966cb0eb27173f49bb61c3
https://pubmed.ncbi.nlm.nih.gov/35969795
https://pubmed.ncbi.nlm.nih.gov/35969795
Publikováno v:
Genetics. 215:103-116
Cues associated with intoxication can elicit cravings for alcohol, leading to increased consumption and relapse in people recovering from alcohol use disorder. Petruccelli et al. employed genetic tools in... Repeated alcohol experiences can produce l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6acc9482072b4f5c0d16c8fb41c108b
https://doi.org/10.1534/genetics.120.303101
https://doi.org/10.1534/genetics.120.303101
Publikováno v:
Genes; Volume 13; Issue 6; Pages: 1045
Opiate/opioid use disorder (OUD) is a chronic relapsing brain disorder that has increased in prevalence in the last two decades in the United States. Understanding the molecular correlates of OUD may provide key insights into the pathophysiology of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7682f30b806ab1385789a5854fa655b7
https://pubmed.ncbi.nlm.nih.gov/35741807
https://pubmed.ncbi.nlm.nih.gov/35741807
Autor:
Karla R. Kaun, Reza Azanchi, Nicholas J. Mei, Sophia L. Song, Kristin M. Scaplen, Hayley A. Bounds
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports
Scientific Reports
Recent advances in neurogenetics have highlighted Drosophila melanogaster as an exciting model to study neural circuit dynamics and complex behavior. Automated tracking methods have facilitated the study of complex behaviors via high throughput behav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e0b67f7befc04b07d079ac013d3fcf
http://link.springer.com/article/10.1038/s41598-019-40952-5
http://link.springer.com/article/10.1038/s41598-019-40952-5
Autor:
Yoshinori Aso, Divya Sitaraman, Toshiharu Ichinose, Karla R Kaun, Katrin Vogt, Ghislain Belliart-Guérin, Pierre-Yves Plaçais, Alice A Robie, Nobuhiro Yamagata, Christopher Schnaitmann, William J Rowell, Rebecca M Johnston, Teri-T B Ngo, Nan Chen, Wyatt Korff, Michael N Nitabach, Ulrike Heberlein, Thomas Preat, Kristin M Branson, Hiromu Tanimoto, Gerald M Rubin
Publikováno v:
eLife, Vol 3 (2014)
Animals discriminate stimuli, learn their predictive value and use this knowledge to modify their behavior. In Drosophila, the mushroom body (MB) plays a key role in these processes. Sensory stimuli are sparsely represented by ∼2000 Kenyon cells, w
Externí odkaz:
https://doaj.org/article/80cc4fc89fc9426e8ebf8f85444746e7
Publikováno v:
J Neurogenet
The genetic basis of alcohol use disorder (AUD) is complex. Understanding how natural genetic variation contributes to alcohol phenotypes can help us identify and understand the genetic basis of AUD. Recently, a single nucleotide polymorphism in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d1759c8781a5fbac1c05252ac77f37
https://europepmc.org/articles/PMC9215342/
https://europepmc.org/articles/PMC9215342/
The genetic basis of alcohol use disorder (AUD) is complex. Understanding how natural genetic variation contributes to alcohol phenotypes can help identify mechanisms underlying the genetic contribution of AUD. Recently, a single nucleotide polymorph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8a8ae742939e72f6165a7d8a6bfd8b9
https://doi.org/10.1101/2021.02.09.430533
https://doi.org/10.1101/2021.02.09.430533