Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Karla Moran-Santibanez"'
Autor:
Jessica D. Hess, Luca H. Macias, Denisse A. Gutierrez, Karla Moran-Santibanez, Lisett Contreras, Stephanie Medina, Paulina J. Villanueva, Robert A. Kirken, Armando Varela-Ramirez, Manuel L. Penichet, Renato J. Aguilera
Publikováno v:
Biology, Vol 11, Iss 6, p 930 (2022)
In recent years, the thienopyrazole moiety has emerged as a pharmacologically active scaffold with antitumoral and kinase inhibitory activity. In this study, high-throughput screening of 2000 small molecules obtained from the ChemBridge DIVERset libr
Externí odkaz:
https://doaj.org/article/ecd0ac3c2f914b6c81921427813e37b2
Autor:
Denisse A. Gutierrez, Lisett Contreras, Paulina J. Villanueva, Edgar A. Borrego, Karla Morán-Santibañez, Jessica D. Hess, Rebecca DeJesus, Manuel Larragoity, Ana P. Betancourt, Jonathon E. Mohl, Elisa Robles-Escajeda, Khodeza Begum, Sourav Roy, Robert A. Kirken, Armando Varela-Ramirez, Renato J. Aguilera
Publikováno v:
Cells, Vol 11, Iss 2, p 254 (2022)
In this study, we identified a novel pyrazole-based derivative (P3C) that displayed potent cytotoxicity against 27 human cancer cell lines derived from different tissue origins with 50% cytotoxic concentrations (CC50) in the low micromolar and nanomo
Externí odkaz:
https://doaj.org/article/5cbd8028ab8145fe8e7fc335095f7d64
Autor:
Karla Morán-Santibañez, Abimael H. Vasquez, Armando Varela-Ramirez, Veronica Henderson, Janae Sweeney, Valerie Odero-Marah, Karine Fenelon, Rachid Skouta
Publikováno v:
Antioxidants, Vol 8, Iss 10, p 427 (2019)
Creosote bush (Larrea tridentata; LT) leaves extracts were tested for their potential efficacy to mitigate cellular oxidative stress on human SH-SY5Y cells. Here, the differential nuclear staining assay, a bioimager system, and flow cytometric protoc
Externí odkaz:
https://doaj.org/article/7957a9106f0b42f9b8077a2a0c201ab9
Autor:
Karla Morán-Santibañez, Mario A. Peña-Hernández, Lucia Elizabeth Cruz-Suárez, Denis Ricque-Marie, Rachid Skouta, Abimael H. Vasquez, Cristina Rodríguez-Padilla, Laura M. Trejo-Avila
Publikováno v:
Viruses, Vol 10, Iss 9, p 465 (2018)
Although preventable by vaccination, Measles still causes thousands of deaths among young children worldwide. The discovery of new antivirals is a good approach to control new outbreaks that cause such death. In this study, we tested the antiviral ac
Externí odkaz:
https://doaj.org/article/7f892b99cbd4487bbee8410a4f5c3a7a
Autor:
Rachid Skouta, Karla Morán-Santibañez, Carlos A. Valenzuela, Abimael H. Vasquez, Karine Fenelon
Publikováno v:
Molecules, Vol 23, Iss 7, p 1826 (2018)
Oxidative stress has been linked to neurodegenerative diseases such as Huntington’s, Parkinson’s, Alzheimer’s and amyotrophic lateral sclerosis diseases. Larrea tridentata (LT) also known as Creosote Bush is an evergreen shrub found in the Chih
Externí odkaz:
https://doaj.org/article/7231d2b7fe27493db4d0c17ad0234fe5