Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Karla Misselbeck"'
Autor:
Karla Misselbeck, Silvia Parolo, Francesca Lorenzini, Valeria Savoca, Lorena Leonardelli, Pranami Bora, Melissa J. Morine, Maria Caterina Mione, Enrico Domenici, Corrado Priami
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Metabolic syndrome is characterized by complex phenotypes that increases the risk of cardiovascular disease and type 2 diabetes. Here the authors’ integrative network analysis suggests BTK inhibitor ibrutinib to be a promising treatment through its
Externí odkaz:
https://doaj.org/article/f96705c65bfd49bc85730e82b064dab7
Autor:
Karla Misselbeck, Luca Marchetti, Martha S. Field, Marco Scotti, Corrado Priami, Patrick J. Stover
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Folate-mediated one-carbon metabolism (FOCM) is an interconnected network of metabolic pathways, including those required for the de novo synthesis of dTMP and purine nucleotides and for remethylation of homocysteine to methionine. Mouse mod
Externí odkaz:
https://doaj.org/article/ee1ba554942b4b4387b3ac00e7d20fca
Autor:
Silvia Parolo, Luca Marchetti, Mario Lauria, Karla Misselbeck, Marie-Pier Scott-Boyer, Laura Caberlotto, Corrado Priami
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194225 (2018)
Although the genetic basis of Duchenne muscular dystrophy has been known for almost thirty years, the cellular and molecular mechanisms characterizing the disease are not completely understood and an efficacious treatment remains to be developed. In
Externí odkaz:
https://doaj.org/article/fb8c88370abc4b8a87014b7b461c2df4
Autor:
Corrado Priami, Melissa J. Morine, Valeria Savoca, Karla Misselbeck, Silvia Parolo, Pranami Bora, Maria Caterina Mione, Francesca Lorenzini, Enrico Domenici, Lorena Leonardelli
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Metabolic syndrome is a pathological condition characterized by obesity, hyperglycemia, hypertension, elevated levels of triglycerides and low levels of high-density lipoprotein cholesterol that increase cardiovascular disease risk and type 2 diabete
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
In folate-mediated one-carbon metabolism (FOCM), 5-formyltetrahydrofolate (5fTHF), a one-carbon substituted tetrahydrofolate (THF) vitamer, acts as an intracellular storage form of folate and as an inhibitor of the folate-dependent enzymes phosphorib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25355e8494dd3bd3f9cededbc9b3d10c
http://hdl.handle.net/11572/326026
http://hdl.handle.net/11572/326026
Autor:
Laura Caberlotto, Silvia Parolo, Corrado Priami, Marie-Pier Scott-Boyer, Luca Marchetti, Mario Lauria, Karla Misselbeck
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0194225 (2018)
PLOS ONE
PLoS ONE, Vol 13, Iss 3, p e0194225 (2018)
PLOS ONE
Although the genetic basis of Duchenne muscular dystrophy has been known for almost thirty years, the cellular and molecular mechanisms characterizing the disease are not completely understood and an efficacious treatment remains to be developed. In