Zobrazeno 1 - 10
of 810
pro vyhledávání: '"Karla L. Miller"'
Autor:
Nicole Eichert, Jordan DeKraker, Amy F. D. Howard, Istvan N. Huszar, Silei Zhu, Jérôme Sallet, Karla L. Miller, Rogier B. Mars, Saad Jbabdi, Boris C. Bernhardt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract While the hippocampus is key for human cognitive abilities, it is also a phylogenetically old cortex and paradoxically considered evolutionarily preserved. Here, we introduce a comparative framework to quantify preservation and reconfigurati
Externí odkaz:
https://doaj.org/article/c8220ed37d814351b29baefa91a38ab3
Autor:
Juan M. Godoy-Corchuelo, Zeinab Ali, Jose M. Brito Armas, Aurea B. Martins-Bach, Irene García-Toledo, Luis C. Fernández-Beltrán, Juan I. López-Carbonero, Pablo Bascuñana, Shoshana Spring, Irene Jimenez-Coca, Ramón A. Muñoz de Bustillo Alfaro, Maria J. Sánchez-Barrena, Remya R. Nair, Brian J. Nieman, Jason P. Lerch, Karla L. Miller, Hande P. Ozdinler, Elizabeth M.C. Fisher, Thomas J. Cunningham, Abraham Acevedo-Arozena, Silvia Corrochano
Publikováno v:
Neurobiology of Disease, Vol 193, Iss , Pp 106437- (2024)
TDP-43 pathology is found in several neurodegenerative disorders, collectively referred to as “TDP-43 proteinopathies”. Aggregates of TDP-43 are present in the brains and spinal cords of >97% of amyotrophic lateral sclerosis (ALS), and in brains
Externí odkaz:
https://doaj.org/article/76599e797bbd49ac8a63e0a6d72160dc
Autor:
Amy F. D. Howard, Istvan N. Huszar, Adele Smart, Michiel Cottaar, Greg Daubney, Taylor Hanayik, Alexandre A. Khrapitchev, Rogier B. Mars, Jeroen Mollink, Connor Scott, Nicola R. Sibson, Jerome Sallet, Saad Jbabdi, Karla L. Miller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Understanding brain structure and function often requires combining data across different modalities and scales to link microscale cellular structures to macroscale features of whole brain organisation. Here we introduce the BigMac dataset,
Externí odkaz:
https://doaj.org/article/106cfe8ccd9d47aba3d111a96d0102fd
Autor:
Zeinab Ali, Juan M. Godoy-Corchuelo, Aurea B. Martins-Bach, Irene Garcia-Toledo, Luis C. Fernández-Beltrán, Remya R. Nair, Shoshana Spring, Brian J. Nieman, Irene Jimenez-Coca, Rasneer S. Bains, Hamish Forrest, Jason P. Lerch, Karla L. Miller, Elizabeth M. C. Fisher, Thomas J. Cunningham, Silvia Corrochano
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/3f0a2c5de56a43eca3efee6113651e7a
Autor:
Vaanathi Sundaresan, Christoph Arthofer, Giovanna Zamboni, Andrew G. Murchison, Robert A. Dineen, Peter M. Rothwell, Dorothee P. Auer, Chaoyue Wang, Karla L. Miller, Benjamin C. Tendler, Fidel Alfaro-Almagro, Stamatios N. Sotiropoulos, Nikola Sprigg, Ludovica Griffanti, Mark Jenkinson
Publikováno v:
Frontiers in Neuroinformatics, Vol 17 (2023)
IntroductionCerebral microbleeds (CMBs) are associated with white matter damage, and various neurodegenerative and cerebrovascular diseases. CMBs occur as small, circular hypointense lesions on T2*-weighted gradient recalled echo (GRE) and susceptibi
Externí odkaz:
https://doaj.org/article/ee9b9d7ea4384217946165ef86d8997d
Autor:
Florence Rawlings-Mortimer, Alberto Lazari, Cristiana Tisca, Mohamed Tachrount, Aurea B. Martins-Bach, Karla L. Miller, Jason P. Lerch, Heidi Johansen-Berg
Publikováno v:
Frontiers in Systems Neuroscience, Vol 17 (2023)
Introduction: 7,8-dihydroxyflavone (7,8-DHF) is a low molecular weight compound that can cross the blood brain barrier and has been implicated in numerous functions and behaviours. It is thought to have neuroprotective capability and has been shown t
Externí odkaz:
https://doaj.org/article/903a82439b1c499892b968bc77e70db7
Autor:
Anya Topiwala, Thomas E. Nichols, Logan Z. J. Williams, Emma C. Robinson, Fidel Alfaro-Almagro, Bernd Taschler, Chaoyue Wang, Christopher P. Nelson, Karla L. Miller, Veryan Codd, Nilesh J. Samani, Stephen M. Smith
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
Telomeres form protective caps at the ends of chromosomes, and their attrition is a marker of biological aging. Short telomeres are associated with an increased risk of neurological and psychiatric disorders including dementia. The mechanism underlyi
Externí odkaz:
https://doaj.org/article/e413676e4ee947c38d8150c642ce29a5
Autor:
Istvan N. Huszar, Menuka Pallebage-Gamarallage, Sarah Bangerter-Christensen, Hannah Brooks, Sean Fitzgibbon, Sean Foxley, Marlies Hiemstra, Amy F.D. Howard, Saad Jbabdi, Daniel Z.L. Kor, Anna Leonte, Jeroen Mollink, Adele Smart, Benjamin C. Tendler, Martin R. Turner, Olaf Ansorge, Karla L. Miller, Mark Jenkinson
Publikováno v:
NeuroImage, Vol 265, Iss , Pp 119792- (2023)
Background: Accurate registration between microscopy and MRI data is necessary for validating imaging biomarkers against neuropathology, and to disentangle complex signal dependencies in microstructural MRI. Existing registration methods often rely o
Externí odkaz:
https://doaj.org/article/267f63747d204042b30e3e21b044b8fb
Autor:
Daniel Z.L. Kor, Saad Jbabdi, Istvan N. Huszar, Jeroen Mollink, Benjamin C. Tendler, Sean Foxley, Chaoyue Wang, Connor Scott, Adele Smart, Olaf Ansorge, Menuka Pallebage-Gamarallage, Karla L. Miller, Amy F.D. Howard
Publikováno v:
NeuroImage, Vol 264, Iss , Pp 119726- (2022)
The acquisition of MRI and histology in the same post-mortem tissue sample enables direct correlation between MRI and histologically-derived parameters. However, there still lacks a standardised automated pipeline to process histology data, with most
Externí odkaz:
https://doaj.org/article/f5ef11d9b2664f16ba61b7dd89eb334b
Publikováno v:
JBMR Plus, Vol 6, Iss 10, Pp n/a-n/a (2022)
ABSTRACT A primary osteoporosis prevention program using a virtual bone health team (BHT) was implemented to comanage the care of rural veterans in the Mountain West region of the United States. The BHT identified, screened, and treated rural veteran
Externí odkaz:
https://doaj.org/article/e4adee3edff44e4baf9443cf09ea8f27