Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Karla K Rodgers"'
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216137 (2019)
RAG2 of the V(D)J recombinase is essential for lymphocyte development. Within the RAG2 noncore region is a plant homeodomain (PHD) that interacts with the modified histone H3K4me3, and this interaction is important for relieving inhibition of the RAG
Externí odkaz:
https://doaj.org/article/2a2d99dc63b14c308a30b44ece522a6f
Publikováno v:
ACS Omega, Vol 8, Iss 38, Pp 34206-34214 (2023)
Externí odkaz:
https://doaj.org/article/e13171e2a91d4a79a9762a24f7af620e
Publikováno v:
Nucleic acids research. 50(20)
In the adaptive immune system, V(D)J recombination initiates the production of a diverse antigen receptor repertoire in developing B and T cells. Recombination activating proteins, RAG1 and RAG2 (RAG1/2), catalyze V(D)J recombination by cleaving adja
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad04abe06ba96f9e43e1912c9740fba
https://pubmed.ncbi.nlm.nih.gov/36370096
https://pubmed.ncbi.nlm.nih.gov/36370096
Autor:
Karla K. Rodgers, Gertrude Kyere-Davies, Asif Alam Chowdhury, Neha Chataut, Bhupinder Singh, Gaurav Kumar, Shanjana Awasthi, Negar S. Rahman, Jacob Beierle, Jun Xie, Vibhudutta Awasthi, Vijay Ramani
Publikováno v:
ImmunoHorizons
The TLR4-interacting SPA4 peptide suppresses inflammation. We assessed the structural and physicochemical properties and binding of SPA4 peptide to TLR4–MD2. We also studied the changes at the whole transcriptome level, cell morphology, viability,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e278c6e18db363a3871ec397fa28f4d
https://doi.org/10.4049/immunohorizons.2100067
https://doi.org/10.4049/immunohorizons.2100067
In the adaptive immune system, V(D)J recombination initiates the production of a diverse antigen receptor repertoire in developing B and T cells. Recombination activating proteins, RAG1 and RAG2 (RAG1/2), catalyze V(D)J recombination by cleaving adja
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4415492ddc87e77526d121ec8dfcd600
https://doi.org/10.1101/2021.12.03.471157
https://doi.org/10.1101/2021.12.03.471157
Autor:
Karla K. Rodgers, Walker Hoolehan
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa1fc9bb11bc09861da8888c37f6b8aa
https://doi.org/10.1096/fasebj.2021.35.s1.01534
https://doi.org/10.1096/fasebj.2021.35.s1.01534
Autor:
Destiny A Simpson, Karla K. Rodgers
Publikováno v:
The Journal of Immunology. 208:107.13-107.13
The V(D)J recombinase, composed of the recombination activating gene (RAG) proteins, RAG1 and RAG2, generate functional antigen receptor genes through the repeated generation of DNA double strand breaks and DNA repair. However, this process can lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70df4c3be92b6b45dcb87fbd40ddc971
https://doi.org/10.4049/jimmunol.208.supp.107.13
https://doi.org/10.4049/jimmunol.208.supp.107.13
Autor:
Karla K. Rodgers
Publikováno v:
Trends in Biochemical Sciences. 42:72-84
Development of the adaptive immune system is dependent on V(D)J recombination, which forms functional antigen receptor genes through rearrangement of component gene segments. The V(D)J recombinase, consisting of recombination-activating proteins RAG1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0f054e2a7bfa4c8377cab349aaf1f5
https://doi.org/10.1016/j.tibs.2016.10.003
https://doi.org/10.1016/j.tibs.2016.10.003
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216137 (2019)
PLoS ONE
PLoS ONE
RAG2 of the V(D)J recombinase is essential for lymphocyte development. Within the RAG2 noncore region is a plant homeodomain (PHD) that interacts with the modified histone H3K4me3, and this interaction is important for relieving inhibition of the RAG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb977f8cafc35853701386d84e004bf
https://doaj.org/article/2a2d99dc63b14c308a30b44ece522a6f
https://doaj.org/article/2a2d99dc63b14c308a30b44ece522a6f
Publikováno v:
The Journal of Immunology. 206:107.04-107.04
V(D)J recombination is required to establish the diversity of antigen receptors in the adaptive immune system. Recombination activating gene 2 (RAG2), a protein subunit of the nuclear V(D)J recombinase, rearranges gene segments to generate functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df16224284485afa0513e3f94f06cc04
https://doi.org/10.4049/jimmunol.206.supp.107.04
https://doi.org/10.4049/jimmunol.206.supp.107.04