Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Karla J.F. Satchell"'
Autor:
Nicole L. Inniss, Margarita Rzhetskaya, Ted Ling-Hu, Ramon Lorenzo-Redondo, Kelly E. Bachta, Karla J.F. Satchell, Judd F. Hultquist
Publikováno v:
SLAS Discovery, Vol 29, Iss 3, Pp 100145- (2024)
SARS-CoV-2 nsp13 helicase is an essential enzyme for viral replication and a promising target for antiviral drug development. This study compares the double-stranded RNA (dsRNA) unwinding activity of nsp13 and the Omicron nsp13R392C variant, which is
Externí odkaz:
https://doaj.org/article/eb32c9ea90b64b2d853170267438612d
Autor:
Taylor E. Escher, Karla J.F. Satchell
Publikováno v:
Molecular Therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c9c5f4a3321ffade66fbeb856e76007
https://doi.org/10.1016/j.ymthe.2023.03.017
https://doi.org/10.1016/j.ymthe.2023.03.017
Autor:
Vania Vidimar, Minyoung Park, Caleb K. Stubbs, Nana K. Ingram, Wenan Qiang, Shanshan Zhang, Demirkan Gursel, Roman A. Melnyk, Karla J.F. Satchell
Publikováno v:
Mol Cancer Ther
The lack of effective RAS inhibition represents a major unmet medical need in the treatment of pancreatic ductal adenocarcinoma (PDAC). Here, we investigate the anticancer activity of RRSP-DTB, an engineered biologic that cleaves the Switch I of all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0793eba7095878b7a87aa95e87cd8649
https://europepmc.org/articles/PMC9933180/
https://europepmc.org/articles/PMC9933180/
Autor:
Patricia A. Bauman, Andrew C. Doxey, Ivano Eberini, Emir Islamovic, Florence Jungo, Colton Kessenich, John Kough, Mansi Krishan, Luca Palazzolo, Laura Privalle, Chester E. Rodriguez, Karla J.F. Satchell, Andre Silvanovich, Lucilia Pereira Mouriès
Publikováno v:
Regulatory Toxicology and Pharmacology. 131:105146
On October 21-22, 2020 the HESI (Health and Environmental Sciences Institute) Protein Allergens, Toxins, and Bioinformatics Committee, and the Society of Toxicology Food Safety Specialty Section co-hosted a virtual workshop titled "From Protein Toxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c562839eab0adb66a63a0ed7c91afcf1
https://doi.org/10.1016/j.yrtph.2022.105146
https://doi.org/10.1016/j.yrtph.2022.105146