Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Karla J. Posekany"'
Autor:
Cynthia A. Kukoly, Paul P. Cook, Winifred O. Bryant, James E. deVente, Peter J. Parker, D. K. Ways, J. Hooker, Karla J. Posekany, Donald J. Fletcher
Publikováno v:
Journal of Clinical Investigation. 95:1906-1915
Increased protein kinase C (PKC) activity in malignant breast tissue and positive correlations between PKC activity and expression of a more aggressive phenotype in breast cancer cell lines suggest a role for this signal transduction pathway in the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb138d8dfa71a6b00aa2ae160728cce
https://doi.org/10.1172/jci117872
https://doi.org/10.1172/jci117872
Publikováno v:
Anticancer research. 29(6)
Expression of the immunostimulatory xenoantigen alphaGal on malignant cells is being investigated as a means to formulate anticancer vaccines. Expression methods have been limited to gene transfer using viral vectors and enzymatic manipulation. We re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d42c934c3c41e8f7c8c98a627f459ca1
https://pubmed.ncbi.nlm.nih.gov/19528506
https://pubmed.ncbi.nlm.nih.gov/19528506
Publikováno v:
Anticancer research. 24(2B)
Humans lack the gene alpha 1,3 galactosyltransferase (GalT) and instead produce abundant cytolytic antibodies against cells bearing the antigen [gal alpha1,3 gal] (alphaGal). We have previously studied humoral anti-alphaGal responses in GalT knock-ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7c1eb66e5774987ab39774c5ed2bb33
https://pubmed.ncbi.nlm.nih.gov/15161001
https://pubmed.ncbi.nlm.nih.gov/15161001
Publikováno v:
Infection and immunity. 70(11)
Naturally occurring antibodies against [Gal α-1,3-Gal] structures (anti-Gal antibodies) are the primary effectors of human hyperacute rejection (HAR) of nonhuman tissue. Unlike most mammals, humans lack a functional α-1,3-galactosyltransferase (Gal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3796e774758e6ebede87137c5ff8dadd
https://pubmed.ncbi.nlm.nih.gov/12379700
https://pubmed.ncbi.nlm.nih.gov/12379700
Autor:
George J. Pettit, Guillermina Lozano, Donald J. Fletcher, Winifred O. Bryant, Jianming Chen, D. Kirk Ways, Paul P. Cook, Cynthia A. Kukoly, James E. De Vente, Peter J. Parker, Karla J. Posekany
Protein kinase C (PKC) modulates growth, differentiation and apoptosis in a cell-specific fashion. Overexpression of PKC-alpha in MCF-7 breast cancer cells (MCF-7-PKC-alpha cell) leads to expression of a more transformed phenotype. The response of MC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52c890fd8415c3e67aa4b5add88aaed
https://europepmc.org/articles/PMC185824/
https://europepmc.org/articles/PMC185824/
Publikováno v:
Transplantation. 66:S62
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88641601de7016733dd05c57cc2566ea
https://doi.org/10.1097/00007890-199810270-00277
https://doi.org/10.1097/00007890-199810270-00277