Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Karla C S, Queiroz"'
Autor:
Nicola Frenkel, Lotte van den Bent, Paul Vulto, Silvia Bonilla García, Jeroen Hagendoorn, Carmen Rubio Alarcón, Susanna Poghosyan, Onno Kranenburg, Inne H.M. Borel Rinkes, Jamila Laoukili, Karla C. S. Queiroz
Publikováno v:
ACS Biomaterials Science & Engineering. 7:3030-3042
The lymphatic system is essential in maintaining tissue fluid homeostasis as well as antigen and immune cell transport to lymph nodes. Moreover, lymphatic vasculature plays an important role in various pathological processes, such as cancer. Fundamen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70bf879d610b90c56006a127a5c6f8f5
https://doi.org/10.1021/acsbiomaterials.0c01378
https://doi.org/10.1021/acsbiomaterials.0c01378
Autor:
Daisy Machado, Silvia M Shishido, Karla C S Queiroz, Diogo N Oliveira, Ana L C Faria, Rodrigo R Catharino, C Arnold Spek, Carmen V Ferreira
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54269 (2013)
Melanoma is one of the most aggressive skin cancers due to its high capacity to metastasize. Treatment of metastatic melanomas is challenging for clinicians, as most therapeutic agents have failed to demonstrate improved survival. Thus, new candidate
Externí odkaz:
https://doaj.org/article/7f789fe825444d7488916bb0d7db1d06
Autor:
Paula A Ferreira, Roberta R Ruela-de-Sousa, Karla C S Queiroz, Ana Carolina S Souza, Renato Milani, Ronaldo Aloise Pilli, Maikel P Peppelenbosch, Jeroen den Hertog, Carmen V Ferreira
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44312 (2012)
The development of multidrug resistance (MDR) limits the efficacy of continuous chemotherapeutic treatment in chronic myelogenous leukemia (CML). Low molecular weight protein tyrosine phosphatase (LMW-PTP) is up-regulated in several cancers and has b
Externí odkaz:
https://doaj.org/article/baf11ada3dda43aab3ca5486a6caa79c
Autor:
Karla C S Queiroz, Renato Milani, Roberta R Ruela-de-Sousa, Gwenny M Fuhler, Giselle Z Justo, Willian F Zambuzzi, Nelson Duran, Sander H Diks, C Arnold Spek, Carmen V Ferreira, Maikel P Peppelenbosch
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e45362 (2012)
It is now generally recognised that different modes of programmed cell death (PCD) are intimately linked to the cancerous process. However, the mechanism of PCD involved in cancer chemoprevention is much less clear and may be different between types
Externí odkaz:
https://doaj.org/article/59ad423b04b44b55ba702c93971bd05e
Autor:
Erik Wallinga, Lenie J. van den Broek, Jos Joore, Sacha Spelier, Henriëtte Leonore Lanz, Johnny Suijker, Luuk de Haan, Paul Vulto, Karla C. S. Queiroz
Publikováno v:
Cancer Research. 81:2777-2777
Recent clinical success of immune checkpoint inhibitors and chimeric antigen receptor T cells has highly increased the attention for the field of immunotherapy. However, identifying responders to these therapies is challenging underscoring the necess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7409b1663173b24869b9dc9800bd72ea
https://doi.org/10.1158/1538-7445.am2021-2777
https://doi.org/10.1158/1538-7445.am2021-2777
Autor:
Alessandra V S, Faria, Stefano P, Clerici, Patricia F, de Souza Oliveira, Karla C S, Queiroz, Maikel P, Peppelenbosch, Carmen V, Ferreira-Halder
Publikováno v:
Molecular and cellular biochemistry. 466(1-2)
In the last decade, several reports highlight the importance of the low molecular weight protein tyrosine phosphatase (LMWPTP) in cancer aggressiveness and resistance. Specifically, in chronic myeloid leukemia, we have reported that high expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04d2f06ae6d234b9442c9c60b74b4f76
https://pubmed.ncbi.nlm.nih.gov/32016696
https://pubmed.ncbi.nlm.nih.gov/32016696
Autor:
Else Driehuis, Hans Clevers, Karla C. S. Queiroz, Henriëtte L. Lanz, Paul Vulto, Jos Joore, Silvia Bonilla
Publikováno v:
Cancer Research. 80:2794-2794
Head and neck squamous cell carcinoma (HNSCC) cancer is a broad category of tumor types arising from the inner lining of various anatomic structures including the oral cavity, pharynx, larynx and salivary glands. Treatment often involves an intensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a050839d0346a05c2358ffd4ef4d516
https://doi.org/10.1158/1538-7445.am2020-2794
https://doi.org/10.1158/1538-7445.am2020-2794
Autor:
Katrien De Bock, Ward Heggermont, Rindert Missiaen, Stefan Vinckier, Stefan Christen, Holger Gerhardt, Jermaine Goveia, Gitte Borgers, Sarah-Maria Fendt, Karla C. S. Queiroz, Mieke Dewerchin, Annalisa Zecchin, Lucica Godde, Ulrike Bruning, Myriam Baes, Luc Schoonjans, Paul P. Van Veldhoven, Ilaria Elia, Sandra Schoors, Peter Carmeliet, Anna Rita Cantelmo, Bart Ghesquière, Guy Eelen, Sophia Y. Lunt
Publikováno v:
Nature
The metabolism of endothelial cells during vessel sprouting remains poorly studied. Here we report that endothelial loss of CPT1A, a rate-limiting enzyme of fatty acid oxidation (FAO), causes vascular sprouting defects due to impaired proliferation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b393013540c476bc781a0c2eb91d34da
https://doi.org/10.1038/nature14362
https://doi.org/10.1038/nature14362
Autor:
Carel J. M. van Noesel, Kun Shi, C. Arnold Spek, Karla C. S. Queiroz, Joris J. T. H. Roelofs, Dirk J. Richel
Publikováno v:
The Journal of Pathology. 234:398-409
Protease-activated receptor-2 (PAR-2) is a G protein-coupled receptor that functions as a cell-surface sensor for coagulation factors and other proteases associated with the tumour microenvironment. Pancreatic cancer cells express high levels of PAR-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e7ffd3d996f6f67e1cf3b26ac28e031
https://doi.org/10.1002/path.4411
https://doi.org/10.1002/path.4411
Autor:
Carel J. M. van Noesel, Karla C. S. Queiroz, JanWillem Duitman, Dick J. Richel, Kun Shi, Johanna W. Wilmink, Hella L. Aberson, C. Arnold Spek
Publikováno v:
International Journal of Cancer. 135:2294-2304
Protease activated receptor (PAR)-1 expression in tumor cells is associated with disease progression and overall survival in a variety of cancers of epithelial origin; however, the importance of PAR-1 in the tumor microenvironment remains unexplored.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79c3e2ed78eb00a0ab9af2c96b271fac
https://doi.org/10.1002/ijc.28726
https://doi.org/10.1002/ijc.28726