Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Karl-Jürgen Halbhuber"'
Autor:
Florian M. Corvinus, Carina Orth, Richard Moriggl, Svetlana A. Tsareva, Stefan Wagner, Edith B. Pfitzner, Daniela Baus, Roland Kaufman, Lukas A. Huber, Kurt Zatloukal, Hartmut Beug, Peter Öhlschläger, Alexander Schütz, Karl-Jürgen Halbhuber, Karlheinz Friedrich
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 6, Pp 545-555 (2005)
Colorectal carcinoma (CRC) is a major cause of morbidity and mortality in Western countries. It has so far been molecularly defined mainly by alterations of the Wnt pathway. We show here for the first time that aberrant activities of the signal trans
Externí odkaz:
https://doaj.org/article/01d811dc532a4aa7bc1d7367ab5b615f
Autor:
Takayuki Maruyama, Karl-Jürgen Halbhuber, Johannes Leuchtweis, Gabriel Natura, Hans-Georg Schaible, Susanne Hensellek, Annett Eitner, Frank Richter, Michael Karl Boettger, Karl-Jürgen Bär, Andrea Ebersberger, Gunther Olaf Hofmann
Publikováno v:
Proceedings of the National Academy of Sciences. 110:13648-13653
The pain mediator prostaglandin E 2 (PGE 2 ) sensitizes nociceptive pathways through EP2 and EP4 receptors, which are coupled to G s proteins and increase cAMP. However, PGE 2 also activates EP3 receptors, and the major signaling pathway of the EP3 r
Autor:
Christian Bergemann, Rudolf Hergt, Heike Zorn, Werner A. Kaiser, Karl-Jürgen Halbhuber, Ingrid Hilger, Sibylle Bremer-Streck, Melanie Kettering, Hartmut Oehring, Matthias Zeisberger
Publikováno v:
Physics in Medicine and Biology. 54:5109-5121
The aim of this study was to characterize the behaviour of cisplatin adsorbed magnetic nanoparticles (cis-MNPs) for minimal invasive cancer treatments in preliminary in vitro investigations. Cisplatin was adsorbed to magnetic nanoparticles (MNPs) by
Publikováno v:
Journal of Molecular Histology. 39:169-191
Fluorescent labeling of immuno-bound or endogenous peroxidase (PO) activity has been achieved to date by means of phenol derivatives with a low substitution degree. Here it is demonstrated that N,N-dialkylamino-styryl dyes can also act as fluorescent
Autor:
Iris Riemann, Karl-Jürgen Halbhuber, Karsten König, Barry Starcher, Navid Madershahian, Katja Schenke-Layland, Ulrich A. Stock
Publikováno v:
The Annals of Thoracic Surgery. 81:918-926
Background Transplantation of cryopreserved allografts represents a well-established valve replacement option. Despite their clinical use for more than 40 years, the integrity of the extracellular matrix (ECM) of these valves after thawing has not be
Autor:
Andreas Wiesner, Ferdinand von Eggeling, Sven Koscielny, Christian Melle, Ursula Möller, Günther Ernst, Dirk Osterloh, Bettina Schimmel, Annett Bleul, Ralf Bogumil, Karl-Jürgen Halbhuber
Publikováno v:
Cancer Research. 64:4099-4104
Biomarkers are needed to elucidate the biological background and to improve the detection of cancer. Therefore, we have analyzed laser-microdissected cryostat sections from head and neck tumors and adjacent mucosa on ProteinChip arrays. Two different
Autor:
Karl-Jürgen Halbhuber, Karsten König, Iris Riemann, Katja Schenke-Layland, Ulrich A. Stock, Florian Opitz
Publikováno v:
Matrix Biology. 23:113-125
Tissue engineering of heart valves utilizes biodegradable or metabolizable scaffolds for remodeling by seeded autologous cells. The aim of this study was to determine and compare extracellular matrix (ECM) formations, cellular phenotypes and cell loc
Autor:
Karl-Jürgen Halbhuber, Rolf Bräuer, Gisela Segond von Banchet, Karl-Jürgen Bär, Hans-Georg Schaible
Publikováno v:
Neuroscience Letters. 361:172-175
The TRPV1 receptor, previously called VR1 receptor, is a non-selective cation channel gated by capsaicin, noxious heat, protons and anandamide. The TRPV1 receptor is essential for the development of thermal hyperalgesia. The present study investigate
Autor:
Rolf Bräuer, Karl-Jürgen Halbhuber, Karl-Jürgen Bär, A Scholze, Uta Schurigt, N Stopfel, G Segond von Banchet, H.-G. Schaible
Publikováno v:
Neuroscience. 127:197-206
Somatostatin has antinociceptive effects by acting on somatostatin (sst) receptors in primary afferent neurons. Five sst receptor subtypes (sst(1-5)) have been identified. In the present study we assessed the expression and localization of the sst re
Autor:
Karl-Jürgen Halbhuber, Florian Opitz, C. Döring, F. Schirrmeister, Katja Schenke-Layland, Ulrich A. Stock, M. Gross, Th. Wahlers
Publikováno v:
Cardiovascular Research. 60:497-509
Objective: Cardiovascular tissue engineering is a novel concept to develop ideal heart valve substitutes. The objective of this study was to use decellularized porcine pulmonary valves, ovine cells and dynamic tissue culture to obtain viable and biom