Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Karl-Heinz Wiesmüller"'
Autor:
Claudia Tandler, Jonas S. Heitmann, Tanja M. Michel, Maddalena Marconato, Simon U. Jaeger, Christian M. Tegeler, Monika Denk, Marion Richter, Melek Tutku Oezbek, Yacine Maringer, Sarah M. Schroeder, Nicole Schneiderhan-Marra, Karl-Heinz Wiesmüller, Michael Bitzer, Natalia Ruetalo, Michael Schindler, Christoph Meisner, Imma Fischer, Hans-Georg Rammensee, Helmut R. Salih, Juliane S. Walz
Publikováno v:
International Journal of Infectious Diseases, Vol 139, Iss , Pp 69-77 (2024)
Objectives: T cell immunity is key for the control of viral infections including SARS-CoV-2, in particular with regard to immune memory and protection against arising genetic variants. Methods: We recently evaluated a peptide-based SARS-CoV-2 T cell
Externí odkaz:
https://doaj.org/article/c354f5fd26fd421f8230c3f45d62af98
Autor:
Jonas S. Heitmann, Claudia Tandler, Maddalena Marconato, Annika Nelde, Timorshah Habibzada, Susanne M. Rittig, Christian M. Tegeler, Yacine Maringer, Simon U. Jaeger, Monika Denk, Marion Richter, Melek T. Oezbek, Karl-Heinz Wiesmüller, Jens Bauer, Jonas Rieth, Marcel Wacker, Sarah M. Schroeder, Naomi Hoenisch Gravel, Jonas Scheid, Melanie Märklin, Annika Henrich, Boris Klimovich, Kim L. Clar, Martina Lutz, Samuel Holzmayer, Sebastian Hörber, Andreas Peter, Christoph Meisner, Imma Fischer, Markus W. Löffler, Caroline Anna Peuker, Stefan Habringer, Thorsten O. Goetze, Elke Jäger, Hans-Georg Rammensee, Helmut R. Salih, Juliane S. Walz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract T-cell immunity is central for control of COVID-19, particularly in patients incapable of mounting antibody responses. CoVac-1 is a peptide-based T-cell activator composed of SARS-CoV-2 epitopes with documented favorable safety profile and e
Externí odkaz:
https://doaj.org/article/b32dbe5fcabf453983d2e107f672acc4
Autor:
Julia Hansen, Katharina Kolbe, Inke R König, Regina Scherließ, Marie Hellfritzsch, Sven Malm, Sven Müller-Loennies, Julia Zallet, Doris Hillemann, Karl-Heinz Wiesmüller, Christian Herzmann, Julius Brandenburg, Norbert Reiling
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0265554 (2022)
BackgroundPulmonary Tuberculosis (TB) is diagnosed through sputum samples. As sputum sampling is challenging in children and cachexic patients, the development of diagnostic tests using saliva appears promising but has been discouraged due to low bac
Externí odkaz:
https://doaj.org/article/168b83c2de15477195c440bfc22ae2d9
Autor:
Hans-Georg Rammensee, Karl-Heinz Wiesmüller, P. Anoop Chandran, Henning Zelba, Elisa Rusch, Cécile Gouttefangeas, Daniel J. Kowalewski, Moreno Di Marco, Sebastian P. Haen, Juliane S. Walz, Yamel Cardona Gloria, Johanna Bödder, Jill-Marie Schertel, Antje Tunger, Luise Müller, Maximilian Kießler, Rebekka Wehner, Marc Schmitz, Meike Jakobi, Nicole Schneiderhan-Marra, Reinhild Klein, Karoline Laske, Kerstin Artzner, Linus Backert, Heiko Schuster, Johannes Schwenck, Alexander N. R. Weber, Bernd J. Pichler, Manfred Kneilling, Christian la Fougère, Stephan Forchhammer, Gisela Metzler, Jürgen Bauer, Benjamin Weide, Wilfried Schippert, Stefan Stevanović, Markus W. Löffler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract Background We previously showed that the bacterial lipopeptide Pam3Cys-Ser-Ser, meanwhile established as a toll-like receptor (TLR) 1/2 ligand, acts as a strong adjuvant for the induction of virus specific CD8+ T cells in mice, when covalent
Externí odkaz:
https://doaj.org/article/cc3a16412b7c49e5953df66f2cd4dccd
Publikováno v:
Neurology Research International, Vol 2019 (2019)
The human acetylcholine receptor (AChR) is well characterized as the target antigen in myasthenia gravis (MG). Pathogenic antibody responses against the AChR alpha-chain have been investigated extensively and are of diagnostic and prognostic value. H
Externí odkaz:
https://doaj.org/article/ec8e18f7567d4c68bb0e099374afcec1
Autor:
Hans-Georg Rammensee, Cécile Gouttefangeas, Sonja Heidu, Reinhild Klein, Beate Preuß, Juliane Sarah Walz, Annika Nelde, Sebastian P. Haen, Michael Reth, Jianying Yang, Ghazaleh Tabatabai, Hans Bösmüller, Helen Hoffmann, Michael Schindler, Oliver Planz, Karl-Heinz Wiesmüller, Markus W. Löffler
Publikováno v:
Vaccines, Vol 9, Iss 5, p 428 (2021)
We describe the results of two vaccinations of a self-experimenting healthy volunteer with SARS-CoV-2-derived peptides performed in March and April 2020, respectively. The first set of peptides contained eight peptides predicted to bind to the indivi
Externí odkaz:
https://doaj.org/article/1fb9244aa47644348c0c213da3a5c238
Autor:
Lena Heinbockel, Günther Weindl, Wilmar Correa, Julius Brandenburg, Norbert Reiling, Karl-Heinz Wiesmüller, Tobias Schürholz, Thomas Gutsmann, Guillermo Martinez de Tejada, Karl Mauss, Klaus Brandenburg
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1465 (2021)
The polypeptide Pep19-2.5 (Aspidasept®) has been described to act efficiently against infection-inducing bacteria by binding and neutralizing their most potent toxins, i.e., lipopolysaccharides (LPS) and lipoproteins/peptides (LP), independent of th
Externí odkaz:
https://doaj.org/article/5fd5cdcc72b340149e135be13f2ec869
Autor:
Claudia Frick, Stefan Fink, Dominik Schmidbauer, Francis Rousset, Holger Eickhoff, Anke Tropitzsch, Benedikt Kramer, Pascal Senn, Rudolf Glueckert, Helge Rask-Andersen, Karl-Heinz Wiesmüller, Hubert Löwenheim, Marcus Müller
Publikováno v:
Brain Sciences, Vol 10, Iss 9, p 580 (2020)
Background: The spatial gap between cochlear implants (CIs) and the auditory nerve limits frequency selectivity as large populations of spiral ganglion neurons (SGNs) are electrically stimulated synchronously. To improve CI performance, a possible st
Externí odkaz:
https://doaj.org/article/67d4f6d839774552a1c507b0d2e8e9a7
Autor:
Juliane Walz, Jonas Heitmann, Claudia Tandler, Maddalena Marconato, Timursah Habibzade, Susanne Rittig, Christian Tegeler, Annika Nelde, Yacine Maringer, Simon Jäger, Monika Denk, Marion Richter, Melek Oezbek, Karl-Heinz Wiesmüller, Jens Bauer, Jonas Rieth, Marcel Wacker, Sarah Schroeder, Naomi Hoenisch Gravel, Melanie Märklin, Annika Henrich, Boris Klimovich, Kim Clar, Martina Lutz, Samuel Holzmayer, Sebastian Hoerber, Andreas Peter, Christoph Meisner, Imma Fischer, Markus Löffler, Caroline Peuker, Stefan Habringer, Thorsten Goetze, Elke Jäger, Hans-Georg Rammensee, Helmut Salih
T-cell immunity is central for the control of COVID-19, in particular in patients incapable to mount a humoral immune response. We previously reported on the favorable safety profile and efficacy in terms of induction of SARS-CoV-2-specific T-cell re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11dacecc552fc88bf0c7d34ea2030f3a
https://doi.org/10.21203/rs.3.rs-1693355/v1
https://doi.org/10.21203/rs.3.rs-1693355/v1
Autor:
Ute Wank, Wolfram Sterry, Jürgen Lademann, Peter Walden, Karl-Heinz Wiesmüller, Lars Dähne, Heike Richter, Alexa Patzelt
Publikováno v:
Pharmaceutics, Vol 3, Iss 2, Pp 307-314 (2011)
Recently, it has been demonstrated that particulate substances penetrate preferentially into the hair follicles and that the penetration depth depends on the particle size. In the present study, the influence of the vehicle of the particulate substan
Externí odkaz:
https://doaj.org/article/665eb8b724ae480a84211062095b0900