Zobrazeno 1 - 10
of 74 671
pro vyhledávání: '"Karl-Heinz"'
A comprehensive IDA and SWATH-DIA Lipidomics and Metabolomics dataset: SARS-CoV-2 case control study
Autor:
Ammar Tahir, Agnes Draxler, Tamara Stelzer, Amelie Blaschke, Brenda Laky, Marton Széll, Jessica Binar, Viktoria Bartak, Laura Bragagna, Lina Maqboul, Theresa Herzog, Rainer Thell, Karl-Heinz Wagner
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-12 (2024)
Abstract A significant hurdle in untargeted lipid/metabolomics research lies in the absence of reliable, cross-validated spectral libraries, leading to a considerable portion of LC-MS features being labeled as unknowns. Despite continuous advancement
Externí odkaz:
https://doaj.org/article/3b30a79c33ff4ac695675dee8cbaa6ba
Autor:
Lars Mohren, Friedrich Erdlenbruch, Elsa Leitão, Fabian Kilpert, G. Sebastian Hönes, Sabine Kaya, Christopher Schröder, Andreas Thieme, Marc Sturm, Joohyun Park, Agatha Schlüter, Montserrat Ruiz, Moisés Morales de la Prida, Carlos Casasnovas, Kerstin Becker, Ulla Roggenbuck, Sonali Pechlivanis, Frank J. Kaiser, Matthis Synofzik, Thomas Wirth, Mathieu Anheim, Tobias B. Haack, Paul J. Lockhart, Karl-Heinz Jöckel, Aurora Pujol, Stephan Klebe, Dagmar Timmann, Christel Depienne
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Repeat expansions in FGF14 cause autosomal dominant late-onset cerebellar ataxia (SCA27B) with estimated pathogenic thresholds of 250 (incomplete penetrance) and 300 AAG repeats (full penetrance), but the sequence of pathogenic and non-patho
Externí odkaz:
https://doaj.org/article/6570a285e9844430857f2e885f205ade
Autor:
Karl-Heinz Linne von Berg, Leonie Keilholz, Nadine Küchenmeister, Ekaterina Pushkareva, Burkhard Becker
Publikováno v:
Phycology, Vol 4, Iss 3, Pp 414-426 (2024)
While molecular methods have begun to transform ecology, most algal biodiversity is still studied using the classical approach of identifying microalgae by light microscopy directly in sample material or using cultures. In this study, we compare both
Externí odkaz:
https://doaj.org/article/b543a33c031d4e0c835493b263d9941f
Autor:
Hauke Thomsen, Subhayan Chattopadhyay, Niels Weinhold, Pavel Vodicka, Ludmila Vodickova, Per Hoffmann, Markus M. Nöthen, Karl-Heinz Jöckel, Börge Schmidt, Roman Hajek, Göran Hallmans, Ulrika Pettersson-Kymmer, Florentin Späth, Hartmut Goldschmidt, Kari Hemminki, Asta Försti
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Genome-wide association studies (GWASs) based on common single nucleotide polymorphisms (SNPs) have identified several loci associated with the risk of monoclonal gammopathy of unknown significance (MGUS), a precursor condition for multiple
Externí odkaz:
https://doaj.org/article/56d5d5cebeba496e871fe8346df21e90
Autor:
Jan Mohring, Neele Leithäuser, Jarosław Wlazło, Marvin Schulte, Maximilian Pilz, Johanna Münch, Karl-Heinz Küfer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Wastewater based epidemiology has become a widely used tool for monitoring trends of concentrations of different pathogens, most notably and widespread of SARS-CoV-2. Therefore, in 2022, also in Rhineland–Palatinate, the Ministry of Scienc
Externí odkaz:
https://doaj.org/article/84d3ea8b9cfe4ffaba9dfa77295041a9
Autor:
Karl-Heinz Nenning, Ting Xu, Arielle Tambini, Alexandre R. Franco, Daniel S. Margulies, Stanley J. Colcombe, Michael P. Milham
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-7 (2024)
Abstract Brain connectome analysis suffers from the high dimensionality of connectivity data, often forcing a reduced representation of the brain at a lower spatial resolution or parcellation. This is particularly true for graph-based representations
Externí odkaz:
https://doaj.org/article/05dee1f385354fef8ff193a03ba49759
Publikováno v:
Digital Health, Vol 10 (2024)
Objective In the past two decades, mindfulness, rooted in Buddhist traditions, has gained considerable scientific interest. Virtual reality (VR) technology, in particular head-mounted displays, offers immersive experiences and is examined in this sys
Externí odkaz:
https://doaj.org/article/9b3a1c41036f4708a87ff610bdb668e1
Autor:
EFSA Panel on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Laurence Castle, Gisela Degen, Karl‐Heinz Engel, Paul Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Rainer Gürtler, Trine Husøy, Melania Manco, Wim Mennes, Peter Moldeus, Sabina Passamonti, Romina Shah, Ine Waalkens‐Berendsen, Matthew Wright, Cristina Andreoli, Maria Bastos, Diane Benford, Margherita Bignami, Claudia Bolognesi, Karlien Cheyns, Emanuela Corsini, Riccardo Crebelli, Birgit Dusemund, Rex Fitzgerald, Eric Gaffet, Katrin Loeschner, Francesca Marcon, Jan Mast, Manuela Mirat, Alicja Mortensen, Agnes Oomen, Josef Schlatter, Dominique Turck, Beate Ulbrich, Anna Undas, Christiane Vleminckx, Detlef Woelfle, Ruud Woutersen, Stefania Barmaz, Borana Dino, Gabriele Gagliardi, Sara Levorato, Elena Mazzoli, Alexis Nathanail, Ana Maria Rincon, Laura Ruggeri, Camilla Smeraldi, Alexandra Tard, Sam Vermeiren, Ursula Gundert‐Remy
Publikováno v:
EFSA Journal, Vol 22, Iss 10, Pp n/a-n/a (2024)
Abstract The present opinion is the follow‐up of the conclusions and recommendations of the Scientific Opinion on the re‐evaluation of silicon dioxide (E 551) as a food additive relevant to the safety assessment for all age groups. In addition, t
Externí odkaz:
https://doaj.org/article/553de7e3e44d42b889ab1048ef895614
Autor:
Marina O. Rontogianni, Dipender Gill, Emmanouil Bouras, Alexandros-Georgios Asimakopoulos, Ioanna Tzoulaki, Ville Karhunen, Terho Lehtimäki, Olli Raitakari, Matthias Wielscher, Veikko Salomaa, Sirpa Jalkanen, Marko Salmi, Markku Timonen, James Yarmolinsky, Jing Chen, Martin D. Tobin, Abril G. Izquierdo, Karl-Heinz Herzig, Anne E. Ioannides, Marjo-Riitta Jarvelin, Abbas Dehghan, Konstantinos K. Tsilidis
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110704- (2024)
Summary: We investigated the effects of 35 inflammatory cytokines on respiratory outcomes, including COVID-19, asthma (atopic and non-atopic), chronic obstructive pulmonary disease (COPD), and pulmonary function indices, using Mendelian randomization
Externí odkaz:
https://doaj.org/article/eeb3d7c82b994b05a0ca4ff542ec24dc
Autor:
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Jacqueline Castenmiller, Stefaan de Henauw, Karl‐heinz Engel, Karen Ildico Hirsch‐Ernst, John Kearney, Helle Katrine Knutsen, Alexandre Maciuk, Inge Mangelsdorf, Harry J. McArdle, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Sophia Tsabouri, Marco Vinceti, Carmen Peláez, Henk vanLoveren, Wolfgang Gelbmann, Ermolaos Ververis, Emanuela Turla
Publikováno v:
EFSA Journal, Vol 22, Iss 9, Pp n/a-n/a (2024)
Abstract The European Commission requested EFSA to update the scientific guidance for the preparation of notifications for authorisation of traditional foods, previously developed following the adoption of Regulation (EU) 2015/2283 on novel foods. Th
Externí odkaz:
https://doaj.org/article/bf302fbfc19c4e2a9560b02cf43d0f8b