Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Karl-Friedrich Beck"'
Publikováno v:
Metabolites, Vol 13, Iss 3, p 426 (2023)
Redox-active mediators are now appreciated as powerful molecules to regulate cellular dynamics such as viability, proliferation, migration, cell contraction, and relaxation, as well as gene expression under physiological and pathophysiological condit
Externí odkaz:
https://doaj.org/article/ee2a5cbcf1644790b4259ce3ce59d343
Autor:
Huijing Xia, Zhen Li, Thomas E. Sharp, David J. Polhemus, Jean Carnal, Karl H. Moles, Ya‐Xiong Tao, John Elrod, Josef Pfeilschifter, Karl‐Friedrich Beck, David J. Lefer
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 19 (2020)
Background Hydrogen sulfide (H2S) is an important endogenous physiological signaling molecule and exerts protective properties in the cardiovascular system. Cystathionine γ‐lyase (CSE), 1 of 3 H2S producing enzyme, is predominantly localized in th
Externí odkaz:
https://doaj.org/article/c13eff3d2bb24ff8b38bcf1072bbc657
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 207 (2022)
Renal glomerular diseases such as glomerulosclerosis and diabetic nephropathy often result in the loss of glomerular function and consequently end-stage renal disease. The glomerulus consists of endothelial cells, mesangial cells and glomerular epith
Externí odkaz:
https://doaj.org/article/dba0d500c7e1472fb8f41ad7db1d134b
Autor:
Zhen Li, Huijing Xia, Thomas E. Sharp, Kyle B. LaPenna, Antonia Katsouda, John W. Elrod, Josef Pfeilschifter, Karl-Friedrich Beck, Shi Xu, Ming Xian, Traci T. Goodchild, Andreas Papapetropoulos, David J. Lefer
Publikováno v:
Circulation Research. 132:154-166
Background: Hydrogen sulfide is a critical endogenous signaling molecule that exerts protective effects in the setting of heart failure. Cystathionine γ-lyase (CSE), 1 of 3 hydrogen-sulfide–producing enzyme, is predominantly localized in the vascu
Publikováno v:
Biomolecules. 12(2)
Renal glomerular diseases such as glomerulosclerosis and diabetic nephropathy often result in the loss of glomerular function and consequently end-stage renal disease. The glomerulus consists of endothelial cells, mesangial cells and glomerular epith
Autor:
Zhen Li, Huijing Xia, Thomas E Sharp, Kyle Lapenna, John W Elrod, Josef Pfeilschifter, Karl-Friedrich Beck, Traci T Goodchild, David J Lefer
Publikováno v:
Circulation. 144
Introduction: Hydrogen sulfide (H 2 S) is a critical endogenous signaling molecule that exerts protective effects in the setting of heart failure (HF). Cystathionine γ-lyase (CSE), one of three H 2 S producing enzyme, is predominantly localized in t
Autor:
Huijing Xia, Zhen Li, Kyle LaPenna, Jake Doiron, Thomas Sharp, Karl Moles, John Elrod, Josef Pfeilschifter, Karl-Friedrich Beck, Traci Goodchild, David Lefer
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:130
Publikováno v:
Cellular signalling. 77
Glomerular injury is a hallmark of kidney diseases such as diabetic nephropathy, IgA nephropathy or other forms of glomerulonephritis. Glomerular endothelial cells, mesangial cells, glomerular epithelial cells (podocytes) and, in an inflammatory cont
Autor:
Josef Pfeilschifter, Tzung-Harn Louise Hsieh, Mohamed Ibrahim Abu Hassan, Martina Beck, Ahmed Aglan, Meike Boosen, Nathalie Dehne, Sebastian Longen, Liliana Schaefer, Yvette Köhler, Claudia Tredup, Karl-Friedrich Beck
Publikováno v:
Journal of Molecular Medicine. 95:257-271
Renal mesangial cells are regarded as main players in glomerular inflammatory diseases. To investigate a possible crosstalk between inflammatory and hypoxia-driven signaling processes, we stimulated cultured mouse mesangial cells with different infla
Publikováno v:
Pharmacological Research. 111:642-651
During the last decades, small inorganic molecules like reactive oxygen species (ROS), nitric oxide (NO), carbon monoxide (CO) and even the highly toxic hydrogen sulfide (H2S) have been evolved as important signaling molecules that trigger crucial ce