Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Karl-Fredrik Norrback"'
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98682 (2014)
BACKGROUND: Depression in unipolar and bipolar disorders is associated with hypothalamic-pituitary-adrenal-axis (HPA-axis) hyperactivity. Also, unipolar disorder has recently been shown to exhibit HPA-axis hypoactivity. We studied for the first time
Externí odkaz:
https://doaj.org/article/4d40e23e589d430c943087a877ce0634
Autor:
Mikael Wikgren, Thomas Karlsson, Johanna Lind, Therese Nilbrink, Johan Hultdin, Kristel Sleegers, Christine Van Broeckhoven, Göran Roos, Lars-Göran Nilsson, Lars Nyberg, Rolf Adolfsson, Karl-Fredrik Norrback
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34292 (2012)
Telomere length shortens with cellular division, and leukocyte telomere length is used as a marker for systemic telomere length. The hippocampus hosts adult neurogenesis and is an important structure for episodic memory, and carriers of the apolipopr
Externí odkaz:
https://doaj.org/article/446e3bf180e2420eb69f8ef9d36c72c6
Autor:
Pontus Karling, Åke Danielsson, Mikael Wikgren, Ingegerd Söderström, Jurgen Del-Favero, Rolf Adolfsson, Karl-Fredrik Norrback
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18035 (2011)
BackgroundThe catechol-O-methyltransferase (COMT) enzyme has a key function in the degradation of catecholamines and a functional polymorphism is val158met. The val/val genotype results in a three to fourfold higher enzymatic activity compared with t
Externí odkaz:
https://doaj.org/article/d99ed50d3faf4050a956452da06a68fb
Autor:
Lotte N Moens, Peter De Rijk, Joke Reumers, Maarten J A Van den Bossche, Wim Glassee, Sonia De Zutter, An-Sofie Lenaerts, Annelie Nordin, Lars-Göran Nilsson, Ignacio Medina Castello, Karl-Fredrik Norrback, Dirk Goossens, Kristel Van Steen, Rolf Adolfsson, Jurgen Del-Favero
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23450 (2011)
In recent years, DISC1 has emerged as one of the most credible and best supported candidate genes for schizophrenia and related neuropsychiatric disorders. Furthermore, increasing evidence--both genetic and functional--indicates that many of its prot
Externí odkaz:
https://doaj.org/article/51dbf406fe0144f3a7e828aba9908cb4
Autor:
Katarina Nordfjäll, Ulrika Svenson, Karl-Fredrik Norrback, Rolf Adolfsson, Per Lenner, Göran Roos
Publikováno v:
PLoS Genetics, Vol 5, Iss 2, p e1000375 (2009)
Age-associated telomere shortening is a well documented feature of peripheral blood cells in human population studies, but it is not known to what extent these data can be transferred to the individual level. Telomere length (TL) in two blood samples
Externí odkaz:
https://doaj.org/article/f016543d74054b989cc75fa1e3281cbf
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 23; Pages: 7158
Bipolar disorder is associated with a long range of medical comorbidities, including migraine, diabetes, and cardiovascular disease. Bipolar disorder has also been associated with an increased risk of bone fractures. Osteoporosis is a reduction in bo
Publikováno v:
Neurology, Psychiatry and Brain Research. 34:34-40
Background: Although bipolar disorder (BP) is associated with impaired quality of life (QOL), little is known about the clinical features associated with QOL. Better knowledge about this relationsh ...
Publikováno v:
Journal of Affective Disorders. 213:161-167
A hyperactive hypothalamic-pituitary-adrenal axis (HPA-axis) is a well-known phenomenon in bipolar disorder (BD). However, hypocortisolism has also been described and found associated with depression, low quality of life and cardiovascular risk facto
Publikováno v:
World Journal of Gastroenterology
AIM: To study if anxiety, depression and experience of stress are associated with gastrointestinal (GI) symptoms in patients with bipolar disorder. METHODS: A total of 136 patients with bipolar disorder (mean age 49.9 years; 61% women) and 136 contro
Publikováno v:
Journal of Neurogastroenterology and Motility
Background/Aims Gastrointestinal symptoms and hypothalamus-pituitary-adrenal (HPA) axis dysfunction are frequently observed in patients with major depression. The primary aim of the study was to investigate the relationship between HPA-axis function