Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Karl-Fr. Sewing"'
Autor:
Siegfried Wagner, Winfried Beil, P A Bertram-Drogatz, Karl-Fr. Sewing, I Sobek-Klocke, D. Wingbermühle, Michael P. Manns, C Möller
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases. 18:490-495
Helicobacter pylori shows a rather high variability of several biochemical markers including lipopolysaccharide structures. This study aimed to determine whether Helicobacter pylori has a potential for phenotypic variability and to describe its effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f5b4d8fa60a66c95820444e1073cc6
https://doi.org/10.1007/s100960050329
https://doi.org/10.1007/s100960050329
Publikováno v:
Pharmacology. 50:333-337
The effects of various types of antiulcer agents against Helicobacter pylori F1-ATPase were studied. ATPase was released into the aqueous phase (i.e., solubilized) by son
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2fcc44bfc9e3fad2d4da76ea7c350d1
https://doi.org/10.1159/000139299
https://doi.org/10.1159/000139299
Publikováno v:
Pharmacology. 48:176-186
Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are the major phospholipids of the gastric mucosal surface barrier and chiefly originate from mucous cells. Among these phospholipids PC with palmitic acid as its hydrophobic moieties is beli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1093030786b6babffd1ab6be83653c05
https://doi.org/10.1159/000139177
https://doi.org/10.1159/000139177
Autor:
R. Kownatzki, Heinfried H. Radeke, Uwe Christians, Hans-Martin Schiebel, Schottmann R, Karl-Fr. Sewing
Publikováno v:
Clinical Biochemistry. 24:271-275
Metabolism of FK506, a 23 member macrolide under clinical investigation as immunosuppressant after transplantation, was studied using human liver microsomes. Two fractions isolated by semipreparative HPLC were identified by negative fast atom bombard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851c606c1cdc7f0883a8557acd5e54ea
https://doi.org/10.1016/0009-9120(91)80019-y
https://doi.org/10.1016/0009-9120(91)80019-y
Publikováno v:
Biochemical Pharmacology. 40:1997-2003
The effects of the anti-inflammatory seleno-organic compound ebselen on gastric H+/K(+)-ATPase, H+/K(+)-ATPase-mediated proton transport and on parietal cell HCl production was studied. Ebselen inhibited K(+)-stimulated ATPase activity in leaky gastr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d836aa18c35707a56671d45d8e2b9f0
https://doi.org/10.1016/0006-2952(90)90229-e
https://doi.org/10.1016/0006-2952(90)90229-e
Publikováno v:
Pharmacology. 40:8-20
The calcium channel antagonists verapamil, gallopamil and nifedipine were tested for their effects on acid secretion stimulated by histamine and dibutyryl-cyclic AMP in isolated and enriched guinea pi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ec6db1bfeb025add8d28eb13976018a
https://doi.org/10.1159/000138633
https://doi.org/10.1159/000138633
Autor:
Michael P. Manns, Natalie J. Serkova, Gabriele I. Kirchner, Leslie Z. Benet, Uwe Christians, Wolfgang Jacobsen, Christian Vidal, Karl-Fr. Sewing
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 748(1)
We developed a universal LC-mass spectrometry assay with automated online extraction (LC/LC-MS) to quantify the immunosuppressants cyclosporine, tacrolimus, sirolimus and SDZ-RAD alone or in combination in whole blood. After protein precipitation, sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f1324da930a9e2683f3b3e6f3def8f
https://pubmed.ncbi.nlm.nih.gov/11092585
https://pubmed.ncbi.nlm.nih.gov/11092585
Publikováno v:
European journal of pharmacology. 218(2-3)
The action of the H+/K(+)-ATPase inhibitors pantoprazole and omeprazole was compared in different in vitro test systems. In gastric membrane vesicles under conditions shown to result in acidification of the vesicle interior, pantoprazole and omeprazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd64e98bfbcee26680bd04e8c449a8a6
https://pubmed.ncbi.nlm.nih.gov/1330598
https://pubmed.ncbi.nlm.nih.gov/1330598
Autor:
Karl-Fr. Sewing, H. J. Ruoff
Publikováno v:
European Journal of Pharmacology. 32:227-232
In normal rats the effect of atropine and metiamide was studied on cAMP levels of resting and histamine-, pentagastrin-, carbachol- and insulin-stimulated gastric mucosa. In vagotomized rats gastric mucosal cAMP levels were investigated under basal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5aac7814efeef66a867b4893ca89315
https://doi.org/10.1016/0014-2999(75)90287-3
https://doi.org/10.1016/0014-2999(75)90287-3
Publikováno v:
Biochemical Pharmacology. 37:843-848
The inhibitory effects of omeprazole and omeprazole-derived metabolites were studied on Escherichia coli glutaminase activity at pH 2.5 which might represent the conditions present at the target enzyme (K + /H + -ATPase) in the secretory membrane of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfded97de329ce65f036c485bea5b120
https://doi.org/10.1016/0006-2952(88)90170-0
https://doi.org/10.1016/0006-2952(88)90170-0