Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Karl-Ferdinand Lechtreck"'
Publikováno v:
Cells, Vol 7, Iss 7, p 79 (2018)
During ciliogenesis, centrioles convert to membrane-docked basal bodies, which initiate the formation of cilia/flagella and template the nine doublet microtubules of the flagellar axoneme. The discovery that many human diseases and developmental diso
Externí odkaz:
https://doaj.org/article/85a268b2155e44b3b4d8a19217279fac
Publikováno v:
Wingfield, J L, Lechtreck, K-F & Lorentzen, E 2018, ' Trafficking of ciliary membrane proteins by the intraflagellar transport/BBSome machinery ', Essays in Biochemistry, vol. 62, no. 6, pp. 753-763 . https://doi.org/10.1042/EBC20180030
Bardet–Biedl syndrome (BBS) is a rare inherited disease caused by defects in the BBSome, an octameric complex of BBS proteins. The BBSome is conserved in most organisms with cilia, which are microtubule (MT)-based cell organelles that protrude from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551b727d31928ba4b11cff312f3b08ce
https://pure.au.dk/portal/da/publications/trafficking-of-ciliary-membrane-proteins-by-the-intraflagellar-transportbbsome-machinery(a1468b85-cbb6-439c-a193-76c68c887e41).html
https://pure.au.dk/portal/da/publications/trafficking-of-ciliary-membrane-proteins-by-the-intraflagellar-transportbbsome-machinery(a1468b85-cbb6-439c-a193-76c68c887e41).html
Getting tubulin to the tip of the cilium: One IFT train, many different tubulin cargo-binding sites?
Autor:
Benjamin D. Engel, Karl-Ferdinand Lechtreck, Kristina Weber, Sagar Bhogaraju, Esben Lorentzen
Publikováno v:
BioEssays. 36:463-467
Cilia are microtubule-based hair-like structures that project from the surfaces of eukaryotic cells. Cilium formation relies on intraflagellar transport (IFT) to move ciliary proteins such as tubulin from the site of synthesis in the cell body to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dabda5c4c4d40aaf06e2d15880e612f3
https://doi.org/10.1002/bies.201400007
https://doi.org/10.1002/bies.201400007
Autor:
James E. Evans, Karl-Ferdinand Lechtreck, George B. Witman, Jason M. Brown, Julie M. Craft, Julio L. Sampaio, Andrej Shevchenko
Publikováno v:
The Journal of Cell Biology
The BBSome, a regulator of ciliary membrane protein composition, is required only for the export phase of a process that continuously cycles phospholipase D through cilia.
The BBSome is a complex of seven proteins, including BBS4, that is cycled
The BBSome is a complex of seven proteins, including BBS4, that is cycled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868091998e4f15c2458bf123fe72c098
https://doi.org/10.1083/jcb.201207139
https://doi.org/10.1083/jcb.201207139
Autor:
Wallace F. Marshall, Kimberly A. Wemmer, Karl-Ferdinand Lechtreck, George B. Witman, William B. Ludington
Publikováno v:
Proceedings of the National Academy of Sciences. 110:3925-3930
Cilia and flagella are microtubule-based organelles that protrude from the cell body. Ciliary assembly requires intraflagellar transport (IFT), a motile system that delivers cargo from the cell body to the flagellar tip for assembly. The process cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9f368993308d0db001995d6fc72080
https://doi.org/10.1073/pnas.1217354110
https://doi.org/10.1073/pnas.1217354110
Autor:
Yuqing Hou, Branch Craige, Dennis R. Diener, Che-Chia Tsao, Joel L. Rosenbaum, Karl-Ferdinand Lechtreck, George B. Witman
Publikováno v:
The Journal of Cell Biology
Entry and exit of proteins into flagella is gauged by CEP290 in the transition zone.
Mutations in human CEP290 cause cilia-related disorders that range in severity from isolated blindness to perinatal lethality. Here, we describe a Chlamydomonas
Mutations in human CEP290 cause cilia-related disorders that range in severity from isolated blindness to perinatal lethality. Here, we describe a Chlamydomonas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5dd9153867decebaf39b4b5133571c4
http://europepmc.org/articles/PMC2935561
http://europepmc.org/articles/PMC2935561
Proteins related to green algal striated fiber assemblin are present in stramenopiles and alveolates
Publikováno v:
Protoplasma. 236:97-101
In green algae, striated fiber assemblin (SFA) is the major protein of the striated microtubule-associated fibers that are structural elements in the flagellar basal apparatus. Using Basic Local Alignment Search Tool (BLAST) searches of recently esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ef7146e3859da780d4d4e8fae66de6
https://doi.org/10.1007/s00709-009-0041-z
https://doi.org/10.1007/s00709-009-0041-z
Autor:
Philippe Delmotte, Michael J. Sanderson, Michael L. Robinson, George B. Witman, Karl-Ferdinand Lechtreck
Publikováno v:
The Journal of Cell Biology
Chlamydomonas reinhardtii hydin is a central pair protein required for flagellar motility, and mice with Hydin defects develop lethal hydrocephalus. To determine if defects in Hydin cause hydrocephalus through a mechanism involving cilia, we compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe4d7330c3176ad083f7f02fedced4c
https://doi.org/10.1083/jcb.200710162
https://doi.org/10.1083/jcb.200710162
Publikováno v:
Eukaryotic Cell. 4:1959-1962
An inverted repeat corresponding to parts of the centrin gene of Chlamydomonas reinhardtii was placed downstream of the NIT1 promoter, which is induced by ammonium starvation. After induction, transformants developed centrin deficiency as assayed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1c09cc9ba8dd8b337d986f697ee42f
https://doi.org/10.1128/ec.4.11.1959-1962.2005
https://doi.org/10.1128/ec.4.11.1959-1962.2005
Autor:
Karl-Ferdinand Lechtreck
Publikováno v:
Phycologia. 43:635-640
The posttranslational modifications of tubulin of Chrysochromulina parva were determined using specific antibodies. Haptonematal microtubules were acetylated, monoglutamylated and weakly detyrosinated, a pattern distinct from that of the flagella of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff4091aab7ee6dce0faad585f25235da
https://doi.org/10.2216/i0031-8884-43-5-635.1
https://doi.org/10.2216/i0031-8884-43-5-635.1