Inhibition of Aspergillus fumigatus and Its Biofilm by Pseudomonas aeruginosa Is Dependent on the Source, Phenotype and Growth Conditions of the Bacterium.

Autor: Jose A G Ferreira, John C Penner, Richard B Moss, Janus A J Haagensen, Karl V Clemons, Alfred M Spormann, Hasan Nazik, Kevin Cohen, Niaz Banaei, Elisabete Carolino, David A Stevens

Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0134692 (2015)

Aspergillus fumigatus (Af) and Pseudomonas aeruginosa (Pa) are leading fungal and bacterial pathogens, respectively, in many clinical situations. Relevant to this, their interface and co-existence has been studied. In some experiments in vitro, Pa pr

Externí odkaz: https://doaj.org/article/44eb996e2ba248d3b757e8258bc01c41

Influence of 17β-estradiol on gene expression of Paracoccidioides during mycelia-to-yeast transition.

Autor: Jata Shankar, Thomas D Wu, Karl V Clemons, Jomar P Monteiro, Laurence F Mirels, David A Stevens

Publikováno v: PLoS ONE, Vol 6, Iss 12, p e28402 (2011)

BackgroundParacoccidioides is the causative agent of paracoccidioidomycosis, a systemic mycosis endemic to Latin America. Infection is initiated by inhalation of conidia (C) or mycelial (M) fragments, which subsequently differentiate into yeast (Y).

Externí odkaz: https://doaj.org/article/f4cadcd418c949a6a8431b4cb4aaf7e9

Protective role of CFTR during fungal infection of cystic fibrosis bronchial epithelial cells with Aspergillus fumigatus

Autor: Beate Illek, Horst Fischer, Terry E. Machen, Gopika Hari, Karl V. Clemons, Gabriele Sass, Jose A. G. Ferreira, David A. Stevens

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)

Lung infection with the fungus Aspergillus fumigatus (Af) is a common complication in cystic fibrosis (CF) and is associated with loss of pulmonary function. We established a fungal epithelial co-culture model to examine the impact of Af infection on

Externí odkaz: https://doaj.org/article/1eff90caf00c4a57978ba97a208d2278

The role of occupational Aspergillus exposure in the development of diseases

Autor: Cristina Veríssimo, David A. Stevens, Karl V. Clemons, Malcolm Richardson, Raquel Sabino, João Brandão, Carla Viegas, Magna Alves-Correia, Susana Viegas, Luís Miguel Borrego

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Sabino, R, Verissímo, C, Viegas, C, Viegas, S, Brandão, J, Alves-Correia, M, Borrego, L-M, Clemons, K V, Stevens, D A & Richardson, M 2019, ' The role of occupational Aspergillus exposure in the development of diseases ', Medical Mycology, vol. 57, no. 2, pp. s196-s205 . https://doi.org/10.1093/mmy/myy090

C The Author(s) 2019. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com
Aspergillus spp. have a high nutri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559a73ebf149cb6c5840d856983339bc
https://doi.org/10.1093/mmy/myy090

Efficacy and Associated Drug Exposures of Isavuconazole and Fluconazole in an Experimental Model of Coccidioidomycosis

Autor: Karl V. Clemons, Gabriele Sass, Hasan Nazik, Therese M Kitt, William W. Hope, David A. Stevens, Marife Martinez, Nathan P. Wiederhold, Laura L. Kovanda

Publikováno v: Antimicrobial Agents and Chemotherapy

Coccidioides spp. are important pathogens in regions where they are endemic, and new treatment options are needed. Here, isavuconazonium sulfate (ISAVUSULF) and fluconazole (FLU) were evaluated in experimental disseminated coccidioidomycosis to chara

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b3074956477db627ddc3ed0d1a8248
https://doi.org/10.1128/aac.02344-20