Zobrazeno 1 - 10
of 616
pro vyhledávání: '"Karl T Kelsey"'
Autor:
DeVon Hunter-Schlichting, Karl T Kelsey, Ryan Demmer, Manish Patel, Raphael Bueno, Brock Christensen, Naomi Fujioka, Deepa Kolarseri, Heather H Nelson
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0254136 (2021)
Human cytomegalovirus (HCMV) is a highly prevalent herpes virus which persists as a latent infection and has been detected in several different tumor types. HCMV disease is rare but may occur in high-risk settings, often manifesting as a pulmonary in
Externí odkaz:
https://doaj.org/article/fb13723d960d4c7a8854dba020916b2b
Autor:
Caihua Liang, Karl T Kelsey, Michael D McClean, Brock C Christensen, Carmen J Marsit, Margaret R Karagas, Tim Waterboer, Michael Pawlita, Heather H Nelson
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123716 (2015)
HPV infection is a causal agent in many epithelial cancers, yet our understanding of genetic susceptibility to HPV infection and resultant cancer risk is limited. Epidermodysplasia Verruciformis is a rare condition of extreme susceptibility to cutane
Externí odkaz:
https://doaj.org/article/e5c99feef8f8490f98d1c04a70c2dff7
Autor:
Angeline S Andrew, Ting Hu, Jian Gu, Jiang Gui, Yuanqing Ye, Carmen J Marsit, Karl T Kelsey, Alan R Schned, Sam A Tanyos, Eben M Pendleton, Rebecca A Mason, Elaine V Morlock, Michael S Zens, Zhongze Li, Jason H Moore, Xifeng Wu, Margaret R Karagas
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51301 (2012)
Bladder cancer is the 4(th) most common cancer among men in the U.S. We analyzed variant genotypes hypothesized to modify major biological processes involved in bladder carcinogenesis, including hormone regulation, apoptosis, DNA repair, immune surve
Externí odkaz:
https://doaj.org/article/2bd3b44368954f89932e96d6094d03e7
Autor:
James D McKay, Therese Truong, Valerie Gaborieau, Amelie Chabrier, Shu-Chun Chuang, Graham Byrnes, David Zaridze, Oxana Shangina, Neonila Szeszenia-Dabrowska, Jolanta Lissowska, Peter Rudnai, Eleonora Fabianova, Alexandru Bucur, Vladimir Bencko, Ivana Holcatova, Vladimir Janout, Lenka Foretova, Pagona Lagiou, Dimitrios Trichopoulos, Simone Benhamou, Christine Bouchardy, Wolfgang Ahrens, Franco Merletti, Lorenzo Richiardi, Renato Talamini, Luigi Barzan, Kristina Kjaerheim, Gary J Macfarlane, Tatiana V Macfarlane, Lorenzo Simonato, Cristina Canova, Antonio Agudo, Xavier Castellsagué, Ray Lowry, David I Conway, Patricia A McKinney, Claire M Healy, Mary E Toner, Ariana Znaor, Maria Paula Curado, Sergio Koifman, Ana Menezes, Victor Wünsch-Filho, José Eluf Neto, Leticia Fernández Garrote, Stefania Boccia, Gabriella Cadoni, Dario Arzani, Andrew F Olshan, Mark C Weissler, William K Funkhouser, Jingchun Luo, Jan Lubiński, Joanna Trubicka, Marcin Lener, Dorota Oszutowska, Stephen M Schwartz, Chu Chen, Sherianne Fish, David R Doody, Joshua E Muscat, Philip Lazarus, Carla J Gallagher, Shen-Chih Chang, Zuo-Feng Zhang, Qingyi Wei, Erich M Sturgis, Li-E Wang, Silvia Franceschi, Rolando Herrero, Karl T Kelsey, Michael D McClean, Carmen J Marsit, Heather H Nelson, Marjorie Romkes, Shama Buch, Tomoko Nukui, Shilong Zhong, Martin Lacko, Johannes J Manni, Wilbert H M Peters, Rayjean J Hung, John McLaughlin, Lars Vatten, Inger Njølstad, Gary E Goodman, John K Field, Triantafillos Liloglou, Paolo Vineis, Francoise Clavel-Chapelon, Domenico Palli, Rosario Tumino, Vittorio Krogh, Salvatore Panico, Carlos A González, J Ramón Quirós, Carmen Martínez, Carmen Navarro, Eva Ardanaz, Nerea Larrañaga, Kay-Tee Khaw, Timothy Key, H Bas Bueno-de-Mesquita, Petra H M Peeters, Antonia Trichopoulou, Jakob Linseisen, Heiner Boeing, Göran Hallmans, Kim Overvad, Anne Tjønneland, Merethe Kumle, Elio Riboli, Kristjan Välk, Tõnu Vooder, Andres Metspalu, Diana Zelenika, Anne Boland, Marc Delepine, Mario Foglio, Doris Lechner, Hélène Blanché, Ivo G Gut, Pilar Galan, Simon Heath, Mia Hashibe, Richard B Hayes, Paolo Boffetta, Mark Lathrop, Paul Brennan
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1001333 (2011)
Genome-wide association studies (GWAS) have been successful in identifying common genetic variation involved in susceptibility to etiologically complex disease. We conducted a GWAS to identify common genetic variation involved in susceptibility to up
Externí odkaz:
https://doaj.org/article/846c8a4060ef41a19a022b13df570b81
Autor:
Sara E Pacheco, E Andres Houseman, Brock C Christensen, Carmen J Marsit, Karl T Kelsey, Mark Sigman, Kim Boekelheide
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20280 (2011)
In previous studies using candidate gene approaches, low sperm count (oligospermia) has been associated with altered sperm mRNA content and DNA methylation in both imprinted and non-imprinted genes. We performed a genome-wide analysis of sperm DNA me
Externí odkaz:
https://doaj.org/article/c965e9bdd36d4f0cb912438f19e15d83
Autor:
Carmen J Marsit, E Andres Houseman, Brock C Christensen, Luc Gagne, Margaret R Wrensch, Heather H Nelson, Joseph Wiemels, Shichun Zheng, John K Wiencke, Angeline S Andrew, Alan R Schned, Margaret R Karagas, Karl T Kelsey
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12334 (2010)
Approximately 500,000 individuals diagnosed with bladder cancer in the U.S. require routine cystoscopic follow-up to monitor for disease recurrences or progression, resulting in over $2 billion in annual expenditures. Identification of new diagnostic
Externí odkaz:
https://doaj.org/article/0bcd9da35e00445ea0be884fabe4e1ce
Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake.
Autor:
Brock C Christensen, Karl T Kelsey, Shichun Zheng, E Andres Houseman, Carmen J Marsit, Margaret R Wrensch, Joseph L Wiemels, Heather H Nelson, Margaret R Karagas, Lawrence H Kushi, Marilyn L Kwan, John K Wiencke
Publikováno v:
PLoS Genetics, Vol 6, Iss 7, p e1001043 (2010)
Although tumor size and lymph node involvement are the current cornerstones of breast cancer prognosis, they have not been extensively explored in relation to tumor methylation attributes in conjunction with other tumor and patient dietary and hormon
Externí odkaz:
https://doaj.org/article/607d3de014c64f26b8fcbb09682fcba1
Autor:
Graham M Poage, Brock C Christensen, E Andres Houseman, Michael D McClean, John K Wiencke, Marshall R Posner, John R Clark, Heather H Nelson, Carmen J Marsit, Karl T Kelsey
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9651 (2010)
Solid tumors, including head and neck squamous cell carcinomas (HNSCC), arise as a result of genetic and epigenetic alterations in a sustained stress environment. Little work has been done that simultaneously examines the spectrum of both types of ch
Externí odkaz:
https://doaj.org/article/6839a90965f34dabac2d68bc79f9044b
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9372 (2010)
Autism is associated with high rates of genomic aberrations, including chromosomal rearrangements and de novo copy-number variations. These observations are reminiscent of cancer, a disease where genomic rearrangements also play a role. We undertook
Externí odkaz:
https://doaj.org/article/e4fbad0369eb414faafdf600f280e3ad
Autor:
Brock C Christensen, E Andres Houseman, Carmen J Marsit, Shichun Zheng, Margaret R Wrensch, Joseph L Wiemels, Heather H Nelson, Margaret R Karagas, James F Padbury, Raphael Bueno, David J Sugarbaker, Ru-Fang Yeh, John K Wiencke, Karl T Kelsey
Publikováno v:
PLoS Genetics, Vol 5, Iss 8, p e1000602 (2009)
Epigenetic control of gene transcription is critical for normal human development and cellular differentiation. While alterations of epigenetic marks such as DNA methylation have been linked to cancers and many other human diseases, interindividual e
Externí odkaz:
https://doaj.org/article/362e84d0a8124ca8960dba2b31171f73