Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Karl T Butterworth"'
Publikováno v:
F1000Research, Vol 12 (2023)
Background: Preclinical models of radiotherapy (RT) response are vital for the continued success and evolution of RT in the treatment of cancer. The irradiation of tissues in mouse models necessitates high levels of precision and accuracy to recapitu
Externí odkaz:
https://doaj.org/article/ac648bc3ae1f4b7d8bb5639824430be6
Autor:
Stephen J McMahon, Karl T Butterworth, Colman Trainor, Conor K McGarry, Joe M O'Sullivan, Giuseppe Schettino, Alan R Hounsell, Kevin M Prise
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54526 (2013)
It is now widely accepted that intercellular communication can cause significant variations in cellular responses to genotoxic stress. The radiation-induced bystander effect is a prime example of this effect, where cells shielded from radiation expos
Externí odkaz:
https://doaj.org/article/894d4da32ca644499b419274edd390fc
Autor:
Colman Trainor, Karl T Butterworth, Conor K McGarry, Stephen J McMahon, Joe M O'Sullivan, Alan R Hounsell, Kevin M Prise
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43326 (2012)
During the delivery of advanced radiotherapy treatment techniques modulated beams are utilised to increase dose conformity across the target volume. Recent investigations have highlighted differential cellular responses to modulated radiation fields
Externí odkaz:
https://doaj.org/article/f8628e1bfc534ec8b4ece88b6a6c19cf
Autor:
Gerard M. Walls, Valentina Giacometti, Aditya Apte, Maria Thor, Conor McCann, Gerard G. Hanna, John O'Connor, Joseph O. Deasy, Alan R. Hounsell, Karl T. Butterworth, Aidan J. Cole, Suneil Jain, Conor K. McGarry
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 23, Iss , Pp 118-126 (2022)
Background: Emerging data suggest that dose-sparing several key cardiac regions is prognostically beneficial in lung cancer radiotherapy. The cardiac substructures are challenging to contour due to their complex geometry, poor soft tissue definition
Externí odkaz:
https://doaj.org/article/4cb96ab78c3c42538d979ff36e9a946e
Autor:
Kathryn H. Brown, Mihaela Ghita, Ludwig J. Dubois, Dirk de Ruysscher, Kevin M. Prise, Frank Verhaegen, Karl T. Butterworth
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 34, Iss , Pp 112-119 (2022)
Background and purpose: To provide a scoping review of published studies using small animal irradiators and highlight the progress in preclinical radiotherapy (RT) studies enabled by these platforms since their development and commercialization in 20
Externí odkaz:
https://doaj.org/article/9b553f704e0a43eca840dbfeabb33a5b
Autor:
Emily Russell, Victoria Dunne, Ben Russell, Hibaaq Mohamud, Mihaela Ghita, Stephen J. McMahon, Karl T. Butterworth, Giuseppe Schettino, Conor K. McGarry, Kevin M. Prise
Publikováno v:
Radiation Oncology, Vol 16, Iss 1, Pp 1-16 (2021)
Abstract Purpose The recent implementation of MR-Linacs has highlighted theranostic opportunities of contrast agents in both imaging and radiotherapy. There is a lack of data exploring the potential of superparamagnetic iron oxide nanoparticles (SPIO
Externí odkaz:
https://doaj.org/article/395ba23d1e574bf1bc3495e2cccd624d
Autor:
Francesca Amoroso, Kimberley Glass, Reema Singh, Francisco Liberal, Rebecca E. Steele, Sarah Maguire, Rohinton Tarapore, Joshua E. Allen, Sandra Van Schaeybroeck, Karl T. Butterworth, Kevin Prise, Joe M. O’Sullivan, Suneil Jain, David J. Waugh, Ian G. Mills
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Prostate cancer (PCa) is the most common non-cutaneous cancer in men and a notable cause of cancer mortality when it metastasises. The unfolded protein response (UPR) can be cytoprotective but when acutely activated can lead to cell death. I
Externí odkaz:
https://doaj.org/article/e08cdcf6c9974257a805988e30144259
Autor:
Gabriel Adrian, Elise Konradsson, Sarah Beyer, Anders Wittrup, Karl T. Butterworth, Stephen J. McMahon, Mihaela Ghita, Kristoffer Petersson, Crister Ceberg
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundIrradiation with ultra-high dose rate (FLASH) has been shown to spare normal tissue without hampering tumor control in several in vivo studies. Few cell lines have been investigated in vitro, and previous results are inconsistent. Assuming
Externí odkaz:
https://doaj.org/article/469e2113cafa4b189229e664a90ccba4
Autor:
Hisanori Fukunaga, Kiichi Kaminaga, Takuya Sato, Karl T. Butterworth, Ritsuko Watanabe, Noriko Usami, Takehiko Ogawa, Akinari Yokoya, Kevin M. Prise
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Microbeam radiotherapy (MRT) is based on a spatial fractionation of synchrotron X-ray microbeams at the microscale level. Although the tissue-sparing effect (TSE) in response to non-uniform radiation fields was recognized more than one centu
Externí odkaz:
https://doaj.org/article/4359fc8125a84c17ae1d481fc0cd10d4
Autor:
Gerard M Walls, Conor McCann, Peter Ball, Katelyn M Atkins, Raymond H Mak, Ahmed Bedair, Jolyne O'Hare, Jonathan McAleese, Claire Harrison, Karen A Tumelty, Cathryn Crockett, Sarah-Louise Black, Catherine Nelson, John O'Connor, Alan R Hounsell, Conor K McGarry, Karl T Butterworth, Aidan J Cole, Suneil Jain, Gerard G Hanna
Publikováno v:
Walls, G M, McCann, C, Ball, P, Atkins, K M, Mak, R H, Bedair, A, O'Hare, J, McAleese, J, Harrison, C, Tumelty, K A, Crockett, C, Black, S-L, Nelson, C, O'Connor, J, Hounsell, A R, McGarry, C K, Butterworth, K T, Cole, A J, Jain, S & Hanna, G G 2023, ' A pulmonary vein atlas for radiotherapy planning ', Radiotherapy and Oncology, vol. 184, 109680 . https://doi.org/10.1016/j.radonc.2023.109680
Background and PurposeCardiac arrhythmia is a recognised potential complication of thoracic radiotherapy, but the responsible cardiac substructures for arrhythmogenesis have not been identified. Arrhythmogenic tissue is commonly located in the pulmon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e611912b78afe3389244dbd05479c1
https://pure.qub.ac.uk/en/publications/bac88175-6c5a-4b6e-9b20-2b9715659575
https://pure.qub.ac.uk/en/publications/bac88175-6c5a-4b6e-9b20-2b9715659575
