Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Karl Roland Ehrenberg"'
Autor:
Claudia R Ball, Felix Oppel, Karl Roland Ehrenberg, Taronish D Dubash, Sebastian M Dieter, Christopher M Hoffmann, Ulrich Abel, Friederike Herbst, Moritz Koch, Jens Werner, Frank Bergmann, Naveed Ishaque, Manfred Schmidt, Christof von Kalle, Claudia Scholl, Stefan Fröhling, Benedikt Brors, Wilko Weichert, Jürgen Weitz, Hanno Glimm
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 7, Pp 918-932 (2017)
Abstract Although tumor‐initiating cell (TIC) self‐renewal has been postulated to be essential in progression and metastasis formation of human pancreatic adenocarcinoma (PDAC), clonal dynamics of TICs within PDAC tumors are yet unknown. Here, we
Externí odkaz:
https://doaj.org/article/806e5c3796d448e3a3f8956eba08fa15
Autor:
Karl Roland Ehrenberg, Jianpeng Gao, Felix Oppel, Stephanie Frank, Na Kang, Tim Kindinger, Sebastian M. Dieter, Friederike Herbst, Lino Möhrmann, Taronish D. Dubash, Erik R. Schulz, Hendrik Strakerjahn, Klara M. Giessler, Sarah Weber, Ava Oberlack, Eva-Maria Rief, Oliver Strobel, Frank Bergmann, Felix Lasitschka, Jürgen Weitz, Hanno Glimm, Claudia R. Ball
Publikováno v:
Cells, Vol 8, Iss 2, p 142 (2019)
In highly aggressive malignancies like pancreatic cancer (PC), patient-derived tumor models can serve as disease-relevant models to understand disease-related biology as well as to guide clinical decision-making. In this study, we describe a two-step
Externí odkaz:
https://doaj.org/article/1256f87644bb43a386fa5d4e662c089e
Autor:
Hanno Glimm, Stefan Fröhling, Benedikt Brors, Albrecht Stenzinger, Claudia R. Ball, Claudia Scholl, Wilko Weichert, Christof von Kalle, Evelin Schröck, Frank Bergmann, Lars Feuerbach, Christoph Springfeld, Thilo Hackert, Oliver Strobel, Nathalia A. Giese, Marius Horger, Nisar P. Malek, Michael Bitzer, Sebastian Fetscher, Helmut Lambertz, Lothar Schulz, Ranadip Mandal, Matthias Schlesner, Umut H. Toprak, Kortine Kleinheinz, Stephanie Frank, Karl Roland Ehrenberg, Volker Endris, Roland Penzel, Katja Steiger, Daniela Richter, David Bonekamp, Martina Fröhlich, Barbara Hutter, Barbara Klink, Paula L. Codo, Sebastian Uhrig, Peter Horak, Christoph Heining
Supplementary patient data provides a summary on the clinical course of patient 16.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1388a1a26aacb8261996ae38cf3c430a
https://doi.org/10.1158/2159-8290.22532405
https://doi.org/10.1158/2159-8290.22532405
Autor:
Hanno Glimm, Stefan Fröhling, Benedikt Brors, Albrecht Stenzinger, Claudia R. Ball, Claudia Scholl, Wilko Weichert, Christof von Kalle, Evelin Schröck, Frank Bergmann, Lars Feuerbach, Christoph Springfeld, Thilo Hackert, Oliver Strobel, Nathalia A. Giese, Marius Horger, Nisar P. Malek, Michael Bitzer, Sebastian Fetscher, Helmut Lambertz, Lothar Schulz, Ranadip Mandal, Matthias Schlesner, Umut H. Toprak, Kortine Kleinheinz, Stephanie Frank, Karl Roland Ehrenberg, Volker Endris, Roland Penzel, Katja Steiger, Daniela Richter, David Bonekamp, Martina Fröhlich, Barbara Hutter, Barbara Klink, Paula L. Codo, Sebastian Uhrig, Peter Horak, Christoph Heining
Supplementary Figure S1 shows circos plots including 17 PDACs of the patient cohort and a PDCM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015ca4fb9387c18117a24e4d897c6aa4
https://doi.org/10.1158/2159-8290.22532414.v1
https://doi.org/10.1158/2159-8290.22532414.v1
Autor:
Hanno Glimm, Stefan Fröhling, Benedikt Brors, Albrecht Stenzinger, Claudia R. Ball, Claudia Scholl, Wilko Weichert, Christof von Kalle, Evelin Schröck, Frank Bergmann, Lars Feuerbach, Christoph Springfeld, Thilo Hackert, Oliver Strobel, Nathalia A. Giese, Marius Horger, Nisar P. Malek, Michael Bitzer, Sebastian Fetscher, Helmut Lambertz, Lothar Schulz, Ranadip Mandal, Matthias Schlesner, Umut H. Toprak, Kortine Kleinheinz, Stephanie Frank, Karl Roland Ehrenberg, Volker Endris, Roland Penzel, Katja Steiger, Daniela Richter, David Bonekamp, Martina Fröhlich, Barbara Hutter, Barbara Klink, Paula L. Codo, Sebastian Uhrig, Peter Horak, Christoph Heining
Supplementary Table S1 lists potentially clinically relevant somatic alterations in the PDAC patient cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885faf81fceb7309fc8356404d82f45d
https://doi.org/10.1158/2159-8290.22532402.v1
https://doi.org/10.1158/2159-8290.22532402.v1
Autor:
Benedikt Brors, Christof von Kalle, Stefan Frohling, Moritz Koch, Christopher M. Hoffmann, Ulrich Abel, Sebastian M. Dieter, Jürgen Weitz, Manfred G. Schmidt, Claudia R. Ball, Wilko Weichert, Felix Oppel, Frank Bergmann, Jens Werner, Claudia Scholl, Taronish D. Dubash, Karl Roland Ehrenberg, Hanno Glimm, Naveed Ishaque, Friederike Herbst
Publikováno v:
EMBO Molecular Medicine
Although tumor‐initiating cell (TIC) self‐renewal has been postulated to be essential in progression and metastasis formation of human pancreatic adenocarcinoma (PDAC), clonal dynamics of TICs within PDAC tumors are yet unknown. Here, we show tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ba0392a324d3e3cbda48a65fdd69c9
https://doi.org/10.15252/emmm.201607354
https://doi.org/10.15252/emmm.201607354
Autor:
Sebastian Fetscher, Paula L Codo, Claudia Scholl, Wilko Weichert, Frank Bergmann, Oliver Strobel, Kortine Kleinheinz, Martina Fröhlich, Sebastian Uhrig, Marius Horger, Christof von Kalle, Stephanie Frank, Helmut Lambertz, Michael Bitzer, Karl Roland Ehrenberg, Christoph Heining, Stefan Fröhling, Umut H. Toprak, Ranadip Mandal, Lars Feuerbach, Daniela Richter, Volker Endris, Evelin Schröck, Hanno Glimm, Lothar Schulz, David Bonekamp, Claudia R. Ball, Nisar P. Malek, Roland Penzel, Thilo Hackert, Barbara Klink, Christoph Springfeld, Katja Steiger, Peter Horak, Barbara Hutter, Matthias Schlesner, Benedikt Brors, Nathalia A. Giese, Albrecht Stenzinger
We used whole-genome and transcriptome sequencing to identify clinically actionable genomic alterations in young adults with pancreatic ductal adenocarcinoma (PDAC). Molecular characterization of 17 patients with PDAC enrolled in a precision oncology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29a46d494780a9cd2fa508141ed7ed5
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/79185
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/79185
Autor:
Karl Roland Ehrenberg, David Bonekamp, Daniel Huebschmann, Sebastian M. Dieter, David E. Reuss, Christoph Heining, Martina Fröhlich, C.S. Jung, Stefan Fröhling, Stephan E. Wolf, P.A. Federspil, Mark Kriegsmann, Benedikt Brors, Claudia Scholl, Albrecht Stenzinger, Stefan Gröschel, C von Kalle, Wilko Weichert, A. Mavratzas, Peter Schirmacher, Barbara Hutter, H.-P. Schlemmer, Matthias Schlesner, Roland Eils, Roland Penzel, Abbas Agaimy, Hanno Glimm
Sinonasal carcinomas (SNCs) comprise various rare tumor types that are characterized by marked histologic diversity and largely unknown molecular profiles, yet share an overall poor prognosis owing to an aggressive clinical course and frequent late-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1a18129371114a8db72ab5e57d5215
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/79258
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/79258
Autor:
T Urbanik, Dirk Jäger, Matthias Hahn, Henning Schulze-Bergkamen, Ari Waisman, Katharina Becker, Karl Roland Ehrenberg, Thomas Longerich, Marcus A. Wörns, Nadine Hövelmeyer, RJ Boger, Marcus Schuchmann
Publikováno v:
Journal of Hepatology. 57:995-1003
Background & Aims CYLD is a tumor suppressor gene that is mutated in familial cylindromatosis, an autosomal dominant predisposition to tumors of skin appendages. Reduced CYLD expression has been observed in other tumor entities, including hepatocellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95e383a068fb4870ae8e94909684df6
https://doi.org/10.1016/j.jhep.2012.06.017
https://doi.org/10.1016/j.jhep.2012.06.017