Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Karl R. Voigtritter"'
Autor:
Kellie D. Nance, Colleen M. Niswender, Christopher J. Langmead, Aaron M. Bender, Hyekyung P. Cho, Karl R. Voigtritter, P. Jeffrey Conn, Carrie K. Jones, Thomas M. Bridges, Sichen Chang, Patrick R. Gentry, Vincent B. Luscombe, Kaelyn S. Lingenfelter, Alice E. Berizzi, Jordan C. O’Neill, Craig W. Lindsley, Arthur Christopoulos, Charles W. Locuson, Patrick M. Sexton, Xiaoyan Zhan
Publikováno v:
ACS Chemical Neuroscience. 9:1572-1581
The pharmacology of the M5 muscarinic acetylcholine receptor (mAChR) is the least understood of the five mAChR subtypes due to a historic lack of selective small molecule tools. To address this shortcoming, we have continued the optimization effort a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c16e38b3b033988bef5ccd6f3c551fb2
https://doi.org/10.1021/acschemneuro.8b00126
https://doi.org/10.1021/acschemneuro.8b00126
Publikováno v:
Organic Letters
Stereoselective palladium-catalyzed Kumada–Corriu reactions of functionalized alkenyl halides and a variety of Grignard reagents, including those bearing β-hydrogen atoms and sensitive functional groups, can be carried out at room temperature usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5ff12467f1bfe2f0bb54215096a0b1
https://doi.org/10.1021/ol501535w
https://doi.org/10.1021/ol501535w
Autor:
Jerod S. Denton, Haruto Kurata, Rene Raphemot, Anna L. Blobaum, Daniel R. Swale, Craig W. Lindsley, Eric E. Figueroa, Sujay V. Kharade, Jens Meiler, Corey R. Hopkins, Karl R. Voigtritter, Jonathan H. Sheehan
Publikováno v:
ACS chemical neuroscience. 7(7)
The inward rectifier potassium (Kir) channel Kir7.1 (KCNJ13) has recently emerged as a key regulator of melanocortin signaling in the brain, electrolyte homeostasis in the eye, and uterine muscle contractility during pregnancy. The pharmacological to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ff556e6216b56f66292e8397b27bf2
https://pubmed.ncbi.nlm.nih.gov/27184474
https://pubmed.ncbi.nlm.nih.gov/27184474
Publikováno v:
Tetrahedron. 68:3410-3416
CuH-catalyzed 1,2-additions to β,β-disubstituted α,β-unsaturated ketones have been further explored. Asymmetric reductions of enones lacking an α-substituent can be achieved with CuH complexed by DTBM-SEGPHOS in Et 2 O at −25 °C leading to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dc9351c871f48df246bfdba14652ac1
https://doi.org/10.1016/j.tet.2011.10.056
https://doi.org/10.1016/j.tet.2011.10.056
Publikováno v:
Israel Journal of Chemistry. 50:691-695
New technology for palladium-catalyzed cross-couplings between B2pin2 and aryl bromides leading to arylboronates is described. Micellar catalysis serves to enable borylations to take place in water as the only medium at ambient temperatures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0e69be113229e8f6149e1b72a5c93c
https://doi.org/10.1002/ijch.201000045
https://doi.org/10.1002/ijch.201000045
Publikováno v:
Journal of Chemical Education. 87:717-720
Most current organic chemistry textbooks are organized by functional groups and those of us who teach organic chemistry use functional-group organization in our courses but ask students to learn organic chemistry from a mechanistic approach. To enric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0dc9d5c11c41deb57d81674d55b5080
https://doi.org/10.1021/ed100299x
https://doi.org/10.1021/ed100299x
Publikováno v:
Organic Letters. 10:1325-1328
The first examples of unsymmetrical olefin cross-metathesis reactions in water, involving water-insoluble substrates, at room temperature and using commercially available catalysts are reported. The key to success is to include small percentages of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7044fec71bbd9f20f1bc3a59c7ee0e64
https://doi.org/10.1021/ol800028x
https://doi.org/10.1021/ol800028x
Autor:
Roscoe T. H. Linstadt, Bruce H. Lipshutz, James C. Fennewald, M. Hageman, Karl R. Voigtritter, Eric D. Slack
Publikováno v:
ChemInform. 46
Secondary allyl alcohols are unreactive under the investigated conditions allowing the selective oxidation of primary allylic alcohols in the presence of secondary allylic substrates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::439cbfd8f36d7eb04f24da6a7c9c4236
https://doi.org/10.1002/chin.201508107
https://doi.org/10.1002/chin.201508107
Publikováno v:
ChemInform. 46
Stereoselective palladium-catalyzed Kumada–Corriu reactions of functionalized alkenyl halides and a variety of Grignard reagents, including those bearing β-hydrogen atoms and sensitive functional groups, can be carried out at room temperature usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::886dabf8837d136a4c690ba31297f754
https://doi.org/10.1002/chin.201507063
https://doi.org/10.1002/chin.201507063
Autor:
M. Hageman, Roscoe T. H. Linstadt, Bruce H. Lipshutz, Karl R. Voigtritter, James C. Fennewald, Eric D. Slack
Publikováno v:
Chemical communications (Cambridge, England). 50(77)
Allylic and benzylic alcohols can be selectively oxidized to their corresponding aldehydes or ketones in water containing nanoreactors composed of the designer surfactant TPGS-750-M. The oxidation relies on catalytic amounts of CuBr, bpy, and TEMPO,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d01aa71be0d04b31b3ffe03eec1f2ad
https://pubmed.ncbi.nlm.nih.gov/25126656
https://pubmed.ncbi.nlm.nih.gov/25126656