Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Karl Peggs"'
Autor:
Andrew Craig, Martin Forster, Samra Turajlic, Sergio A Quezada, Katy Newton, Karl Peggs, Fong Chan, Karen Matthews, Theres Oakes, Gareth Wilson, Elizabeth Larose Cadieux, Max Salm, Hugh O’Brien
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e8e734fff40a4ec7ba5a3f66dcf9a8fb
Autor:
Stephen Mackinnon, Karl Peggs
Publikováno v:
Revista Brasileira de Hematologia e Hemoterapia, Vol 24, Iss 2, Pp 67-75 (2002)
The dose escalation of chemo-radiotherapy that is achievable with stem cell transplantation is often insufficient to eradicate malignancy, and an associated immune-mediated graft-versus-malignancy effect may be equally important for many diseases. Th
Externí odkaz:
https://doaj.org/article/ad984a56e4b14a8696262329ac660d67
Autor:
Mariam Jamal-Hanjani, Alan Hackshaw, Yenting Ngai, Jacqueline Shaw, Caroline Dive, Sergio Quezada, Gary Middleton, Elza de Bruin, John Le Quesne, Seema Shafi, Mary Falzon, Stuart Horswell, Fiona Blackhall, Iftekhar Khan, Sam Janes, Marianne Nicolson, David Lawrence, Martin Forster, Dean Fennell, Siow-Ming Lee, Jason Lester, Keith Kerr, Salli Muller, Natasha Iles, Sean Smith, Nirupa Murugaesu, Richard Mitter, Max Salm, Aengus Stuart, Nik Matthews, Haydn Adams, Tanya Ahmad, Richard Attanoos, Jonathan Bennett, Nicolai Juul Birkbak, Richard Booton, Ged Brady, Keith Buchan, Arrigo Capitano, Mahendran Chetty, Mark Cobbold, Philip Crosbie, Helen Davies, Alan Denison, Madhav Djearman, Jacki Goldman, Tom Haswell, Leena Joseph, Malgorzata Kornaszewska, Matthew Krebs, Gerald Langman, Mairead MacKenzie, Joy Millar, Bruno Morgan, Babu Naidu, Daisuke Nonaka, Karl Peggs, Catrin Pritchard, Hardy Remmen, Andrew Rowan, Rajesh Shah, Elaine Smith, Yvonne Summers, Magali Taylor, Selvaraju Veeriah, David Waller, Ben Wilcox, Maggie Wilcox, Ian Woolhouse, Nicholas McGranahan, Charles Swanton
Publikováno v:
PLoS Biology, Vol 12, Iss 7, p e1001906 (2014)
The importance of intratumour genetic and functional heterogeneity is increasingly recognised as a driver of cancer progression and survival outcome. Understanding how tumour clonal heterogeneity impacts upon therapeutic outcome, however, is still an
Externí odkaz:
https://doaj.org/article/8c969701acb64396b9868a4b3806e9e1
Autor:
Charles Craddock, Sandeep Nagra, Andrew Peniket, Cassandra Brookes, Laura Buckley, Emmanouil Nikolousis, Nick Duncan, Sudhir Tauro, John Yin, Effie Liakopoulou, Panos Kottaridis, John Snowden, Donald Milligan, Gordon Cook, Eleni Tholouli, Tim Littlewood, Karl Peggs, Paresh Vyas, Fiona Clark, Mark Cook, Stephen MacKinnon, Nigel Russell
Publikováno v:
Haematologica, Vol 95, Iss 6 (2010)
Background Reduced intensity conditioning regimens permit the delivery of a potentially curative graft-versus-leukemia effect in older patients with acute myeloid leukemia. Although T-cell depletion is increasingly used to reduce the risk of graft-ve
Externí odkaz:
https://doaj.org/article/9884d138637b4bb3ae5cc45c8ef54b74
Autor:
Padmanee Sharma, Swetha Anandhan, Bilal A. Siddiqui, Sangeeta Goswami, Sumit K. Subudhi, Jianjun Gao, Karl Peggs, Sergio Quezada, James P. Allison
Publikováno v:
Holland‐Frei Cancer Medicine. :1-22
Autor:
Tim Meyer, Teresa Marafioti, Sergio A. Quezada, Karl Peggs, Christos Toumpanakis, Martyn Caplin, Chrissie Thirlwell, Tu Vinh Luong, Amir Gander, Olagunju Ogunbiyi, Javier Herrero, Lucia Conde, Heli Vaikkinen, Pawan Dhami, Ayse U. Akarca, Alexa Childs, Yien Ning Sophia Wong, Clare Vesely
Supplementary Data from Systematic Evaluation of the Immune Environment of Small Intestinal Neuroendocrine Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b21416a7dce2193bc61d72e5612fc0c
https://doi.org/10.1158/1078-0432.22486557
https://doi.org/10.1158/1078-0432.22486557
Autor:
Tim Meyer, Teresa Marafioti, Sergio A. Quezada, Karl Peggs, Christos Toumpanakis, Martyn Caplin, Chrissie Thirlwell, Tu Vinh Luong, Amir Gander, Olagunju Ogunbiyi, Javier Herrero, Lucia Conde, Heli Vaikkinen, Pawan Dhami, Ayse U. Akarca, Alexa Childs, Yien Ning Sophia Wong, Clare Vesely
Purpose:The immune tumor microenvironment and the potential therapeutic opportunities for immunotherapy in small intestinal neuroendocrine tumors (siNET) have not been fully defined.Experimental Design:Herein, we studied 40 patients with primary and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e62c014a2e3243652c68f6bcf35aad
https://doi.org/10.1158/1078-0432.c.6532341
https://doi.org/10.1158/1078-0432.c.6532341
Autor:
Tim Meyer, Teresa Marafioti, Sergio A. Quezada, Karl Peggs, Christos Toumpanakis, Martyn Caplin, Chrissie Thirlwell, Tu Vinh Luong, Amir Gander, Olagunju Ogunbiyi, Javier Herrero, Lucia Conde, Heli Vaikkinen, Pawan Dhami, Ayse U. Akarca, Alexa Childs, Yien Ning Sophia Wong, Clare Vesely
Supplementary Table from Systematic Evaluation of the Immune Environment of Small Intestinal Neuroendocrine Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33adef37e53562846258689ff6c5ee01
https://doi.org/10.1158/1078-0432.22486527
https://doi.org/10.1158/1078-0432.22486527
Autor:
Julianne Smith, Andrew M. Scharenberg, Martin Pule, Karl Peggs, Sylvain Arnould, Agnès Gouble, Aymeric Duclert, Gordon Weng-Kit Cheung, Justin Eyquem, Céline Lebuhotel, Roman Galetto, Laetitia Lemaire, Cécile Bas, Pierrick Potrel, Sophie Derniame, Isabelle Chion-Sotinel, Diane Le Clerre, Cécile Schiffer-Mannioui, Brian Philip, Laurent Poirot
Supplementary figure S1 : Gene disruption analysis in HEK293 cells. Supplementary figure S2: Optimization of the generation of double KO cells Supplementary table S1: Deep sequencing analysis of TCR-negative cells Supplementary figure S3: Representat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8a0d2010b9ea79650e3d9bcec08e56
https://doi.org/10.1158/0008-5472.22407593
https://doi.org/10.1158/0008-5472.22407593
Autor:
Julianne Smith, Andrew M. Scharenberg, Martin Pule, Karl Peggs, Sylvain Arnould, Agnès Gouble, Aymeric Duclert, Gordon Weng-Kit Cheung, Justin Eyquem, Céline Lebuhotel, Roman Galetto, Laetitia Lemaire, Cécile Bas, Pierrick Potrel, Sophie Derniame, Isabelle Chion-Sotinel, Diane Le Clerre, Cécile Schiffer-Mannioui, Brian Philip, Laurent Poirot
Adoptive immunotherapy using autologous T cells endowed with chimeric antigen receptors (CAR) has emerged as a powerful means of treating cancer. However, a limitation of this approach is that autologous CAR T cells must be generated on a custom-made
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282e688c4450e87665a4af1443c9b0b0
https://doi.org/10.1158/0008-5472.c.6507341
https://doi.org/10.1158/0008-5472.c.6507341