Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Karl P, Nightingale"'
Publikováno v:
Computers & Education. 130:13-25
Supplementary lecture capture is widely used in higher education as the recordings generated are highly valued by students. Here we used a between-subjects, mixed methods study to evaluate whether this approach can support the learning of students di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352c48a64becb911015fa0e232ea78ad
https://doi.org/10.1016/j.compedu.2018.11.006
https://doi.org/10.1016/j.compedu.2018.11.006
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33453 (2012)
Histone deacetylase inhibitors (HDACi) are increasingly used as therapeutic agents, but the mechanisms by which they alter cell behaviour remain unclear. Here we use microarray expression analysis to show that only a small proportion of genes (∼9%)
Externí odkaz:
https://doaj.org/article/807e277a158b4988a06929a0a365d703
Publikováno v:
Computers & Education. 61:185-192
Lecture recordings are increasingly used to supplement lecture attendance within higher education, but their impact on student learning remains unclear. Here we describe a study to evaluate student use of lecture recordings and quantify their impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb5f02baf782c394a3a831c9a5fb4762
https://doi.org/10.1016/j.compedu.2012.09.011
https://doi.org/10.1016/j.compedu.2012.09.011
Autor:
Maaike, Wiersma, Marianne, Bussiere, John A, Halsall, Nil, Turan, Robert, Slany, Bryan M, Turner, Karl P, Nightingale
Publikováno v:
Epigenetics & Chromatin
Background The KMT2A/MLL1 lysine methyltransferase complex is an epigenetic regulator of selected developmental genes, in part through the SET domain-catalysed methylation of H3K4. It is essential for normal embryonic development and haematopoiesis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae83901b222a6a5ce02215eaeaebc59a
https://pubmed.ncbi.nlm.nih.gov/27895715
https://pubmed.ncbi.nlm.nih.gov/27895715
Autor:
Karl P. Nightingale
Publikováno v:
Genome Organization and Function in the Cell Nucleus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73b0318f0ceeae282c84799561666c1a
https://doi.org/10.1002/9783527639991.ch4
https://doi.org/10.1002/9783527639991.ch4
Publikováno v:
FEBS Journal. 275:5635-5647
Histone acetylation plays an integral role in the epigenetic regulation of gene expression. Transcriptional activity reflects the recruitment of opposing classes of enzymes to promoter elements; histone acetyltransferases (EC 2.3.1.48) that deposit a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::250c649b4ae82fb5a76eb66ec7b01a88
https://doi.org/10.1111/j.1742-4658.2008.06689.x
https://doi.org/10.1111/j.1742-4658.2008.06689.x
Publikováno v:
ChemBioChem. 9:499-503
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d03f6a9177398d1594566483d021a90
https://doi.org/10.1002/cbic.200700556
https://doi.org/10.1002/cbic.200700556
Autor:
Karl P. Nightingale, Adamantios Mamais, Matthias Baumann, Peter B. Becker, Joan Boyes, Anton Eberharter
Publikováno v:
Nucleic Acids Research
Targeted chromatin remodelling is essential for many nuclear processes, including the regulation of V(D)J recombination. ATP-dependent nucleosome remodelling complexes are important players in this process whose activity must be tightly regulated. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f42074cdd4fe442255a18d387ef57f19
https://doi.org/10.1093/nar/gkm650
https://doi.org/10.1093/nar/gkm650
Autor:
Susanne Gendreizig, Florian Hollfelder, Charlotte Bradbury, Darren A. White, Bryan M. Turner, Karl P. Nightingale
Publikováno v:
Journal of Biological Chemistry. 282:4408-4416
Histones are subject to a wide variety of post-translational modifications that play a central role in gene activation and silencing. We have used histone modification-specific antibodies to demonstrate that two histone modifications involved in gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bcc652ac71825ea8c5ff487489e426b
https://doi.org/10.1074/jbc.m606773200
https://doi.org/10.1074/jbc.m606773200
Autor:
Karl P. Nightingale
Publikováno v:
Epigenetics for Drug Discovery ISBN: 9781849738828
Over the last decade there has been a revolution in our understanding of gene regulation, and how patterns of gene expression are established and maintained in eukaryotic cells. We now know that many factors – including the chemical modification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01d5645b0240a6fd1b889b7158a42351
https://doi.org/10.1039/9781782628484-00001
https://doi.org/10.1039/9781782628484-00001
