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pro vyhledávání: '"Karl Otto Greulich"'
Autor:
Karl Otto Greulich
Publikováno v:
International Journal of Molecular Sciences, Vol 11, Iss 1, Pp 304-311 (2010)
Single molecule techniques improve our understanding of the photon and light. If the single photon double slit experiment is performed at the “single photon limit” of a multi-atom light source, faint light pulses with more than one photon hamper
Externí odkaz:
https://doaj.org/article/dec49c0c2d2843c4b8632d472a6e9c56
Publikováno v:
Handbuch Alter und Altern ISBN: 9783476024824
Handbuch Alter und Altern
Handbuch Alter und Altern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c242f31ec904373680cead49eda3bf2
https://doi.org/10.1007/978-3-476-05352-7_17
https://doi.org/10.1007/978-3-476-05352-7_17
Autor:
Anne Wilhelm, Karl Otto Greulich, Franziska Jahns, Michael Glei, Henning Mothes, Nadja Jablonowski
Publikováno v:
Molecular Carcinogenesis. 54:249-260
The induction of antioxidant enzymes is an important mechanism in colon cancer chemoprevention, but the response of human colon tissue to butyrate, a gut fermentation product derived from dietary fiber, remains largely unknown. Therefore, our study i
Autor:
Karl Otto Greulich
Publikováno v:
Reports on progress in physics. Physical Society (Great Britain). 80(2)
The use of laser microbeams and optical tweezers in a wide field of biological applications from genomic to immunology is discussed. Microperforation is used to introduce a well-defined amount of molecules into cells for genetic engineering and optic
Autor:
Karl Otto Greulich, Michael Glei, Anne Wilhelm, Henning Mothes, Mariya Radeva, Anja Wölfert, Franziska Jahns
Publikováno v:
Genes & nutrition, 7(2): 235–246
Due to protection of oncogenic proteins from degradation and enhancement of glycolytic phosphometabolites for synthetic processes, respectively, heat shock protein 90 (HSP90) and pyruvate kinase type M2 (PKM2) are important proteins for tumor growth.
Autor:
Karl Otto Greulich
Publikováno v:
Journal of Biophotonics. 4:165-171
This contribution reviews recent applications of micromanipulation, by UV photons, in DNA repair and ageing research as well as in the evaluation of the phototoxicity of drugs. In some cases, micromanipulation is combined with the comet assay, a tech
Autor:
Melanie Struwe, Hans-Jörg Martus, Ulla Plappert-Helbig, Karl Otto Greulich, Willi Suter, Elias Perentes
Publikováno v:
Journal of Investigative Dermatology. 129(3):699-704
The induction and subsequent repair of photochemically induced DNA damage by sparfloxacin was assessed in different tissues of juvenile Wistar rats. The animals were treated once orally with 500 mg kg(-1) of sparfloxacin and irradiated 3 hours later
Publikováno v:
Biopolymers. 23:2559-2571
The protamine thynnine is an arginine-rich protein approximately 30 amino acids long with a tyrosine in the middle of its sequence. Its fluorescence decay kinetics can be described by a biexponential function with lifetimes of 0.52 and 2.1 ns, with a
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 632:44-57
Different classes of chemicals can induce a phototoxic effect by absorbing light energy within the wavelength range of sunlight. The assessment of photo-safety is therefore an obligatory part of the development of new drugs. Ten UV–vis (280–800 n
Autor:
Karl Otto Greulich
Publikováno v:
The Nature of Light: What are Photons? VI.
A model for a self propelling (i.e. massless) photon 1 is based on oscillations of a pair of charges amounting to elementary charge divided by SQRT alpha, where alpha is the fine structure (Sommerfeld) constant. When one assumes a similar model for p