Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Karl Kevala"'
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Abstract Background Repetitive mild traumatic brain injury (mTBI) can result in chronic visual dysfunction. G-protein receptor 110 (GPR110, ADGRF1) is the target receptor of N-docosahexaenoylethanolamine (synaptamide) mediating the anti-neuroinflamma
Externí odkaz:
https://doaj.org/article/18e3ce6773844654a15a2b3071f2fe61
Publikováno v:
Biology Open, Vol 4, Iss 12, Pp 1660-1670 (2015)
Axonogenesis, a process for the establishment of neuron connectivity, is central to brain function. The role of metabolites derived from docosahexaenoic acid (DHA, 22:6n-3) that is specifically enriched in the brain, has not been addressed in axon de
Externí odkaz:
https://doaj.org/article/0617b78927e04c1eb3acec199134fa3a
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86472 (2014)
Omega-3 fatty acids are crucial for proper development and function of the brain where docosahexaenoic acid (DHA), the primary omega-3 fatty acid in the brain, is retained avidly by the neuronal membranes. We investigated the effect of DHA depletion
Externí odkaz:
https://doaj.org/article/fa46d06d54174a9383bc0a9ac5eb9145
Autor:
Heung-Sun Kwon, Karl Kevala, Haohua Qian, Mones Abu-Asab, Samarjit Patnaik, Juan Marugan, Hee-Yong Kim
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5340
It is extremely difficult to achieve functional recovery after axonal injury in the adult central nervous system. The activation of G-protein coupled receptor 110 (GPR110, ADGRF1) has been shown to stimulate neurite extension in developing neurons an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441c9d6defa6d88376ccb5e6d080d2b9
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Repetitive mild traumatic brain injury (mTBI) can result in chronic visual dysfunction. G-protein receptor 110 (GPR110, ADGRF1) is the target receptor of N-docosahexaenoylethanolamine (synaptamide) mediating the anti-neuroinflammatory func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5fa0721973aefb65f4e7af318b3e35c
https://doaj.org/article/18e3ce6773844654a15a2b3071f2fe61
https://doaj.org/article/18e3ce6773844654a15a2b3071f2fe61
Autor:
Nuzhath F. Tajuddin, Michael A. Collins, Karl Kevala, Dimitrios E. Kouzoukas, Hee-Yong Kim, Jennifer A. Schreiber
Publikováno v:
Alcoholism, clinical and experimental researchREFERENCES. 45(12)
Background Repetitive, highly elevated blood alcohol (ethanol) concentrations (BACs) of 350-450 mg/dl over several days cause brain neurodegeneration and coincident neuroinflammation in adult rats that is localized in hippocampus (HC), temporal corte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767a3618547789dc904b031f2cc3a93e
https://pubmed.ncbi.nlm.nih.gov/34719812
https://pubmed.ncbi.nlm.nih.gov/34719812
Publikováno v:
J Neurotrauma
Repeated mild traumatic brain injury (TBI) can cause persistent neuropathological effects and is a major risk factor for chronic traumatic encephalopathy. PUFAs (n-3 polyunsaturated fatty acids) were shown to improve acute TBI outcomes in single-inju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573a94012762b07a9f3a0f9c5e7ae8fb
https://pubmed.ncbi.nlm.nih.gov/33913741
https://pubmed.ncbi.nlm.nih.gov/33913741
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3386, p 3386 (2021)
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3386, p 3386 (2021)
Recovery from axonal injury is extremely difficult, especially for adult neurons. Here, we demonstrate that the activation of G-protein coupled receptor 110 (GPR110, ADGRF1) is a mechanism to stimulate axon growth after injury. N-docosahexaenoylethan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff42b7db32329d91ef47c7fd34282ba
http://europepmc.org/articles/PMC8037074
http://europepmc.org/articles/PMC8037074
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8768, p 8768 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 22
International Journal of Molecular Sciences
Volume 21
Issue 22
We investigated the synthesis of N-docosahexaenoylethanolamine (synaptamide) in neuronal cells from unesterified docosahexaenoic acid (DHA) or DHA-lysophosphatidylcholine (DHA-lysoPC), the two major lipid forms that deliver DHA to the brain, in order
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91047358fc9a0907d5d7cb6bdb955e11
https://www.mdpi.com/1422-0067/21/22/8768
https://www.mdpi.com/1422-0067/21/22/8768
Autor:
Bridget Cunningham, Hee-Yong Kim, Karl Kevala, Carl E. Hunt, Christopher Rouse, Stephanie L. Smith
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 137:1-4
Purpose : Measure concentrations of the neurogenic, pro-neurogenic, pro-synaptogenic and anti-inflammatory mediator N-docosahexaenoylethanolamine (synaptamide) in relation to its precursor docosahexaenoic acid (DHA) in breast milk. Design and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558951c81641ea1df0f53b3c08daddb9
https://doi.org/10.1016/j.plefa.2018.07.016
https://doi.org/10.1016/j.plefa.2018.07.016