Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Karl K Johe"'
Autor:
Guangzhu Zhang, Ying Li, James L. Reuss, Nan Liu, Cuiying Wu, Jingpo Li, Shuangshuang Xu, Feng Wang, Thomas G. Hazel, Miles Cunningham, Hongtian Zhang, Yiwu Dai, Peng Hong, Ping Zhang, Jianghong He, Huiru Feng, Xiangdong Lu, John L. Ulmer, Karl K. Johe, Ruxiang Xu
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 10, Pp 999-1007 (2019)
Abstract NSI‐566 is a stable, primary adherent neural stem cell line derived from a single human fetal spinal cord and expanded epigenetically with no genetic modification. This cell line is being tested in clinical trials in the U.S. for treatment
Externí odkaz:
https://doaj.org/article/112c941a54514a309226862fde02f5f4
Publikováno v:
Cell Transplantation, Vol 23 (2014)
Treatment of central nervous system (CNS) malignancies typically involves radiotherapy to forestall tumor growth and recurrence following surgical resection. Despite the many benefits of cranial radiotherapy, survivors often suffer from a wide range
Externí odkaz:
https://doaj.org/article/a38a4452d72649958c35b8a531901062
Autor:
Karl K, Johe, Gary, Kay, Santosh, Kumar, Katherine E, Burdick, Roger S, McIntyre, George I, Papakostas, Maurizio, Fava
Publikováno v:
Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. 32(3)
NSI-189 phosphate (NSI-189) is a novel neurogenic molecule with pleiotropic properties, including antidepressant, procognitive, synaptoplastic, and neurotrophic activities demonstrated in preclinical studies. Its antidepressant activity is monoamine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ce0e4e2908bb1faa73ef69a94c1089d
https://pubmed.ncbi.nlm.nih.gov/32722729
https://pubmed.ncbi.nlm.nih.gov/32722729
Publikováno v:
Expert Opinion on Investigational Drugs. 26:767-770
Alterations in neurogenic and neurotrophic processes as well as intracellular signalling cascades provides the basis for hypothesizing that neurogenic agents may be therapeutic across multiple RDoC-defined domains (e.g. positive valence systems, gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3df23e0a6e62ba4b2670f921aff449
https://doi.org/10.1080/13543784.2017.1324847
https://doi.org/10.1080/13543784.2017.1324847
Autor:
P Russo, A Drouillard, George I. Papakostas, Max A. Martinson, H Hand, R Kashambwa, Bettina B. Hoeppner, Karl K Johe, G Kay, Martina Flynn, Albert Yeung, Maurizio Fava
Publikováno v:
Molecular Psychiatry
NSI-189 is a novel neurogenic compound independent of monoamine reuptake pathways. This trial evaluated oral NSI-189 as monotherapy in major depressive disorder. To improve signal detection, the sequential-parallel comparison design (SPCD) was chosen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46293cd3290d08037a9dbe7db10c6c56
https://pubmed.ncbi.nlm.nih.gov/30626911
https://pubmed.ncbi.nlm.nih.gov/30626911
Publikováno v:
Baillière's Clinical Haematology. 4:821-848
This chapter has reviewed the nature of antigens of the MNSs blood group system. The structures of the proteins and the molecular features and organization of glycophorin genes were described, emphasizing their domain arrangement and the extensive se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74c93de5d6aef81e6bbd0f36e9e0049d
https://doi.org/10.1016/s0950-3536(06)80032-6
https://doi.org/10.1016/s0950-3536(06)80032-6
Publikováno v:
Brain Research. 473:249-260
Although much evidence exists to support the modulation of neurotransmitter release by adenosine in both the central and peripheral nervous systems, the ionic mechanisms involved in this process are still not established. In our initial series of stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d2892cf842ac37de85b9daa53407b4
https://doi.org/10.1016/0006-8993(88)90854-2
https://doi.org/10.1016/0006-8993(88)90854-2
Autor:
Pollock K; Stem Cell Program and Institute for Regenerative Cures, University of California Davis Health System, Sacramento, CA, USA. kmpollock@ucdavis.edu., Noritake S; Stem Cell Program and Institute for Regenerative Cures, University of California Davis Health System, Sacramento, CA, USA., Imai DM; Comparative Pathology Laboratory, University of California Davis, School of Veterinary Medicine, Davis, CA, USA., Pastenkos G; Comparative Pathology Laboratory, University of California Davis, School of Veterinary Medicine, Davis, CA, USA., Olson M; Stem Cell Program and Institute for Regenerative Cures, University of California Davis Health System, Sacramento, CA, USA., Cary W; Stem Cell Program and Institute for Regenerative Cures, University of California Davis Health System, Sacramento, CA, USA., Yang S; Stem Cell Program and Institute for Regenerative Cures, University of California Davis Health System, Sacramento, CA, USA., Fierro FA; Stem Cell Program and Institute for Regenerative Cures, University of California Davis Health System, Sacramento, CA, USA., White J; Stem Cell Program and Institute for Regenerative Cures, University of California Davis Health System, Sacramento, CA, USA., Graham J; Stem Cell Program and Institute for Regenerative Cures, University of California Davis Health System, Sacramento, CA, USA., Dahlenburg H; Stem Cell Program and Institute for Regenerative Cures, University of California Davis Health System, Sacramento, CA, USA., Johe K; ReMotor Therapeutics, Inc., San Diego, CA, USA., Nolta JA; Stem Cell Program and Institute for Regenerative Cures, University of California Davis Health System, Sacramento, CA, USA.
Publikováno v:
Scientific reports [Sci Rep] 2023 Oct 27; Vol. 13 (1), pp. 18439. Date of Electronic Publication: 2023 Oct 27.
Autor:
Zhang G; Affiliated BaYi Brain Hospital, Army General Hospital of PLA, Beijing, China., Cunningham M; Laboratory for Neural Reconstruction, McLean Hospital, Harvard Medical School, Belmont, Massachusetts., Zhang H; Affiliated BaYi Brain Hospital, Army General Hospital of PLA, Beijing, China., Dai Y; Affiliated BaYi Brain Hospital, Army General Hospital of PLA, Beijing, China., Zhang P; Affiliated BaYi Brain Hospital, Army General Hospital of PLA, Beijing, China., Ge G; Affiliated BaYi Brain Hospital, Army General Hospital of PLA, Beijing, China., Wang B; Affiliated BaYi Brain Hospital, Army General Hospital of PLA, Beijing, China., Bai M; Affiliated BaYi Brain Hospital, Army General Hospital of PLA, Beijing, China., Hazel T; Neuralstem Inc., Germantown, Maryland., Johe K; Neuralstem Inc., Germantown, Maryland., Xu R; Affiliated BaYi Brain Hospital, Army General Hospital of PLA, Beijing, China.
Publikováno v:
Operative neurosurgery (Hagerstown, Md.) [Oper Neurosurg (Hagerstown)] 2020 May 01; Vol. 18 (5), pp. 503-510.
Autor:
Marsala M; Neuroregeneration Laboratory, Department of Anesthesiology, University of California, San Diego, La Jolla, California., Kamizato K; Neuroregeneration Laboratory, Department of Anesthesiology, University of California, San Diego, La Jolla, California.; Department of Anesthesia, University of Ryukyus, Okinawa, Japan., Tadokoro T; Neuroregeneration Laboratory, Department of Anesthesiology, University of California, San Diego, La Jolla, California.; Department of Anesthesia, University of Ryukyus, Okinawa, Japan., Navarro M; Neuroregeneration Laboratory, Department of Anesthesiology, University of California, San Diego, La Jolla, California., Juhas S; Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Libechov, Czech Republic., Juhasova J; Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Libechov, Czech Republic., Marsala S; Neuroregeneration Laboratory, Department of Anesthesiology, University of California, San Diego, La Jolla, California., Studenovska H; Department of Biomaterials and Bioanalogous Systems, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic., Proks V; Department of Biomaterials and Bioanalogous Systems, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic., Hazel T; Neuralstem Inc., Germantown, Maryland., Johe K; Neuralstem Inc., Germantown, Maryland., Kakinohana M; Department of Anesthesia, University of Ryukyus, Okinawa, Japan., Driscoll S; Gene Expression Laboratory, Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, California., Glenn T; Gene Expression Laboratory, Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, California., Pfaff S; Gene Expression Laboratory, Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, California., Ciacci J; Department of Neurosurgery, University of California, San Diego, La Jolla, California.
Publikováno v:
Stem cells translational medicine [Stem Cells Transl Med] 2020 Feb; Vol. 9 (2), pp. 177-188. Date of Electronic Publication: 2019 Dec 04.