Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Karl J. Espe"'
Autor:
Jason W Bauer, Emily C Baechler, Michelle Petri, Franak M Batliwalla, Dianna Crawford, Ward A Ortmann, Karl J Espe, Wentian Li, Dhavalkumar D Patel, Peter K Gregersen, Timothy W Behrens
Publikováno v:
PLoS Medicine, Vol 3, Iss 12, p e491 (2006)
Systemic lupus erythematosus (SLE) is a serious systemic autoimmune disorder that affects multiple organ systems and is characterized by unpredictable flares of disease. Recent evidence indicates a role for type I interferon (IFN) in SLE pathogenesis
Externí odkaz:
https://doaj.org/article/2d6dc0c234ef4c04b2b508fdd016e69f
Autor:
Peter K. Gregersen, Timothy W. Behrens, Lindsey A. Criswell, Patrick M. Gaffney, Robert R. Graham, Ward A. Ortmann, Peter R. Rodine, Ethan M. Lange, Chieko Kyogoku, Stephanie R Beck, Carl D. Langefeld, Adrienne H. Williams, Kathy L. Moser, Karl J. Espe, John B. Harley
Publikováno v:
European Journal of Human Genetics. 15:823-830
The human leukocyte antigen (HLA) Class II antigen presentation alleles DR and DQ are associated with susceptibility to systemic lupus erythematosus (SLE) and the production of lupus-related autoantibodies. Here, we explore the effect of different co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef68fd1d801f607b41f5ac3ef333808
https://doi.org/10.1038/sj.ejhg.5201827
https://doi.org/10.1038/sj.ejhg.5201827
Autor:
Peter K. Gregersen, Timothy W. Behrens, Sheng Yung P Chang, Emily C. Baechler, Patrick M. Gaffney, Ward A. Ortmann, George Karypis, Franak Batliwalla, S. Balasubramanian, Ann B. Begovich, J. P. Chan, Karl J. Espe, K. M. Hughes, Kathy L. Moser
Publikováno v:
Genes & Immunity. 5:347-353
Monitoring of gene and protein expression in peripheral blood cells has significant potential for improving the diagnosis and therapy of many human diseases. As genomic-scale microarray and proteomic technologies are applied to peripheral blood, it i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d79e8262897babbdf75df177d3ee0b5
https://doi.org/10.1038/sj.gene.6364098
https://doi.org/10.1038/sj.gene.6364098
Autor:
Franak Batliwalla, George Karypis, Timothy W. Behrens, Ward A. Ortmann, Katherine B. Shark, Emily C. Baechler, Patrick M. Gaffney, Peter K. Gregersen, Karl J. Espe, William J. Grande, Vivek Kapur, Karis M. Hughes
Publikováno v:
Proceedings of the National Academy of Sciences. 100:2610-2615
Systemic lupus erythematosus (SLE) is a complex, inflammatory autoimmune disease that affects multiple organ systems. We used global gene expression profiling of peripheral blood mononuclear cells to identify distinct patterns of gene expression that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e8b8b8d81241f8657d2608b4cb591a
https://doi.org/10.1073/pnas.0337679100
https://doi.org/10.1073/pnas.0337679100
Autor:
Ward A. Ortmann, Steven R. Ytterberg, Karl J. Espe, Ann M. Reed, Timothy W. Behrens, Emily C. Baechler, Jason W. Bauer, Catherine Slattery, Jill Novitzke, Peter K. Gregersen
Recent studies have shown increased expression of interferon (IFN)-regulated genes in the peripheral blood cells of patients with systemic lupus erythematosus. A similar interferon signature has been observed in affected muscle tissue from patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0affdf6ba01dfef43f3d80077434a5c3
https://europepmc.org/articles/PMC1869622/
https://europepmc.org/articles/PMC1869622/
Autor:
Carolyn Meyer, John B. Harley, A. N. Leiran, Courtney Gray-McGuire, Kathy L. Moser, Ward A. Ortmann, Timothy W. Behrens, Morris Reichlin, Gail R. Bruner, Paula S. Ramos, Jennifer A. Kelly, Judith A. James, Patrick M. Gaffney, Bahram Namjou, Carl D. Langefeld, Karl J. Espe
Publikováno v:
Genes and immunity. 7(5)
Autoantibodies are clinically relevant biomarkers for numerous autoimmune disorders. The genetic basis of autoantibody production in systemic lupus erythematosus (SLE) and other autoimmune diseases is poorly understood. In this study, we characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2547a1e30a36bcd9426e3dc3803ee89
https://pubmed.ncbi.nlm.nih.gov/16775618
https://pubmed.ncbi.nlm.nih.gov/16775618
Autor:
Peter K. Gregersen, Jason W. Bauer, Timothy W. Behrens, Ward A. Ortmann, Michelle Petri, Dianna M. Crawford, Karl J. Espe, Franak Batliwalla, Emily C. Baechler, Dhavalkumar D. Patel, Wentian Li
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 3, Iss 12, p e491 (2006)
PLoS Medicine, Vol 3, Iss 12, p e491 (2006)
Background Systemic lupus erythematosus (SLE) is a serious systemic autoimmune disorder that affects multiple organ systems and is characterized by unpredictable flares of disease. Recent evidence indicates a role for type I interferon (IFN) in SLE p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2bec97956c611a080060090aaa7e1a
https://pubmed.ncbi.nlm.nih.gov/17177599
https://pubmed.ncbi.nlm.nih.gov/17177599
Autor:
Carl D. Langefeld, Philip E. Stuart, Damini Jawaheer, Linda E. Green, Peter R. Rodine, Katherine B. Shark, James T. Elder, Rajan P. Nair, Timothy W. Behrens, Peter K. Gregersen, Teodorica L. Bugawan, Ward A. Ortmann, Patrick M. Gaffney, Stephen S. Rich, Emily C. Baechler, Karl J. Espe, Richard A. King, Robert R. Graham, Kathy L. Moser, Kristine E. Rohlf, Henry A. Erlich, Scott A. Selby
Publikováno v:
American journal of human genetics. 71(3)
Human leukocyte antigen (HLA) class I and class II alleles are implicated as genetic risk factors for many autoimmune diseases. However, the role of the HLA loci in human systemic lupus erythematosus (SLE) remains unclear. Using a dense map of polymo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3412392cf50be84f3f35700cbd662a
https://pubmed.ncbi.nlm.nih.gov/12145745
https://pubmed.ncbi.nlm.nih.gov/12145745