Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Karl J Jepsen"'
Autor:
Karl J Jepsen, Erin MR Bigelow, Michael A Casden, Robert W Goulet, Kathryn Kennedy, Samantha Hertz, Chandan Kadur, Bonnie T Nolan, Kerry Richards‐McCullough, Steffenie Merillat, Carrie A Karvonen‐Gutierrez, Gregory Clines, Todd L Bredbenner
Publikováno v:
JBMR Plus, Vol 7, Iss 3, Pp n/a-n/a (2023)
ABSTRACT Bone mineral density (BMD) is heavily relied upon to reflect structural changes affecting hip strength and fracture risk. Strong correlations between BMD and strength are needed to provide confidence that structural changes are reflected in
Externí odkaz:
https://doaj.org/article/6ff9796dfb1f49a48dcceb8149dcc001
Autor:
Noah J Mathis, Emily N Adaniya, Lauren M Smith, Alexander G Robling, Karl J Jepsen, Stephen H Schlecht
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214520 (2019)
Administration of sclerostin-neutralizing antibody (Scl-Ab) treatment has been shown to elicit an anabolic bone response in growing and adult mice. Prior work characterized the response of individual mouse strains but did not establish whether the im
Externí odkaz:
https://doaj.org/article/66efcefa612445658600f2e15b22f593
Autor:
Hayden-William Courtland, Sebastien Elis, Yingjie Wu, Hui Sun, Clifford J Rosen, Karl J Jepsen, Shoshana Yakar
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e14762 (2011)
Insulin-like growth factor-1 (IGF-1) plays a critical role in the development of the growing skeleton by establishing both longitudinal and transverse bone accrual. IGF-1 has also been implicated in the maintenance of bone mass during late adulthood
Externí odkaz:
https://doaj.org/article/130f333683004b12aec827cf987a5fc3
Autor:
Efrat Eliyahu, Theodore Wolfson, Yi Ge, Karl J Jepsen, Edward H Schuchman, Calogera M Simonaro
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22447 (2011)
Although enzyme replacement therapy (ERT) is available for several lysosomal storage disorders, the benefit of this treatment to the skeletal system is very limited. Our previous work has shown the importance of the Toll-like receptor 4/TNF-alpha inf
Externí odkaz:
https://doaj.org/article/c966fcec0c3140f3ba9d1a76ce1db947
Autor:
Cathleen L. Raggio, Nancy Pleshko, No'ad Shanas, Jack Oswald, William Querido, Karl J. Jepsen, Erin Carter
Publikováno v:
Applied Spectroscopy. 76:416-427
Applications of vibrational spectroscopy to assess bone disease and therapeutic interventions are continually advancing, with tissue mineral and protein composition frequently investigated. Here, we used two spectroscopic approaches for determining b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff425aa18dcfad59c21a20ec34d76330
https://doi.org/10.1177/00037028211055477
https://doi.org/10.1177/00037028211055477
Publikováno v:
Developmental Medicine & Child Neurology. 64:469-475
Aim To understand associations among bone mineral density (BMD), bone mineral content (BMC), and bone area, and their association with fractures in adults with cerebral palsy (CP). Method This retrospective cohort study included 78 adults with CP wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd17f7704596bf49ca1e8e866d89e390
https://doi.org/10.1111/dmcn.15093
https://doi.org/10.1111/dmcn.15093
Publikováno v:
Current Osteoporosis Reports. 19:542-552
Image-based measurements of bone integrity are used to estimate failure properties and clinical fracture risk. This paper (1) reviews recent imaging studies that have enhanced our understanding of the mechanical pathways to bone fracture and (2) disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ad2734770c2f963bbcff1ba0938161b
https://doi.org/10.1007/s11914-021-00700-z
https://doi.org/10.1007/s11914-021-00700-z
Autor:
Karl J. Jepsen, Daniella M. Patton, Colin T. Martin, Stephen H Schlecht, Michael Casden, Danielle N Ochocki, Edward M. Wojtys, James A. Ashton-Miller
Publikováno v:
J Orthop Res
Despite poor graft integration among some patients that undergo an anterior cruciate ligament (ACL) reconstruction, there has been little consideration of the bone quality into which the ACL femoral tunnel is drilled and the graft is placed. Bone min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba7e6c464a6b1fcb4dee7b9bd960680
https://doi.org/10.1002/jor.25130
https://doi.org/10.1002/jor.25130
Publikováno v:
Lab animal. 51(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b4d4db9a1d284f004382d8b970a369
https://pubmed.ncbi.nlm.nih.gov/35641622
https://pubmed.ncbi.nlm.nih.gov/35641622
Autor:
Morgan W. Bolger, Genevieve E. Romanowicz, Erin M.R. Bigelow, Ferrous S. Ward, Antonio Ciarelli, Karl J. Jepsen, David H. Kohn
Publikováno v:
Bone
Bone strength is generally thought to decline with aging and prior work has compared traits between younger and older cohorts to identify the structural and compositional changes that contributes to fracture risk with age. However, for men, the major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c505ea9efd5f41b6bed12d2891624e
https://pubmed.ncbi.nlm.nih.gov/35817317
https://pubmed.ncbi.nlm.nih.gov/35817317