Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Karl J Frontzek"'
Autor:
Marco Losa, Marc Emmenegger, Pierre De Rossi, Patrick M Schürch, Tetiana Serdiuk, Niccolò Pengo, Danaëlle Capron, Dimitri Bieli, Niklas Bargenda, Niels J Rupp, Manfredi C Carta, Karl J Frontzek, Veronika Lysenko, Regina R Reimann, Petra Schwarz, Mario Nuvolone, Gunilla T Westermark, K Peter R Nilsson, Magdalini Polymenidou, Alexandre PA Theocharides, Simone Hornemann, Paola Picotti, Adriano Aguzzi
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2024-2042 (2024)
Abstract Extracellularly released molecular inflammasome assemblies -ASC specks- cross-seed Aβ amyloid in Alzheimer’s disease. Here we show that ASC governs the extent of inflammation-induced amyloid A (AA) amyloidosis, a systemic disease caused b
Externí odkaz:
https://doaj.org/article/361701b3ccf5457e8ccf997a37e06f01
Autor:
Daniel Kirschenbaum, Ehsan Dadgar‐Kiani, Francesca Catto, Fabian F Voigt, Chiara Trevisan, Oliver Bichsel, Hamid Shirani, K Peter R Nilsson, Karl J Frontzek, Paolo Paganetti, Fritjof Helmchen, Jin Hyung Lee, Adriano Aguzzi
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 1, Pp n/a-n/a (2023)
Abstract Many efforts targeting amyloid‐β (Aβ) plaques for the treatment of Alzheimer's Disease thus far have resulted in failures during clinical trials. Regional and temporal heterogeneity of efficacy and dependence on plaque maturity may have
Externí odkaz:
https://doaj.org/article/b22aabc15970409aa99a43cfa57a5c79
Autor:
Marco Losa, Marc Emmenegger, Pierre De Rossi, Patrick M Schürch, Tetiana Serdiuk, Niccolò Pengo, Danaëlle Capron, Dimitri Bieli, Niels J Rupp, Manfredi C Carta, Karl J Frontzek, Veronika Lysenko, Regina R Reimann, Asvin KK Lakkaraju, Mario Nuvolone, Gunilla T Westermark, K. Peter R. Nilsson, Magdalini Polymenidou, Alexandre P. A. Theocharides, Simone Hornemann, Paola Picotti, Adriano Aguzzi
ASC-containing inflammasomes form specks, extracellular aggregates which enhance the aggregation of Aβ amyloid in Alzheimer’s disease. This raises the question whether ASC participates to additional aggregation proteinopathies. Here we show that A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b0ee4ed691ab2d5feffffe4a9f423b1
https://doi.org/10.1101/2021.05.01.442282
https://doi.org/10.1101/2021.05.01.442282
