Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Karl Herbert Schäfer"'
Autor:
Muhammad Irfan Masood, Karl Herbert Schäfer, Mahrukh Naseem, Maximilian Weyland, Peter Meiser
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237025 (2020)
Troxerutin (TRX) is a water-soluble flavonoid which occurs commonly in the edible plants. Recent studies state that TRX improves the functionality of the nervous system and neutralizes Amyloid-ß induced neuronal toxicity. In this study, an in vitro
Externí odkaz:
https://doaj.org/article/804e6539e0e7462e890e23febe669a48
Autor:
Muhammad Sarfraz, Sharoon Griffin, Tamara Gabour Sad, Rama Alhasan, Muhammad Jawad Nasim, Muhammad Irfan Masood, Karl Herbert Schäfer, Chukwunonso E.C.C. Ejike, Cornelia M. Keck, Claus Jacob, Azubuike P. Ebokaiwe
Publikováno v:
Antioxidants, Vol 7, Iss 4, p 60 (2018)
Nanosizing represents a straight forward technique to unlock the biological activity of complex plant materials. The aim of this study was to develop herbal nanoparticles with medicinal value from dried leaves and stems of Loranthus micranthus with t
Externí odkaz:
https://doaj.org/article/c4da007096a946dc8d077ea0e4cf545c
Autor:
Peter Verstraelen, Samuel Van Remoortel, Nouchin De Loose, Rosanne Verboven, Gerardo Garcia-Diaz Barriga, Anne Christmann, Manuela Gries, Shingo Bessho, Jing Li, Carmen Guerra, Çagla Tükel, Sales Ibiza Martinez, Karl-Herbert Schäfer, Jean-Pierre Timmermans, Winnok H. De Vos
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 1, Pp 89-104 (2024)
Background & Aims: Mounting evidence suggests the gastrointestinal microbiome is a determinant of peripheral immunity and central neurodegeneration, but the local disease mechanisms remain unknown. Given its potential relevance for early diagnosis an
Externí odkaz:
https://doaj.org/article/9e6f75de89f84982823a97136cab22fe
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 984 (2024)
Pregnancy is a particularly vulnerable period for the growing fetus, when exposure to toxic agents, especially in the early phases, can decisively harm embryo development and compromise the future health of the newborn. The inclusion of various chemi
Externí odkaz:
https://doaj.org/article/9366269868864cd9be1a3faae25f6019
Autor:
Enas Zoheer Elkrewi, Ahmad A. Al Abdulqader, Rasul Khasanov, Silke Maas-Omlor, Michael Boettcher, Lucas M. Wessel, Karl-Herbert Schäfer, María Ángeles Tapia-Laliena
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 992 (2024)
Hirschsprung’s disease (HSCR, incidence 1/5000 live births) is caused by the failure of neural crest-derived precursors to migrate, survive, proliferate, or differentiate during the embryonic development of the Enteric Nervous System (ENS), which c
Externí odkaz:
https://doaj.org/article/7a223f8308cd4090847aa434947ecec7
Autor:
Yogesh Singh, Christoph Trautwein, Joan Romani, Madhuri S. Salker, Peter H. Neckel, Isabel Fraccaroli, Mahkameh Abeditashi, Nils Woerner, Jakob Admard, Achal Dhariwal, Morten K. D. Dueholm, Karl-Herbert Schäfer, Florian Lang, Daniel E. Otzen, Hilal A. Lashuel, Olaf Riess, Nicolas Casadei
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-28 (2023)
Abstract Background Braak’s hypothesis states that sporadic Parkinson’s disease (PD) follows a specific progression of pathology from the peripheral to the central nervous system, and this progression can be monitored by detecting the accumulatio
Externí odkaz:
https://doaj.org/article/a3d79a113d0147b78484a1d4a475b1f5
Autor:
Bharat Nowduri, Steven Schulte, Negin Adavoudi Jolfaei, Dominique Decker, Holger Rabe, Karl‐Herbert Schäfer, Monika Saumer
Publikováno v:
Advanced Materials Interfaces, Vol 10, Iss 16, Pp n/a-n/a (2023)
Abstract Microelectrode surfaces covered with nanostructures derived from components of extracellular matrix, such as collagen fibers, have shown immense beneficial effects in promoting neuronal growth and cellular signaling. Synthetic nanostructures
Externí odkaz:
https://doaj.org/article/ba26519bbf904ffea336e5b61809aca2
Autor:
Sabine Heumüller-Klug, Kristina Maurer, María Á. Tapia-Laliena, Carsten Sticht, Anne Christmann, Handan Mörz, Rasul Khasanov, Elvira Wink, Steven Schulte, Wolfgang Greffrath, Rolf-Detlef Treede, Lucas M. Wessel, Karl-Herbert Schäfer
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Impairment of both the central and peripheral nervous system is a major cause of mortality and disability. It varies from an affection of the brain to various types of enteric dysganglionosis. Congenital enteric dysganglionosis is chara
Externí odkaz:
https://doaj.org/article/0f6353f60cbc4231843e2f54d8222b42
Autor:
Severin Weis, Marcus M. Unger, Markus Egert, Alexandra Meisner, Klaus Faßbender, Andreas Schwiertz, Karl-Herbert Schäfer, Sylvia Schnell, Anouck Becker
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-7 (2021)
NPJ Parkinson's Disease
NPJ Parkinson's Disease
Parkinson’s disease (PD) is one of the most common neurodegenerative disease, and is so far not considered curable. PD patients suffer from several motor and non-motor symptoms, including gastrointestinal dysfunctions and alterations of the enteric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a833e0e8d2665e71f2923b91cf2c32
https://doaj.org/article/b43a5de64b4c404a96985bf3fa5b0f2a
https://doaj.org/article/b43a5de64b4c404a96985bf3fa5b0f2a
Autor:
Manuela Gries, Cornelia M. Keck, Steven Schulte, Monika Martin, Pascal L Stahr, Karl-Herbert Schäfer, Anne Christmann, Sven Ingebrandt, Patrik Scholz, Jessica Ka-Yan Law, Rainer Lilischkis
Publikováno v:
Biological Chemistry. 403:103-122
Motoric disturbances in Parkinson’s disease (PD) derive from the loss of dopaminergic neurons in the substantia nigra. Intestinal dysfunctions often appear long before manifestation of neuronal symptoms, suggesting a strong correlation between gut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cacfc674c80ef3658a7dcf3332c10a98
https://doi.org/10.1515/hsz-2021-0259
https://doi.org/10.1515/hsz-2021-0259