Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Karl Heinz Scheidtmann"'
Autor:
Meike Boosen, Susanne Illenberger, Jan Kubicek, Susanne Vetterkind, Ute Preuss, Karl-Heinz Scheidtmann
Publikováno v:
Molecular Biology of the Cell. 20:4010-4020
Prostate apoptosis response-4 (Par-4) was initially identified as a gene product up-regulated in prostate cancer cells undergoing apoptosis. In rat fibroblasts, coexpression of Par-4 and its interaction partner DAP-like kinase (Dlk, which is also kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45247bb55701e6d034d3f6280a765b92
https://doi.org/10.1091/mbc.e09-02-0173
https://doi.org/10.1091/mbc.e09-02-0173
Autor:
Michael Böhringer, Anja Restle, Martin Färber, Carsten Müller-Tidow, Cindy Baumann, Lisa Wiesmüller, Karl Heinz Scheidtmann
Publikováno v:
Nucleic Acids Research
Regulation of homologous recombination (HR) represents the best-characterized DNA repair function of p53. The role of p53 phosphorylation in DNA repair is largely unknown. Here, we show that wild-type p53 repressed repair of DNA double-strand breaks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a5b57d06c90dadb1cfc14d5ebd6a70
https://doi.org/10.1093/nar/gkn503
https://doi.org/10.1093/nar/gkn503
Publikováno v:
Oncogene. 27:3292-3300
The androgen receptor (AR) is a ligand-dependent transcription factor that plays a crucial role in the development and homeostasis of the prostate and in prostate cancer. The transcriptional activity of AR is mediated by interaction with multiple co-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f294b2e1731dd126092b78719223c4
https://doi.org/10.1038/sj.onc.1210995
https://doi.org/10.1038/sj.onc.1210995
Publikováno v:
bchm. 388:569-582
AATF/Che-1 is a coactivator of several transcription factors, including steroid hormone receptors. In search of novel interaction partners of AATF, we identified BLOS2 (BLOC1S2, also termed Ceap) from a rat cDNA library. BLOS2 is extremely conserved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224d55810ffbd2de16bbaf163ef3635b
https://doi.org/10.1515/bc.2007.073
https://doi.org/10.1515/bc.2007.073
Autor:
Karl Heinz Scheidtmann
Publikováno v:
Signal Transduction. 7:248-259
Dlk/ZIP kinase is a member of the DAP kinase family which has been implicated in apoptosis. However, Dlk/ZIP kinase does not induce apoptosis per se. Rather, downregulation of Dlk/ZIP kinase by siRNA results in apoptosis and multinucleated cells sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::039882b9dbafdc705301077e0fd6a63c
https://doi.org/10.1002/sita.200600112
https://doi.org/10.1002/sita.200600112
Publikováno v:
European Journal of Cell Biology. 82:447-459
DAP-like kinase (Dlk) is a nuclear serine/threonine-specific kinase which has been implicated in apoptosis. However, induction of apoptosis by Dlk requires its relocation to the cytoplasm, particularly association with the actin cytoskeleton, which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a6cdceaf71fde5c196d8664c24f3e6
https://doi.org/10.1078/0171-9335-00332
https://doi.org/10.1078/0171-9335-00332
Apoptosis antagonizing transcription factor AATF is a novel coactivator of nuclear hormone receptors
Publikováno v:
Signal Transduction. 3:17-25
Apoptosis antagonizing transcription factor AATF was identified as interaction partner of Dlk/ZIP kinase and shown to exhibit transactivation activity in Gal4-based reporter gene expression assays. The human ortholog Che-1 was independently isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::924e1235205020bbdcdd4fbaa8762121
https://doi.org/10.1002/sita.200300020
https://doi.org/10.1002/sita.200300020
Publikováno v:
European Journal of Cancer. 39:249-256
Dlk/ZIP kinase is one of five members of the death associated protein (DAP) kinase family. DAP kinase is able to induce apoptosis in a p19ARF/p53-dependent manner. We elucidated the potential role of the p19ARF/p53 pathway in Dlk/ZIP kinase-triggered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec7d3657e0965a93112d94156f67e6d
https://doi.org/10.1016/s0959-8049(02)00477-x
https://doi.org/10.1016/s0959-8049(02)00477-x
Autor:
Jochen H. M. Prehn, D Kögel, Harry Engemann, Claus Reimertz, Karl Heinz Scheidtmann, Monika Poppe, P Mech, M C Frühwald
Publikováno v:
British Journal of Cancer
Dlk/ZIP kinase is a member of the Death Associated Protein (DAP) kinase family of pro-apoptotic serine/threonine kinases that have been implicated in regulation of apoptosis and tumour suppression. Expression of both Dlk/ZIP kinase and its interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962a7b31ea553093f79b7ebb8985c776
https://doi.org/10.1054/bjoc.2001.2158
https://doi.org/10.1054/bjoc.2001.2158
Publikováno v:
BioEssays. 23:352-358
The DAP (Death Associated Protein) kinase family is a novel subfamily of pro-apoptotic serine/threonine kinases. All five DAP kinase family members identified to date are ubiquitously expressed in various tissues and are capable of inducing apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93b627379e75a9cf4f450d913ba78c32
https://doi.org/10.1002/bies.1050
https://doi.org/10.1002/bies.1050