Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Karl G, Hock"'
Autor:
Junedh M. Amrute, Alexandra M. Perry, Gautam Anand, Carlos Cruchaga, Karl G. Hock, Christopher W. Farnsworth, Gwendalyn J. Randolph, Kory J. Lavine, Ashley L. Steed
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Infection with SARS-CoV-2 results in activation of multiple immune cell types in situ but also in the peripheral blood compartment. Here the authors apply single cell sequencing and machine learning to characterise the response and link this to confe
Externí odkaz:
https://doaj.org/article/7ea61ba9dd2a4e94a5c0a03717c98dc7
Autor:
Tingting Li, Sumanth Gandra, Kimberly A. Reske, Margaret A. Olsen, Silvana Bommarito, Candace Miller, Karl G. Hock, Claire A. Ballman, Christina Su, Na Le Dang, Jennie H. Kwon, David K. Warren, Victoria J. Fraser, Christopher W. Farnsworth, for the Centers for Disease Control and Prevention Epicenters Program
Publikováno v:
Antimicrobial Stewardship & Healthcare Epidemiology, Vol 2 (2022)
Abstract Objective: Patients on dialysis are at high risk for severe COVID-19 and associated morbidity and mortality. We examined the humoral response to SARS-CoV-2 mRNA vaccine BNT162b2 in a maintenance dialysis population. Design: Single-center
Externí odkaz:
https://doaj.org/article/161490c2cc85409fa60822025f6e2b16
Autor:
Sumanth Gandra, Tingting Li, Kimberly A. Reske, Kate Peacock, Karl G. Hock, Silvana Bommarito, Candace Miller, Henry Stewart, Na Le Dang, Christopher W. Farnsworth, Margaret A. Olsen, Jennie H. Kwon, David K. Warren, Victoria J. Fraser, for the CDC Prevention Epicenters Program
Publikováno v:
Antimicrobial Stewardship & Healthcare Epidemiology, Vol 2 (2022)
In this prospective, longitudinal study, we examined the risk factors for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection among a cohort of chronic hemodialysis (HD) patients and healthcare personnel (HCPs) over a 6-month period.
Externí odkaz:
https://doaj.org/article/d385368d021241dfae7fd3c4e59a01f0
Autor:
Catherine L Omosule, Karl G Hock, Claire Dalton, Anthony Scalpati, Ann M Gronowski, Aigars Brants, Christopher W Farnsworth
Publikováno v:
The Journal of Applied Laboratory Medicine.
Background The Freelite assay (The Binding Site) is utilized to quantify serum immunoglobulin free light chains (sFLC), which is crucial for diagnosing and monitoring plasma cell dyscrasias (PCDs). Using the Freelite test, we compared methods and eva
Publikováno v:
The Journal of Applied Laboratory Medicine. 7:827-833
Background Serological assays for SARS-CoV-2 are important tools for diagnosis in patients with negative RT-PCR testing, pediatric patients with multisystem inflammatory syndrome, and serosurveillance studies. However, lateral flow-based serological
Autor:
Elitza S. Theel, Jane A. O’Halloran, Charles W. Goss, James Brett Case, Adriana M Rauseo, Michael S. Diamond, Jeffrey P. Henderson, Karl G. Hock, Ali H. Ellebedy, Rachel M. Presti, Rita E. Chen, Christopher W Farnsworth
Publikováno v:
Transfusion
medRxiv
article-version (status) pre
article-version (number) 1
medRxiv
article-version (status) pre
article-version (number) 1
Background The COVID‐19 pandemic has been accompanied by the largest mobilization of therapeutic convalescent plasma (CCP) in over a century. Initial identification of high titer units was based on dose–response data using the Ortho VITROS IgG as
Autor:
Christopher W Farnsworth, Jennie H. Kwon, Tingting Li, Victoria J. Fraser, Karl G. Hock, Candace Miller, Na Le Dang, David K. Warren, Sumanth Gandra, Kimberly A. Reske, Margaret A. Olsen
Publikováno v:
Kidney360
Key Points Increased risk of SARS-CoV-2 infection was associated with community prevalence. Increased risk of SARS-CoV-2 infection was associated with exposure to infected family members and personal infection prevention measures
Autor:
Karl G. Hock, Emily Schindler, Marian Dribus, Brian Duffy, Chang Liu, Loren Gragert, Christopher W Farnsworth
Publikováno v:
Hla
The experience of individuals with Coronavirus Disease 2019 (COVID-19) ranges from asymptomatic to life threatening multi-organ dysfunction. Specific HLA alleles may affect the predisposition to severe COVID-19 due to their role in presenting viral p
Autor:
Ana Olivo, Erika P. Orner, Karl G. Hock, Gavin Cloherty, Mei San Tang, Russell H. Taylor, John Prostko, Christopher W Farnsworth, Amy S. Fox, Mary Gardiner, Mary A. Rodgers
Publikováno v:
Diagnostic Microbiology and Infectious Disease
The clinical and public health utility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serologic testing requires a better understanding of the dynamics of the humoral response to infection. To track seroconversion of IgG and IgM anti
Publikováno v:
The Journal of Applied Laboratory Medicine
American Journal of Clinical Pathology
American Journal of Clinical Pathology
Background Guidelines from the CDC and the IDSA suggest the use of serologic testing to support the diagnosis of COVID-19 in individuals with high clinical suspicion that repeatedly test negative by diagnostic methods. Given that variability in speci