Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Karl Erik Hellstrom"'
Autor:
Huafeng Wei, Likun Zhao, Wei Li, Kexing Fan, Weizhu Qian, Sheng Hou, Hao Wang, Min Dai, Ingegerd Hellstrom, Karl Erik Hellstrom, Yajun Guo
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84927 (2013)
There is an urgent need for improved therapy for advanced ovarian carcinoma, which may be met by administering immune-modulatory monoclonal antibodies (mAbs) to generate a tumor-destructive immune response. Using the ID8 mouse ovarian cancer model, w
Externí odkaz:
https://doaj.org/article/fd69ef8574f749bb9ca0604b9da7b7b9
Purpose: Immunomodulatory mAbs can treat cancer, but cures are rare except for small tumors. Our objective was to explore whether the therapeutic window increases by combining mAbs with different modes of action and injecting them into tumors.Experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619f6241c81db2ce1eab08916b7f0b43
https://doi.org/10.1158/1078-0432.c.6524499.v1
https://doi.org/10.1158/1078-0432.c.6524499.v1
Expression of surface molecules in TIL of mice receiving mAb combinations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c3172a746f365cc4b8a948a0ec8d01
https://doi.org/10.1158/1078-0432.22460463.v1
https://doi.org/10.1158/1078-0432.22460463.v1
Expression of surface molecules in TLN and spleen of mice receiving the mAb treatments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6c1da687c0cc5608fcb1c1e1c46d18
https://doi.org/10.1158/1078-0432.22460469.v1
https://doi.org/10.1158/1078-0432.22460469.v1
Depleted of CD19 cells by the 4 mAb combination.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3a4a4cd2d9862887e23a3eb874b869
https://doi.org/10.1158/1078-0432.22460466.v1
https://doi.org/10.1158/1078-0432.22460466.v1
Figure legends for four supplementary figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a1e2f65f356c6cfdb6286c9d15e522
https://doi.org/10.1158/1078-0432.22460460
https://doi.org/10.1158/1078-0432.22460460
Publikováno v:
Journal of immunotherapy (Hagerstown, Md. : 1997). 44(9)
Immunologic mechanisms influence how a cancer patient responds to therapy. Monoclonal antibodies (mAbs) to the epidermal growth factor receptor are clinically approved, and a lung cancer vaccine inducing antibodies to epidermal growth factor (EGF) ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe9cf04f17a3293d1291f300d471ac9
https://pubmed.ncbi.nlm.nih.gov/34456294
https://pubmed.ncbi.nlm.nih.gov/34456294
Publikováno v:
Journal of Immunotherapy. 41:369-378
While immunomodulatory monoclonal antibodies (mAbs) have therapeutic efficacy against many tumors, few patients are cured. Attempting to improve their therapeutic efficacy we have applied the TC1 mouse lung carcinoma model and injected established su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c9b3e81472aa4f6520714276ec91f0
https://doi.org/10.1097/cji.0000000000000231
https://doi.org/10.1097/cji.0000000000000231
Publikováno v:
Progress in molecular biology and translational science. 164
Several decades ago we published some of the first papers showing that both murine and human cancers are recognized in vitro as immunologically foreign and that this is the case also in the presence of a growing tumor. The latter situation, sometimes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5eb16ca470177bb919e494928a90a8da
https://pubmed.ncbi.nlm.nih.gov/31383402
https://pubmed.ncbi.nlm.nih.gov/31383402
Several decades ago we published some of the first papers showing that both murine and human cancers are recognized in vitro as immunologically foreign and that this is the case also in the presence of a growing tumor. The latter situation, sometimes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee39937336539dbcda7cf82e83833eca
https://doi.org/10.1016/bs.pmbts.2018.11.002
https://doi.org/10.1016/bs.pmbts.2018.11.002