Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Karl Erik Hellström"'
Autor:
Ling Yi, Yanlin Zhao, Xiaojue Wang, Min Dai, Karl Erik Hellström, Ingegerd Hellström, Hongtao Zhang
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86337 (2014)
Monoclonal antibodies (mAbs) to CD137 (a.k.a. 4-1BB) have anti-tumor efficacy in several animal models and have entered clinical trials in patients with advanced cancer. Importantly, anti-CD137 mAbs can also ameliorate autoimmunity in preclinical mod
Externí odkaz:
https://doaj.org/article/15429aec82df4a3a972e97815f52a900
Publikováno v:
Methods in Pharmacology and Toxicology ISBN: 9781071601709
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77a545a2557ecb986f397070135c6fbe
https://doi.org/10.1007/978-1-0716-0171-6_1
https://doi.org/10.1007/978-1-0716-0171-6_1
Autor:
Ingegerd Hellström, Seby L. Edassery, Karl Erik Hellström, Nicole Urban, Yi Yu-Rice, Judith L. Luborsky, Yan Li, Youping Deng
Publikováno v:
Reproduction. 153:277-284
Infertility is a risk factor for ovarian cancer (OvCa). The goal was to determine if antibodies to selenium-binding protein 1 (SBP1), an autoantibody we identified in patients with premature ovarian failure (POF), occurs in both infertility and OvCa
Autor:
Yuen Yee Yip, Elizabeth M. Swisher, Kathy Agnew, Ingegerd Hellström, John B. Liao, Karl Erik Hellström
Publikováno v:
Gynecologic Oncology. 137:430-435
Objectives To measure HE4 levels in urine from normal donors, patients with LMP tumors and ovarian cancer patients and to correlate levels with clinical factors in ovarian cancer patients. Methods Archived samples from controls, patients with LMP tum
Publikováno v:
Human antibodies. 25(3-4)
Over the past several years remarkable therapeutic responses have been obtained with immunomodulatory monoclonal antibodies (mAbs), both in mice \cite{10,18,20,48,54,61} and human cancer patients \cite{1,3,14,28,30,39,80}. However, complete regressio
Publikováno v:
Clinical Cancer Research. 21:3581-3583
Vaccination with sipuleucel-T produced IgG antibodies to secondary prostatic carcinoma antigens and prolonged survival in some patients, and assaying for antibodies may provide prognostic information and identify new vaccine targets. Additional appro
Autor:
Janice Morihara, Mujun Yu, Joshua E. Stern, Nancy B. Kiviat, Ingegerd Hellström, Karl Erik Hellström, Qinghua Feng, Huafeng Wei
Publikováno v:
Gynecologic Oncology. 127:412-419
To investigate the role of immunological parameters in tumorigenesis of cervical cancer in women infected with high risk human papillomavirus (hr-HPV), and determine whether key findings with human material can be recapitulated in the mouse TC1 carci
Publikováno v:
Journal of immunotherapy (Hagerstown, Md. : 1997). 39(8)
Immunomodulatory monoclonal antibodies (mAbs) have efficacy in patients with advanced cancer and are the focus of intensive research. However, cures are infrequent and responses vary among tumor types and among subjects with the same tumor. An in vit
Autor:
Huafeng Wei, Kathy Agnew, Ingegerd Hellström, Karl Erik Hellström, Elizabeth M. Swisher, Yuen Yee Yip, Jee Hang Tse, Pu Liu
Publikováno v:
Journal of Immunotherapy. 35:267-275
Cells from many tumors produce transforming growth factor (TGF)-β which facilitates their escape from control by the immune system. We previously reported that nonimmunogenic cells from either of 2 transplantable mouse tumors became effective as the
Publikováno v:
Journal of Immunotherapy. 32:232-239
We have previously demonstrated that transplanted cells from the SW1 clone of the K1735 melanoma and the Ag104 sarcoma grow progressively in syngeneic C3H mice even after transfection to engage CD137, a procedure that increases the immunogenicity of