Zobrazeno 1 - 10
of 282
pro vyhledávání: '"Karl E, Kadler"'
Autor:
Maria Antonia Llopis-Grimalt, Marta Munar-Bestard, Guillem Ramis-Munar, David Smith, Tobias Starborg, Karl E. Kadler, Marta Monjo, Joana M. Ramis
Publikováno v:
ACS Omega, Vol 9, Iss 28, Pp 30534-30543 (2024)
Externí odkaz:
https://doaj.org/article/d39a26c0055444b1bad4a4cf2ba1c97f
Autor:
Sarah McNeilly, Cameron R. Thomson, Laura Gonzalez-Trueba, Yuan Yan Sin, Alessandra Granata, Graham Hamilton, Michelle Lee, Erin Boland, John D. McClure, Cristina Lumbreras-Perales, Alisha Aman, Apoorva A. Kumar, Marco Cantini, Caglar Gök, Delyth Graham, Yasuko Tomono, Christopher D. Anderson, Yinhui Lu, Colin Smith, Hugh S. Markus, Marc Abramowicz, Catheline Vilain, Rustam Al-Shahi Salman, Manuel Salmeron-Sanchez, Atticus H. Hainsworth, William Fuller, Karl E. Kadler, Neil J. Bulleid, Tom Van Agtmael
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105315- (2024)
Summary: Background: Genetic variants in COL4A1 and COL4A2 (encoding collagen IV alpha chain 1/2) occur in genetic and sporadic forms of cerebral small vessel disease (CSVD), a leading cause of stroke, dementia and intracerebral haemorrhage (ICH). Ho
Externí odkaz:
https://doaj.org/article/d38bd2e3219f479e9d1e302cbcbad3f9
Publikováno v:
Matrix Biology Plus, Vol 22, Iss , Pp 100147- (2024)
Externí odkaz:
https://doaj.org/article/c268752903b442fda7d7406cf8ade9c8
Autor:
Christopher K. Revell, Oliver E. Jensen, Tom Shearer, Yinhui Lu, David F. Holmes, Karl E. Kadler
Publikováno v:
Matrix Biology Plus, Vol 12, Iss , Pp 100079- (2021)
Collagen fibrils are essential for metazoan life. They are the largest, most abundant, and most versatile protein polymers in animals, where they occur in the extracellular matrix to form the structural basis of tissues and organs. Collagen fibrils w
Externí odkaz:
https://doaj.org/article/6841698ba4e5457fa8e7a39cd16b6954
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009840 (2021)
COVID-19 vaccines based on the Spike protein of SARS-CoV-2 have been developed that appear to be largely successful in stopping infection. However, therapeutics that can help manage the disease are still required until immunity has been achieved glob
Externí odkaz:
https://doaj.org/article/33c38e8b624545e7a21beda01b97b102
Autor:
Heba Shawer, Esther Aiyelaagbe, Christopher Clowes, Samantha C Lean, Yinhui Lu, Karl E Kadler, Alan Kerby, Mark R Dilworth, Kathryn E Hentges, Alexander E P Heazell
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233007 (2020)
BackgroundIn humans, stillbirth describes the death of a fetus before birth after 28 weeks gestation, and accounts for approximately 2.6 million deaths worldwide annually. In high-income countries, up to half of stillbirths have an unknown cause and
Externí odkaz:
https://doaj.org/article/bde0bfa951944a7fbce9950e6e922abc
Autor:
Christopher K. Revell, Jeremy A. Herrera, Craig Lawless, Yinhui Lu, Karl E. Kadler, Joan Chang, Oliver E. Jensen
Collagen is a key structural component of multicellular organisms and is arranged in a highly organised manner. In structural tissues such as tendons, collagen forms bundles of parallels fibres between cells, which appear within a 24 hour window betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fff6aa4bc872c223f948e8e5448229fb
https://doi.org/10.1101/2023.03.13.532430
https://doi.org/10.1101/2023.03.13.532430
Autor:
Ching‐Yan Chloé Yeung, René B. Svensson, Kateryna Yurchenko, Nikolaj M. Malmgaard‐Clausen, Ida Tryggedsson, Marius Lendal, Anja Jokipii‐Utzon, Jens L. Olesen, Yinhui Lu, Karl E. Kadler, Peter Schjerling, Michael Kjær
Publikováno v:
The Journal of Physiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6713aa0154df1dd3765780bae0bb60f8
https://doi.org/10.1113/jp284083
https://doi.org/10.1113/jp284083
Publikováno v:
Cells, Vol 10, Iss 3, p 662 (2021)
With the increased awareness about the importance of the composition, organization, and stiffness of the extracellular matrix (ECM) for tissue homeostasis, there is a renewed need to understand the details of how cells recognize, assemble and remodel
Externí odkaz:
https://doaj.org/article/da1f46fbf49d4e1f972bd16a74db327c
Autor:
Frances E. Jones, Matthew A. Bailey, Lydia S. Murray, Yinhui Lu, Sarah McNeilly, Ursula Schlötzer-Schrehardt, Rachel Lennon, Yoshikazu Sado, David G. Brownstein, John J. Mullins, Karl E. Kadler, Tom Van Agtmael
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 2, Pp 165-176 (2016)
Collagen IV is a major component of basement membranes, and mutations in COL4A1, which encodes collagen IV alpha chain 1, cause a multisystemic disease encompassing cerebrovascular, eye and kidney defects. However, COL4A1 renal disease remains poorly
Externí odkaz:
https://doaj.org/article/ca3dc48772f04bf2b39a587f4c1bb2ff