Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Karl E, Duderstadt"'
Autor:
Nadia M Huisjes, Thomas M Retzer, Matthias J Scherr, Rohit Agarwal, Lional Rajappa, Barbara Safaric, Anita Minnen, Karl E Duderstadt
Publikováno v:
eLife, Vol 11 (2022)
The rapid development of new imaging approaches is generating larger and more complex datasets, revealing the time evolution of individual cells and biomolecules. Single-molecule techniques, in particular, provide access to rare intermediates in comp
Externí odkaz:
https://doaj.org/article/603a854eaa0345e0b0f64723b26a749d
Publikováno v:
Cell Reports, Vol 38, Iss 12, Pp 110531- (2022)
Summary: Fundamental to our understanding of chromosome duplication is the idea that replication origins function both as sites where MCM helicases are loaded during the G1 phase and where synthesis begins in S phase. However, the temporal delay betw
Externí odkaz:
https://doaj.org/article/4c5d813da3cf49959b2ac46f6ad4941a
Autor:
Rohit Agarwal, Karl E. Duderstadt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Single molecule force measurements have shed light on dynamic biological events, but rare events escape notice owing to low throughput of the methods. Here, the authors combine an array of magnetic tweezers with lateral flow to increase throughput 10
Externí odkaz:
https://doaj.org/article/d57278de37904fdbafba88ac63c97298
Autor:
Bart J. H. Dequeker, Matthias J. Scherr, Hugo B. Brandão, Johanna Gassler, Sean Powell, Imre Gaspar, Ilya M. Flyamer, Aleksandar Lalic, Wen Tang, Roman Stocsits, Iain F. Davidson, Jan-Michael Peters, Karl E. Duderstadt, Leonid A. Mirny, Kikuë Tachibana
Publikováno v:
Nature
Eukaryotic genomes are compacted into loops and topologically associating domains (TADs)1–3, which contribute to transcription, recombination and genomic stability4,5. Cohesin extrudes DNA into loops that are thought to lengthen until CTCF boundari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc53de26f6a5b4349e849f02bf18469
https://doi.org/10.1038/s41586-022-04730-0
https://doi.org/10.1038/s41586-022-04730-0
Autor:
Barbara Safaric, Erika Chacin, Matthias J Scherr, Lional Rajappa, Christian Gebhardt, Christoph F Kurat, Thorben Cordes, Karl E Duderstadt
Publikováno v:
Nucleic Acids Research
Chromosome replication depends on efficient removal of nucleosomes by accessory factors to ensure rapid access to genomic information. Here, we show this process requires recruitment of the nucleosome reorganization activity of the histone chaperone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d533d27c64a9ba91023903331dd2a6e5
https://doi.org/10.1093/nar/gkac005
https://doi.org/10.1093/nar/gkac005
Autor:
Jacob S Lewis, Lisanne M Spenkelink, Slobodan Jergic, Elizabeth A Wood, Enrico Monachino, Nicholas P Horan, Karl E Duderstadt, Michael M Cox, Andrew Robinson, Nicholas E Dixon, Antoine M van Oijen
Publikováno v:
eLife, Vol 6 (2017)
The Escherichia coli DNA replication machinery has been used as a road map to uncover design rules that enable DNA duplication with high efficiency and fidelity. Although the enzymatic activities of the replicative DNA Pol III are well understood, it
Externí odkaz:
https://doaj.org/article/146175f49fcc48049bc88b2ce1fc710c
Autor:
Nadia M Huisjes, Thomas M Retzer, Matthias J Scherr, Rohit Agarwal, Lional Rajappa, Barbara Safaric, Anita Minnen, Karl E Duderstadt
Publikováno v:
eLife. 11
The rapid development of new imaging approaches is generating larger and more complex datasets, revealing the time evolution of individual cells and biomolecules. Single-molecule techniques, in particular, provide access to rare intermediates in comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed77bc9f83caa2559709815dc2a422e8
https://pubmed.ncbi.nlm.nih.gov/36098381
https://pubmed.ncbi.nlm.nih.gov/36098381
Autor:
Annemarie Lüdecke, Marta Urbanska, Wilhelm J. Walter, Stefan Diez, Karl E. Duderstadt, Antoine M. van Oijen
Publikováno v:
Small, 17(18):2007388. WILEY-V C H VERLAG GMBH
Small
Small
Cytoskeletal motors transform chemical energy into mechanical work to drive essential cellular functions. Optical trapping experiments have provided crucial insights into the operation of these molecular machines under load. However, the throughput o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf2d7f0f96ae50d339d04c84c3a57bd
https://research.rug.nl/en/publications/95a1aac5-2bc4-46ac-8f55-c7ddc8011d13
https://research.rug.nl/en/publications/95a1aac5-2bc4-46ac-8f55-c7ddc8011d13
Publikováno v:
SSRN Electronic Journal.
Fundamental to our understanding of chromosome duplication is the idea that replication origins function both as sites where MCM helicases are loaded during the G1 phase and where synthesis begins in S phase. However, the temporal delay between these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be91f89e9aec382bcd9664df02093d9c
https://doi.org/10.2139/ssrn.3775178
https://doi.org/10.2139/ssrn.3775178