Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Karl Deres"'
Publikováno v:
Journal of Virology. 78:13812-13818
The carboxy-terminal sequence of the hepatitis B virus (HBV) core protein constitutes a nucleic acid binding domain that is rich in arginine residues and contains three serine phosphorylation sites. While dispensable for capsid assembly, this domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ec6e10c23b4f42fcf055ee505a0728
https://doi.org/10.1128/jvi.78.24.13812-13818.2004
https://doi.org/10.1128/jvi.78.24.13812-13818.2004
Autor:
Stanley G. Nathenson, Ton N. Schumacher, Hidde L. Ploegh, Grada M. van Bleek, Mónica Imarai, Marie Therese Heemels, Ka Wan Li, Karl Deres, L.N. Vernie
Publikováno v:
European Journal of Immunology. 22:1405-1412
Major histocompatibility complex (MHC) class I molecules combine with short peptides of defined length and sequence. Here we describe an approach that may be used in the analysis of peptide preference of different allelic MHC class I molecules, and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47bde739030ac829cc8b7113db7b9b76
https://doi.org/10.1002/eji.1830220612
https://doi.org/10.1002/eji.1830220612
Publikováno v:
Biochemical pharmacology. 66(12)
Recently, heteroarylpyrimidines (HAP) have been identified as potent inhibitors of capsid maturation. Here we discuss the HAP mode of action comparing the aggregation phenotype of wild-type and mutant core proteins with the respective phenotype impos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2865d1699cbdaf0eb838b1500f5bd959
https://pubmed.ncbi.nlm.nih.gov/14637185
https://pubmed.ncbi.nlm.nih.gov/14637185
Publikováno v:
Viral Infections and Treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecd892e499af1b5a2dcd7f0b140cd19a
https://doi.org/10.1201/b14823
https://doi.org/10.1201/b14823
Autor:
Hans Jörg Hacker, Karl-Heinz Schlemmer, Thomas Krämer, Ralf N. A. Masantschek, Ulrich Niewöhner, Jurgen D I Stoltefuss, Ruebsamen-Waigmann Helga, Arnold Paessens, Dieter Haebich, Anja Reimann, Erwin Graef, Diana Koletzki, Rainer Gros, Claus H. Schröder, Bernhard Beckermann, Olaf Weber, Siegfried Goldmann, Ulrich Pleiss, Karl Deres, Rainer Jaeger
Publikováno v:
Science (New York, N.Y.). 299(5608)
Chronic hepatitis B virus (HBV) infection is a major cause of liver disease. Only interferon-α and the nucleosidic inhibitors of the viral polymerase, 3TC and adefovir, are approved for therapy. However, these therapies are limited by the side effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa3ba589894ef480de5911e9445ad3a
https://pubmed.ncbi.nlm.nih.gov/14999705
https://pubmed.ncbi.nlm.nih.gov/14999705
Autor:
Dieter Haebich, Olaf Weber, E. Hartmann, Helga Prof Ruebsamen-Waigmann, Arnold Dr. Paessens, U. Niewoehner, Graef Erwin, Jürgen Dr. Stoltefuss, Ina Hagelschuer, Karl Deres, S. Goldmann, K.-H. Schlemmer, Stefan Dr Wohlfeil
Publikováno v:
Antiviral research. 54(2)
BAY 41-4109 is a member of a class of heteroaryl-pyrimidines that was recently identified as potent inhibitors of human hepatitis B virus (HBV) replication. We have investigated the antiviral activity of BAY 41-4109 (methyl (R)-4-(2-chloro-4-fluoroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a46b1521319b63da7b5cc35e4212e3
https://pubmed.ncbi.nlm.nih.gov/12062392
https://pubmed.ncbi.nlm.nih.gov/12062392
Autor:
Jörg W. Metzger, Hansjörg Schild, Karl Deres, Günther Jung, Kirsten Falk, Maria Norda, Hans-Georg Rammensee, Olaf Rötzschke
Publikováno v:
Nature. 348:252-254
Virus-infected cells can be eliminated by cytotoxic T lymphocytes (CTL), which recognize virus-derived peptides bound to major histocompatibility complex (MHC) class I molecules on the cell surface. Until now, this notion has relied on overwhelming b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec94f160d69a792cf0de06e45e1e5c16
https://doi.org/10.1038/348252a0
https://doi.org/10.1038/348252a0
Publikováno v:
European journal of immunology. 28(3)
Ceramide generated by lysosomal acid sphingomyelinase (aSMase) has been proposed to contribute to CD28 co-stimulatory signaling pathways. We used an aSMase-deficient mouse line ( asmase − / − ) to elucidate the role of the aSMase in splenocytes s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd45f2a1c27767b7d983b0cfd700744a
https://pubmed.ncbi.nlm.nih.gov/9541582
https://pubmed.ncbi.nlm.nih.gov/9541582
Autor:
Manuel Loleit, Marianne Eckert, Karl-Heinz Wiesmüller, Karl Deres, Wolfgang G. Bessler, Günther Jung
Publikováno v:
Biological chemistry Hoppe-Seyler. 375(6)
The lipoprotein (LP) from Escherichia coli and other Enterobacteriaceae as well as lipoprotein derived lipopeptides constitute potent B lymphocyte mitogens. Several synthetic peptide segments of the lipoprotein were tested for mitogenic activity towa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe650ca66458baaec267582a1926fd5
https://pubmed.ncbi.nlm.nih.gov/7980873
https://pubmed.ncbi.nlm.nih.gov/7980873
Publikováno v:
Cellular immunology. 151(1)
MHC class I molecules present octa- or nonapeptides derived from cellular proteins. Such peptides adhere to strict rules, which are individual to each MHC allele. Synthetic peptides conforming to these rules or peptides being at variance at critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c965aef02203f213f194be6370d96a
https://pubmed.ncbi.nlm.nih.gov/8402926
https://pubmed.ncbi.nlm.nih.gov/8402926