Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Karl Dean"'
Autor:
Alejandra B. Goya, Danial Baqer, Ryan P. Alexander, Patrycja Stubbs, Karl Dean, Adam M. Lewis, Lewis Coates, Benjamin H. Maskrey, Andrew D. Turner
Publikováno v:
Marine Drugs, Vol 20, Iss 10, p 634 (2022)
Harmful algal blooms are an increasing worldwide threat to the seafood industry and human health as a consequence of the natural production of biotoxins that can accumulate in shellfish. In the Argentine Sea, this has been identified as an issue for
Externí odkaz:
https://doaj.org/article/94c326fa193145b2845b5f261240bdcc
Autor:
Andrew D. Turner, Monika Dhanji-Rapkova, Karl Dean, Steven Milligan, Mike Hamilton, Julie Thomas, Chris Poole, Jo Haycock, Jo Spelman-Marriott, Alice Watson, Katherine Hughes, Bridget Marr, Alan Dixon, Lewis Coates
Publikováno v:
Toxins, Vol 10, Iss 3, p 94 (2018)
At the start of 2018, multiple incidents of dog illnesses were reported following consumption of marine species washed up onto the beaches of eastern England after winter storms. Over a two-week period, nine confirmed illnesses including two canine d
Externí odkaz:
https://doaj.org/article/4505ee71a3de40d9b5e24930ea4ff6af
Autor:
JoAnne Dzink-Fox, Jason T. Brewer, Esther K. Schmitt, Karl Dean, Matthew J. LaMarche, Stacey Tiamfook, Gabe Gamber, Zachary Robinson, Jennifer A. Leeds, Michael A. Patane, Deborah Palestrant, Colin Osborne, Franco Lombardo, Akash K. Jain, David McKenney, Jian Ding, Lewis Whitehead, Philipp Krastel, Elin M. Rann, Travis Stams, Donghui Yu, Ryan Kerrigan, Georg Neckermann, Kwangho Lee
Publikováno v:
Journal of medicinal chemistry. 59(14)
Synthetic studies of the antimicrobial secondary metabolite thiomuracin A (1) provided access to analogues in the Northern region (C2–C10). Selective hydrolysis of the C10 amide of lead compound 2 and subsequent derivatization led to novel carbon-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e6e2e5b9088dc74bc09de581c51bc2
https://pubmed.ncbi.nlm.nih.gov/27355833
https://pubmed.ncbi.nlm.nih.gov/27355833
Autor:
Dhananjay Kumar Srivastava, Karl Dean, Li Cao, Jens Krueger Venus, Hongming Xu, Adam Weall, Po-Wen Tu, Daliang Jing
Publikováno v:
SAE Technical Paper Series.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb8c19098e1192c4a3a3a6bd08eafa05
https://doi.org/10.4271/2015-01-1906
https://doi.org/10.4271/2015-01-1906
Autor:
Karl Dean, Apurva Chaudhary, Dana Wambser, Oljan Repic, Martin Mueller, Hui Liu, Joginder S. Bajwa, Helmut Boehnke, Kathryn Rene Bracken, Paul G. Lee, Thomas J. Blacklock, Vivelo James Anthony, Joseph Carosi, Kapa Prasad, Michael J. Girgis, Joel Slade, Guang-Pei Chen, David Thomas Parker
Publikováno v:
Organic Process Research & Development. 10:78-93
A practical synthesis of the peptide deformylase inhibitor LBM415, (2S)-N-(5-fluoro-1-oxido-2-pyridinyl)-1-[(2R)-2-[(formylhydroxyamino)methyl]-1-oxohexyl]-2-pyrrolidinecarboxamide, magnesium salt 11, is described. The key chiral intermediate, (2S)-N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::235d589a0750f7d99f4094c42ae298b3
https://doi.org/10.1021/op050165y
https://doi.org/10.1021/op050165y
Autor:
Stacy W. Remiszewski, Lidia C. Sambucetti, Kenneth W. Bair, John Bontempo, David Cesarz, Nagarajan Chandramouli, Ru Chen, Min Cheung, Susan Cornell-Kennon, Karl Dean, George Diamantidis, Dennis France, Michael A. Green, Kobporn Lulu Howell, Rina Kashi, Paul Kwon, Peter Lassota, Mary S. Martin, Yin Mou, Lawrence B. Perez, Sushil Sharma, Troy Smith, Eric Sorensen, Francis Taplin, Nancy Trogani, Richard Versace, Heather Walker, Susan Weltchek-Engler, Alexander Wood, Arthur Wu, Peter Atadja
Publikováno v:
Journal of Medicinal Chemistry. 46:4609-4624
A series of N-hydroxy-3-phenyl-2-propenamides were prepared as novel inhibitors of human histone deacetylase (HDAC). These compounds were potent enzyme inhibitors, having IC50s < 400 nM in a partially purified enzyme assay. However, potency in cell g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e0206bc14fdb324b1acbdd17eeea9cc
https://doi.org/10.1021/jm030235w
https://doi.org/10.1021/jm030235w
Autor:
Brian Granda, Gejing Deng, Sompong Wattanasin, Rui Zhang, Neil S. Ryder, Karl Dean, Jianshi Tao, Lac Lee, Xiaoling Xie, Tommasi Ruben A, Eugene Liu, Stefan Peukert
Publikováno v:
Biochemistry
Undecaprenyl pyrophosphate synthase (UPPS) catalyzes the consecutive condensation of eight molecules of isopentenyl pyrophosphate (IPP) with farnesyl pyrophosphate (FPP) to generate the C(55) undecaprenyl pyrophosphate (UPP). It has been demonstrated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b451a5a936d09b93dcfbc2397473a4a2
https://pubmed.ncbi.nlm.nih.gov/20476728
https://pubmed.ncbi.nlm.nih.gov/20476728
Autor:
Neil S. Ryder, Kathryn Rene Bracken, JoAnn Dzink-Fox, Rakesh K. Jain, Zhengyu Yuan, Charles R. Dean, Karl Dean, Beat Weidmann, Shubha Narayan, Denis M. Daigle, Xiaoling Puyang
Haemophilus influenzae isolates vary widely in their susceptibilities to the peptide deformylase inhibitor LBM415 (MIC range, 0.06 to 32 μg/ml); however, on average, they are less susceptible than gram-positive organisms, such as Staphylococcus aure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9745719fbeda1956e12def26c69d73c6
https://europepmc.org/articles/PMC1196275/
https://europepmc.org/articles/PMC1196275/
Autor:
Tanner, Karl Dean.
Publikováno v:
Electronic Theses and Dissertations
Within the field of urban planning there is a growing recognition that the discipline must incorporate within its existing framework an environmental component that is sensitive to environmental concerns and which takes a proactive role. It is no lon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2870::5bbfa9cad6973da1d9a88cee3ac16996
https://scholar.uwindsor.ca/context/etd/article/2030/viewcontent/mm01491_uwindsor.pdf
https://scholar.uwindsor.ca/context/etd/article/2030/viewcontent/mm01491_uwindsor.pdf
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