Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Karl D Murray"'
Autor:
Jie-Xian Dong, Yongam Lee, Michael Kirmiz, Stephanie Palacio, Camelia Dumitras, Claudia M Moreno, Richard Sando, L Fernando Santana, Thomas C Südhof, Belvin Gong, Karl D Murray, James S Trimmer
Publikováno v:
eLife, Vol 8 (2019)
Nanobodies (nAbs) are small, minimal antibodies that have distinct attributes that make them uniquely suited for certain biomedical research, diagnostic and therapeutic applications. Prominent uses include as intracellular antibodies or intrabodies t
Externí odkaz:
https://doaj.org/article/13ea854aadef4d35bafff7c930066b21
Autor:
Nicolas P Andrews, Justin X Boeckman, Colleen F Manning, Joe T Nguyen, Hannah Bechtold, Camelia Dumitras, Belvin Gong, Kimberly Nguyen, Deborah van der List, Karl D Murray, JoAnne Engebrecht, James S Trimmer
Publikováno v:
eLife, Vol 8 (2019)
Generating recombinant monoclonal antibodies (R-mAbs) from mAb-producing hybridomas offers numerous advantages that increase the effectiveness, reproducibility, and transparent reporting of research. We report here the generation of a novel resource
Externí odkaz:
https://doaj.org/article/59976df2d6b046219b7ee9969a2fedc2
Autor:
Xiaomeng Han, Xiaotang Lu, Peter H. Li, Shuohong Wang, Richard Schalek, Yaron Meirovitch, Zudi Lin, Jason Adhinarta, Karl D. Murray, Leah M. MacNiven, Daniel R. Berger, Yuelong Wu, Tao Fang, Elif Sevde Meral, Shadnan Asraf, Hidde Ploegh, Hanspeter Pfister, Donglai Wei, Viren Jain, James S. Trimmer, Jeff W. Lichtman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Mapping neuronal networks is a central focus in neuroscience. While volume electron microscopy (vEM) can reveal the fine structure of neuronal networks (connectomics), it does not provide molecular information to identify cell types or funct
Externí odkaz:
https://doaj.org/article/af6d34c529a5478a859e10bc1f1a99bb
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19396 (2011)
Cancer cells often employ developmental cues for advantageous growth and metastasis. Here, we report that an axon guidance molecule, Sema3E, is highly expressed in human high-grade ovarian endometrioid carcinoma, but not low-grade or other ovarian ep
Externí odkaz:
https://doaj.org/article/86bbe69ad68a440a973aaee84c305a61
Autor:
Keith G. Mitchell, Belvin Gong, Samuel S. Hunter, Diana Burkart-Waco, Clara E. Gavira-O’Neill, Kayla M. Templeton, Madeline E. Goethel, Malgorzata Bzymek, Leah M. MacNiven, Karl D. Murray, Matthew L. Settles, Lutz Froenicke, James S. Trimmer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract The Neuroscience Monoclonal Antibody Sequencing Initiative (NeuroMabSeq) is a concerted effort to determine and make publicly available hybridoma-derived sequences of monoclonal antibodies (mAbs) valuable to neuroscience research. Over 30 ye
Externí odkaz:
https://doaj.org/article/fa6b1a4ba7354527aeab55348adfee67
Autor:
Maria Casas, Karl D. Murray, Keiko Hino, Nicholas C. Vierra, Sergi Simó, James S. Trimmer, Rose E. Dixon, Eamonn J. Dickson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Lysosomes communicate through cholesterol transfer at endoplasmic reticulum (ER) contact sites. At these sites, the Niemann Pick C1 cholesterol transporter (NPC1) facilitates the removal of cholesterol from lysosomes, which is then transferr
Externí odkaz:
https://doaj.org/article/8e457916b01b415d80b45482e83ca4c6
Autor:
Joseph C. Boktor, Mark D. Adame, Destanie R. Rose, Cynthia M. Schumann, Karl D. Murray, Melissa D. Bauman, Milo Careaga, Sarkis K. Mazmanian, Paul Ashwood, Brittany D. Needham
Publikováno v:
Molecular psychiatry, vol 27, iss 12
Mol Psychiatry
Mol Psychiatry
Epidemiological evidence implicates severe maternal infections as risk factors for neurodevelopmental disorders, such as ASD and schizophrenia. Accordingly, animal models mimicking infection during pregnancy, including the maternal immune activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871944e03223b1a96446dedd15fceb21
https://escholarship.org/uc/item/51r9k74s
https://escholarship.org/uc/item/51r9k74s
Autor:
Donna L. Smith, Ruben Portier, Ben Woodman, Emma Hockly, Amarbirpal Mahal, William E. Klunk, Xiao-Jiang Li, Erich Wanker, Karl D. Murray, Gillian P. Bates
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 6, Pp 1017-1026 (2001)
Huntington's disease (HD) is a late onset neurodegenerative disorder caused by a CAG/polyglutamine (polyQ) repeat expansion. PolyQ aggregates can be detected in the nuclei and processes of neurons in HD patients and mouse models prior to the onset of
Externí odkaz:
https://doaj.org/article/fa08d20b29484b8d8f8a3bbfc905b226
Publikováno v:
eNeuro
eNeuro, vol 7, iss 3
eNeuro, vol 7, iss 3
Mouse hippocampus retains the capacity for neurogenesis throughout lifetime, but such plasticity decreases with age. Adult hippocampal neurogenesis (AHN) involves the birth, maturation, and synaptic integration of newborn granule cells (GCs) into pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2dd1561fbd6d6b78956f1257fd8089
https://pubmed.ncbi.nlm.nih.gov/32332082
https://pubmed.ncbi.nlm.nih.gov/32332082
Autor:
Belvin Gong, Yongam Lee, Thomas C. Südhof, Karl D Murray, Michael Kirmiz, Camelia Dumitras, Richard Sando, Jie Xian Dong, L. Fernando Santana, James S. Trimmer, Stephanie Palacio, Claudia M. Moreno
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Nanobodies (nAbs) are small, minimal antibodies that have distinct attributes that make them uniquely suited for certain biomedical research, diagnostic and therapeutic applications. Prominent uses include as intracellular antibodies or intrabodies t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fde6cf825ad7a30713dcbe449b36e5
http://europepmc.org/articles/PMC6785268
http://europepmc.org/articles/PMC6785268