Zobrazeno 1 - 10
of 407
pro vyhledávání: '"Karl A Nath"'
Autor:
Kathryn T. delValle, Michael J. Krowka, Carrie A. Schinstock, Karl A. Nath, Charles D. Burger, Yogesh N. Reddy, Robert P. Frantz, Y. S. Prakash, Hilary M. DuBrock
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Pulmonary hypertension (PH) associated with chronic kidney disease (CKD) (PH‐CKD) affects approximately 20%–40% of CKD patients and is associated with increased morbidity and mortality. PH and CKD are both pathophysiologically associated
Externí odkaz:
https://doaj.org/article/13ff566423274794ba828f545f932864
Autor:
George R. Marcotte, Matthew J. Miller, Hawley E. Kunz, Zachary C. Ryan, Matthew D. Strub, Patrick M. Vanderboom, Carrie J. Heppelmann, Sarah Chau, Zachary D. Von Ruff, Sean P. Kilroe, Andrew T. McKeen, Jason M. Dierdorff, Jennifer I. Stern, Karl A. Nath, Chad E. Grueter, Vitor A. Lira, Andrew R. Judge, Blake B. Rasmussen, K. Sreekumaran Nair, Ian R. Lanza, Scott M. Ebert, Christopher M. Adams
Publikováno v:
JCI Insight, Vol 8, Iss 22 (2023)
Aging and many illnesses and injuries impair skeletal muscle mass and function, but the molecular mechanisms are not well understood. To better understand the mechanisms, we generated and studied transgenic mice with skeletal muscle–specific expres
Externí odkaz:
https://doaj.org/article/af1307b64c1b4419953e38f85ed47944
Autor:
Silvana B. De Lorenzo, Alyssa M. Vrieze, Ruth A. Johnson, Karen R. Lien, Karl A. Nath, Vesna D. Garovic, Khashayarsha Khazaie, Joseph P. Grande
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Progression of virtually all forms of chronic kidney disease (CKD) is associated with activation of pro-inflammatory and pro-fibrotic signaling pathways. Despite extensive research, progress in identifying therapeutic targets to arrest or slow progre
Externí odkaz:
https://doaj.org/article/d023f009a676492d84a51e7a6764bade
Autor:
Sonja Suvakov, Ranine Ghamrawi, Hajrunisa Cubro, Haitao Tu, Wendy M. White, Yvonne S. Butler Tobah, Natasa M. Milic, Joseph P. Grande, Julie M. Cunningham, Fouad T. Chebib, Larissa G.P. Langhi Prata, Yi Zhu, Tamara Tchkonia, James L. Kirkland, Karl A. Nath, Aleksandar Milosavljevic, Vesna D. Garovic
Publikováno v:
EBioMedicine, Vol 70, Iss , Pp 103536- (2021)
Background: Preeclampsia is a pregnancy-specific hypertensive disorder characterized by proteinuria and/or multisystem involvement. Disease-specific therapy has yet to be developed due to the lack of understanding of underlying mechanism(s). We postu
Externí odkaz:
https://doaj.org/article/2d6a2d2b00854797803a0525e383c515
Autor:
Karl A. Nath, Vesna D. Garovic
Publikováno v:
Mayo Clinic Proceedings. 98:509-512
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::206250c1a34166c9b4e6f30e855509a3
https://doi.org/10.1016/j.mayocp.2023.02.006
https://doi.org/10.1016/j.mayocp.2023.02.006
Autor:
Sanjeev Sethi, Benjamin Madden, Marta Casal Moura, Raman Deep Singh, Samih H. Nasr, Jean Hou, Alok Sharma, Karl A. Nath, Ulrich Specks, Fernando C. Fervenza, Mark Haas
Publikováno v:
Journal of the American Society of Nephrology. 34:374-384
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39522049ae8f2af2669fbcbb7eaf50af
https://doi.org/10.1681/asn.0000000000000061
https://doi.org/10.1681/asn.0000000000000061
Autor:
John D. Belcher, Ping Zhang, Julia Nguyen, Zachary M. Kiser, Karl A. Nath, Jianjun Hu, John O. Trent, Gregory M. Vercellotti
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Myeloid differentiation factor-2 (MD-2) binds lipopolysaccharide (LPS) and initiates toll-like receptor-4 (TLR4) pro-inflammatory signaling. Heme also activates TLR4 signaling, but it is unknown if heme interacts with MD-2. Therefore, we examined MD-
Externí odkaz:
https://doaj.org/article/99eb18fc3b6b43cfa494c8c1667c1c26
Autor:
Karl A. Nath
Publikováno v:
Mayo Clinic Proceedings. 98:641-643
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ee965188844d8d000920e7e71a78a1f
https://doi.org/10.1016/j.mayocp.2023.03.018
https://doi.org/10.1016/j.mayocp.2023.03.018
Autor:
Karl A. Nath
Publikováno v:
Mayo Clinic Proceedings. 98:497-499
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dd83f796bba9ecf4fe6fdf3e856f0f8
https://doi.org/10.1016/j.mayocp.2023.02.021
https://doi.org/10.1016/j.mayocp.2023.02.021
Publikováno v:
Kidney360
Heme proteins, the stuff of life, represent an ingenious biologic strategy that capitalizes on the biochemical versatility of heme, and yet is one that avoids the inherent risks to cellular vitality posed by unfettered and promiscuously reactive heme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386598dcb9b2dbbe80b7a6099a5a60e0
https://doi.org/10.34067/kid.0005442022
https://doi.org/10.34067/kid.0005442022