Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Karl Winkler"'
Autor:
Christine Contini, Martin Jansen, Brigitte König, Filiz Markfeld-Erol, Mirjam Kunze, Stefan Zschiedrich, Ulrich Massing, Irmgard Merfort, Heinrich Prömpeler, Ulrich Pecks, Karl Winkler, Gerhard Pütz
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-11 (2018)
Abstract Background Preeclampsia is a life-threatening disease in pregnancy, and its complex pathomechanisms are poorly understood. In preeclampsia, lipid metabolism is substantially altered. In late onset preeclampsia, remnant removal disease like l
Externí odkaz:
https://doaj.org/article/2bbdc387dc2044ffb475a446b10fc508
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 5, Pp 882-893 (2016)
Lipoproteins play a key role in the development of CVD, but the dynamics of lipoprotein metabolism are difficult to address experimentally. This article describes a novel two-step combined in vitro and in silico approach that enables the estimation o
Externí odkaz:
https://doaj.org/article/75b2303e196b4e0e9e86320123e60877
Publikováno v:
Biochemical and biophysical research communications. 643
We investigated the effects of different lipids on the activity of the angiotensin II type 1 receptor (AT1R). As calcium plays a key role in the signaling of the AT1R, we used the calcium-sensitive fluorescence indicators fura-2 to detect intracellul
Publikováno v:
Water, Vol 10, Iss 10, p 1385 (2018)
Arsenic in drinking water resources and, especially, in groundwater, represents a severe health problem for millions of people in affected regions. This paper investigates a removal technology combining non-thermal plasma at a reaction time of 30 min
Externí odkaz:
https://doaj.org/article/81b4171a055746c6902e8c68ea9f44f6
Publikováno v:
Atherosclerosis Supplements. 40:61-67
Based on an early suggestion by Winkler et al. 2003 and a subsequent successful study by Wang et al. 2006 using lipid apheresis (LA) in 9 patients with preeclampsia to prolong pregnancies, the use of apheresis as therapeutic option in severe early on
Autor:
Christian Schäfer, Alexandr Parlesak, Joachim Eckoldt, Christiane Bode, Johann Christian Bode, Winfried März, Karl Winkler
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 7, Pp 1550-1558 (2007)
The reduction of cardiovascular mortality associated with moderate alcohol consumption is chiefly thought to be mediated by an increase of high density lipoprotein cholesterol (HDL-CH). This study highlights additional qualitative changes of HDL that
Externí odkaz:
https://doaj.org/article/5f5736eb01d64f2eb50986ea22349380
Publikováno v:
Journal of Laboratory Medicine, Vol 44, Iss 3, Pp 113-115 (2020)
Objectives Clinical laboratory analyses are essential part of critical care. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/coronavirus disease 2019 (COVID-19)-confirmed cases were doubling in Germany every 3 days during March 2020. Hea
Publikováno v:
Journal of Environmental Chemical Engineering. 6:7377-7385
Treatment with non-thermal plasma (NTP) is a promisingmethod to remove potentially harmful pharmaceuticals from wastewater treatment plant (WWTP) effluent. An application-oriented pilot-scale study was conducted to investigate the performance of an i
Autor:
Romeo Ngoune, Dominik von Elverfeldt, Michael M. Hoffmann, Karl Winkler, Gerhard Pütz, Christine Contini
Publikováno v:
Current Drug Delivery
Background Nanoscale drug delivery systems accumulate in solid tumors preferentially by the enhanced permeation and retention effect (EPR-effect). Nevertheless, only a miniscule fraction of a given dosage reaches the tumor, while >90% of the given dr
Autor:
Karl Winkler, Hubert Scharnagl, Ursula Tisljar, Heinz Hoschützky, Isolde Friedrich, Michael M. Hoffmann, Manfred Hüttinger, Heinrich Wieland, Winfried März
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 3, Pp 447-455 (1999)
The genetic polymorphism of apolipoprotein E (apoE) is associated with the age of onset and relative risk of Alzheimer's disease (AD). In contrast to apoE3, the wild type allele, apoE4 confers an increased risk of late-onset AD. We demonstrate that t
Externí odkaz:
https://doaj.org/article/82e1ed3c7b8c43a2800b1fa143b71a49